Depressor Reflex from the Kidney with Altered Perfusion Pressure
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概要
- 論文の詳細を見る
(1) In anesthetized dogs the kidney was perfused in situ by another dog and the cardiovascular effects of alterations in pressure in the kidney have been investigated.(2) Elevated perfusion pressure with intact renal outflow (mean pressure between 120 and 300mm.Hg) infrequently produced a fall in systemic arterial pressure of the recipient; in 3 out of 9 dogs, systemic pressure decreased more than 10%; in 6 dogs, there was little or no effect.(3) The increment in perfusion pressure with simultaneous occlusion of the renal vein caused systemic hypotension more effectively than without. In this series, a significant lowering in systemic pressure was obtained in the physiological range of perfusion pressure. The effects were ordinarily potentiated by sinus nerve denervation and abolished by splanchnicectomy.(4) It is concluded that minor but reproducible decrease in systemic arterial pressure is reflexly elicited by increasing pressure in the kidney. Renal venous pressure plays an important role in this response.
- International Heart Journal刊行会の論文
著者
-
Ishii Masao
Second Department Of Internaal Medicine Yokohama City University
-
INOUE Gosuke
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
-
YAGI Shigeru
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
-
Ueda Hideo
Second Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
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