A Cross-Sectional Study of Primary Biliary Cirrhosis in Japan : Utilization of Clinical Data When Patients Applied to Receive Public Financial Aid
スポンサーリンク
概要
- 論文の詳細を見る
BACKGROUND: There have not been many reports regarding primary biliary cirrhosis (PBC) in Asia. We conducted a cross-sectional study of PBC in Japan.METHODS: In fiscal year 1999, 9,761 patients with symptomatic PBC were registered to receive public financial aid from the Ministry of Health, Labour and Welfare of Japan. For our cross-sectional study we chose 5,805 patients whose clinical data had been written between 1999 and 2000, and statistically analyzed the data, including sex, age, major symptoms, and laboratory data.RESULTS: Our study estimated that the male-to-female ratio was 1:8.0. The median ages of male and female patients were 59 and 60 years, respectively. The major symptoms and physical findings were as follows: pruritus 53.3%, jaundice 11.3%, xanthomas 5.8%, splenomegaly 38.1%, and esophageal varices 19.1%. Antimitochondrial antibody (AMA) was positive in 86.6%, but its positive rate was lower among Japanese patients than among those in western countries. IgM levels were higher among AMApositive patients than among AMA-negative patients. Regarding Sjogrens syndrome, rheumatoid arthritis, chronic thyroiditis, and scleroderma, patients had lower frequencies of complicated autoimmune diseases than those in western countries.CONCLUSIONS: The male-to-female ratio, frequencies by age group, symptoms and physical findings among patients with PBC were consistent with previous reports in Japan and from other countries. However, positivity of AMA and the frequency of complicated autoimmune diseases were lower among patients in Japan than among those in western countries.J Epidemiol2005; 15: 24-28.
- 日本疫学会の論文
- 2005-01-01
著者
-
MORI Mitsuru
Department of Public Health, Sapporo Medical University School of Medicine
-
SAKAUCHI Fumio
Department of Public Health, Sapporo Medical University School of Medicine
-
TODA Gotaro
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University Schoo
-
ZENIYA Mikio
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University Schoo
-
Toda Gotaro
東京慈恵会医科大学 消化器肝臓内科
-
Toda G
Division Of Gastroenterology And Hepatology Department Of Internal Medicine Jikei University School
-
Sakauchi Fumio
Department Of Public Health Sapporo Medical University School Of Medicine
-
Sakauchi Fumio
札幌医科大学 医学部公衆衛生学
-
Toda G
Jikei Univ. School Of Medicine Tokyo Jpn
-
Toda Gotaro
Division Of Gastroenterology And Hepatology Department Of Internal Medicine Daisan Hospital Jikei Un
-
Toda Gotaro
Division Of Gastroenterology And Hepatology Jikei University Hospital
-
銭谷 幹男
Division Of Gastroenterology And Hepatology Department Of Internal Medicine The Jikei University Sch
-
Mori Mitsuru
Department Of Community Health Science Saga Medical School
-
Zeniya M
Division Of Gastroenterology And Hepatology Department Of Internal Medicine Jikei University School
-
Zeniya Mikio
Division Of Gastroenterology And Hepatology Department Of Internal Medicine Jikei University School
-
ZENIYA Mikio
Division of Gastoroenterology and Hepatology, Department of Internal Medicine, JIKEI University School of Medicine
関連論文
- Association of Serum Phytoestrogen Concentration and Dietary Habits in a Sample Set of the JACC Study
- Cytokine Profiles of Hepatitis C Virus Carriers who Show Persistently Normal Aminotransferase Levels (Original)
- Single Nucleotide Polymorphisms in the Interleukin-10 Gene Promoter and Clinical Outcome of Chronic Hepatitis C Virus Infection
- Preventive antitumor activity against hepatocellular carcinoma(HCC) induced by immunization with fusions of dendritic cells and HCC cells in mice
- FRS-094 Difference in the Cut-off Point of Extibated GFR as a Predictor of Cardiovascular Event between Elderly and Non-elderly People(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japa
- FRS-094 Difference in the Cut-off Point of Extibated GFR as a Predictor of Cardiovascular Event between Elderly and Non-elderly People(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japa
- FRS-094 Difference in the Cut-off Point of Extibated GFR as a Predictor of Cardiovascular Event between Elderly and Non-elderly People(Renal Dysfunction and Cardiovascular Disease(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japa
- The efficacy of ursodeoxycholic acid and bezafibrate combination therapy for primary biliary cirrhosis : A prospective, multicenter study
- Diabetes mellitus and kidney cancer risk : The results of Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)
- Risk Factors for Kidney Cancer in a Japanese Population : Findings from the JACC Study
- Dietary Habits and Risk of Urothelial Cancer Incidence in the JACC Study
- Diagnosing clinical subsets of autoimmune liver diseases based on a multivariable model
- 川崎病罹患患者における脈波伝搬速度(PWV)、足首関節/上腕血圧指数(ABI)の検討
- Active Smoking, Passive Smoking, and Breast Cancer Risk : Findings from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk
- Anthropometric and Other Risk Factors for Ovarian Cancer in a Case-Control Study
- Incidence of Hypertension in Individuals with Abdominal Obesity in a Rural Japanese Population : The Tanno and Sobetsu Study
- PJ-778 Accumulation of risk Factors in Individuals with Abdominal Obesity in a Rural Japanese Population : The Tanno and Sobetsu Study(Diabetes/Obesity/Metabolic syndrome-13, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Antimitochondrial Antibody Negative Primary Biliary Cirrhosis in Japan : Utilization of Clinical Data When Patients Applied to Receive Public Financial Aid
- A Cross-Sectional Study of Primary Biliary Cirrhosis in Japan : Utilization of Clinical Data When Patients Applied to Receive Public Financial Aid
- A case-control study of diet and prostate cancer in Japan : possible protective effect of traditional Japanese diet
- Comparison of the Clinical Features of Japanese Patients with Primary Biliary Cirrhosis in 1999 and 2004 : Utilization of Clinical Data When Patients Applied to Receive Public Financial Aid
- Survey for Incidence of Cancer as a Measure of Outcome in the JACC Study
- Serum phytoestrogens and prostate cancer risk in a nested case-control study among Japanese men
- The Smoking Experience of Pupils up to and Including Senior High School Age: a Survey of Non-medical University Students in Heilongjiang Prefecture，China．
- Risk Factors for Kidney Cancer
- Burden Among Family Caregivers of the Frail Elderly with Tumors
- Ethical Issues in Cancer Epidemiology and Disease Susceptibility Genes
- A case-control study on risk factors for scleroderma
- Prevalence of prostatitis-like symptoms in Japanese men : Population-based study in a town in Hokkaido
- Familial Aggregation of Uterine Myomas in Japanese Women
- Flushing Pattern and Idiopathic Avascular Necrosis of the Femoral Head
- Prevalence of the 'a' Determinant Mutant in Japanese Adult HBV Carriers Seropositive for Both HBsAg and Anti-HBs (Original)
- Meta-analysis of Multiple Myeloma and Benzene Exposure
- Immunotherapy using fusions of autologous dendritic cells and tumor cells showed effective clinical response in a patient with advanced gastric carcinoma
- Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by β-catenin/TCF
- Blood Isoflavone Levels during Intake of a Controlled Hospital Diet
- Oral Health Conditions in Patients with Parkinson's Disease
- Lifestyle-Related Risk Factors for Total and Cancer Mortality in Men and Women
- Differences in Lifestyle-related Risk Factors for Death by Occupational Groups; A Prospective Study
- Physiological Levels of Estradiol Correlate with Lipid/Lipoprotein Profiles in Healthy Men
- Body Mass Index and Risk of Cancer in Men and Women
- Factors associated with hepatitis C virus transmission in the area of high incidence of hepatic cancer in Japan
- Leisure Time Physical Activity as a Determinant of Self-Perceived Health and Fitness in Middle-Aged Male Employees
- Management of Irritable Bowel Syndrome
- An experimental study on Nd-YAG laser induced thermotherapy : Its possible application of the laser irradiation for therapy of hepatocellular carcinoma
- P4-11 Connexin 43 expression of the intestinal macrophage in patients with Crohn's disease
- Long-term prognosis of primary biliary cirrhosis (PBC) in Japan and analysis of the factors of stage progression in asymptomatic PBC (a-PBC)
- Association between frequency of amino acid changes in core region of hepatitis B virus (HBV) and the presence of precore mutation in Japanese HBV carriers
- Effect of oral branched chain amino acid supplementation in the late evening on the nutritional state of patients with liver cirrhosis
- Meta-analysis of Multiple Myeloma and Benzene Exposure
- Intrahepatic expression of the co-stimulatory molecules programmed death-1, and its ligands in autoimmune liver disease
- Do DCs influence the antiviral effect of interferon/ribavirin by changing their profile during the therapy?
- New weapon for primary biliary cirrhosis from Japan
- Is anti-pyruvate dehydrogenase complex a predictor of the development of primary biliary cirrhosis?
- An Overview of Genetic Polymorphisms and Pancreatic Cancer Risk in Molecular Epidemiologic Studies
- Relationship of Hobby Activities With Mortality and Frailty Among Community-Dwelling Elderly Adults : Results of a Follow-up Study in Japan
- The relationship between number of natural teeth and oral health behavior in adult Japanese people
- Obesity/Weight Gain and Breast Cancer Risk: Findings From the Japan Collaborative Cohort Study for the Evaluation of Cancer Risk
- Area between the hepatic and heart curves of ^Tc-galactosyl-human serum albumin scintigraphy represents liver function and disease progression for preoperative evaluation in hepatocellular carcinoma patients
- Association of Tubal Sterilization and Induced Abortion with Ovarian Cancer:Meta-analysis of Published Case-control Studies
- Familial Aggregation of Uterine Myomas in Japanese Women.
- Maternal and Other Factors of Cryptorchidism. A Case-control Study in Japan.:A Case-control Study in Japan
- What is a common factor in different areas? : The case of depression among caregivers of the frail elderly in Sapporo and Kochi, Japan
- Primary biliary cirrhosis-Autoimmune hepatitis overlap syndrome : A rationale for corticosteroids use based on a nation-wide retrospective study in Japan
- Acute presentation of autoimmune hepatitis : Does it exist? : A published work review
- Obesity/Weight Gain and Breast Cancer Risk : Findings From the Japan Collaborative Cohort Study for the Evaluation of Cancer Risk
- A demographic description of caregivers in Sapporo Japan : male caregivers are here to stay