A Case Report of Malignant Lymphoma in a Patient with Ulcerative Colitis.

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We report a case of malignant lymphoma in a patient with a 15-year history of ulcerative colitis (UC). A 70-year-old female who was in good health until the age of 55 when she developed UC. Remission state of UC was obtained by oral administration of salicylazosulfapyridine. At age of 70, she developed bilateral cervical lymphnode enlargement. The diagnosis of the biopsied lymphnode was non-Hodgkin's lymphoma (follicular, medium-sized cell type). Chest X-ray films and computed tomography showed mediastinal and hilar lymphadenopathy. <SUP>67</SUP>Ga citrate scan revealed hot area at middle abdominal region. Liver and spleen scan were normal and a bone-marrow aspirate was normal. The clinical stage was regarded as MA. She received three cycles of combination chemotherapy; modified CHOP (cyclophosphamide, THP-adriamycin, vincristine and prednisolone). After the chemotherapy, partial response was obtained. During the period of the chemotherapy, no relapse of UC was observed.
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