Experimental Vascular Lesions Elicited by Collagenase in Rats
スポンサーリンク
概要
- 論文の詳細を見る
Vasculotoxic effect of purified collagenase was investigated in the normal and DCA hypertensive rats.(1) Body weight increased with fluid retention in collagenase treated and DCA-collagenase-treated rats.(2) Blood pressure elevated in the rats given DCA and 1% saline for drink and it decreased slightly after 2 weeks of collagenase treatment.(3) Proteinuria developed in the collagenase-treated and DCA-collagenase-treated rats with decrease in total plasma protein in the latter. No elevation of blood urea nitrogen was recognized.(4) Mild degenerative lesions in the small arteries and arterioles were observed in the collagenase-treated rats. Necrotizing renal and vascular lesions, arteriolar fibrinoid necrosis, glomerular degeneration and perivascular proliferation of collagen fibers were observed in the DCA-collagenase-treated rats which were identical in nature with lesions caused by DCA treatment only but more extensive and severe.(5) These observations suggest that collagenase increases vascular permeability and serves as augmenting or accelerating factor in the development of hypertensive vascular disease.
- International Heart Journal刊行会の論文
著者
-
Yasuda Hisakazu
Second Department Of Internal Medicine Faculty Of Medicine University Of Tokyo:dokkyo Medical Colleg
-
Ueda Hideo
Second Dept. Of Intern. Med. University Of Tokyo School Of Med.
-
NISHIMURA Hiroko
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
-
Ueda Hideo
Second Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
関連論文
- STUDIES ON EXERCISE VECTORCARDIOGRAM WITH FRANK'S LEAD : Proceedings of the 34th Annual Meeting of the Japanese Circulation Society (part III)
- ANALYSIS OF THE ELECTROCARDIOGRAM IN MYOCARDIAL INFARCTION IN TERMS OF THE INSTANTANEOUS INFARCTION VECTOR
- A Theoretical Consideration of T Wave Generation : An Experimental and Clinical Study
- Studies on the Regulation of Circulatory and Respiratory Systems (XVI)
- 81) Changes in Catecholamine and Aldosterone Secretion Following Stimulation of Central Gray Stratum of the Midbrain
- 83) The Reflex Control from the Right Subclavian Baroreceptor on Systemic Blood Pressure in Experimental Hypertension
- HYPERTENSION WITH HYPERRENINEMIA APPARENTLY CAUSED BY DECREASED HEPATIC INACTIVATION OF RENIN : Proceedings of the 34th Annual Meeting of the Japanese Circulation Society (Part II)
- RENAL BIOPSY FINDINGS, DURATION OF HYPERTENSION AND RENIN RELEASE IN PATIENTS WITH ESSENTIAL HYPERTENSION
- 80. Bilateral Renal Venous Renin Activity after Stimulation of Renin Release in Patients with Renovascular Hypertension
- Effect of Hydralazine on Plasma Renin Activity in Hypertensive Patients : Part II
- Effect of Ganglion Blockade on Release of Renin in Man
- EVALUATION OF THE HEMODYNAMIC FACTORS AFFECTING THE CLINICAL SEVERITY OF RHEUMATIC MITRAL VALVULAR DISEASES WITH SPECIAL REFERENCE TO THE LEFT VENTRICULAR ABNORMALITIES IN MITRAL STENOSIS
- PROGNOSIS OF 696 PATIENTS WITH VALVULAR DISEASES, INCLUDING 169 WITH MITRAL STENOSIS EXAMINED BY CARDIAC CATHETERIZATION
- CLINICAL STUDIES ON THE CARDIAC PERFORMANCE BY MEANS OF LEFT HEART CATHETERIZATION (Report 8) : Left Ventricular Function in Cases of Valvular Regurgitation
- 189. Clinical Studies on the Cardiac Performance by Means of Left Heart Catheterization (VII) Cineangiocardiographic Observation of Dyssynergy of Ventricular Contraction in Men
- 37. A Study of Experimental Fusion Beats: with Special Reference to the Ventricular Complex of WPW Syndrome and Atrioventricular Conduction Time
- Add. Horizontal Loop of Hypertensive Subjects
- PHYSIOLOGIC REAPPRAISAL OF SO-CALLED "APICAL" MITRAL MURMURS WITH PARTICULAR REFERENCE TO THE PATTERN OF TRANSMISSION : Proceedings of the 34th Annual Meeting of the Japanese Circulation Society (Part II)
- DIASTOLIC MURMURS IN ATRIAL SEPTAL DEFECT : Intracardiac Phonocardiographic and Hemodynamic Study
- Clinical Study on the Cardiac Function by Means of Trans-septal Left Heart Catheterization (Report 2)
- EFFECT OF ARRHYTHMIA ON LEFT VENTRICULAR FUNCTION : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Clinical Studies on Cardiac Performance by Means of Left and Right Heart Catheterization (6) Hemodynamic Effects of Methoxamine : Part II
- Clinical Studies on Cardiac Performance by Means of Left and Right Heart Catheterization (5) : Hemodynamic Effect of Isoproterenol
- 12) Clincal Studies on the Cardiac Performance by Means of Transseptal Left Heart Catheterization : Report IV Left Ventricular Performance in High Output Heart Diseases
- MYOCARDIAL BLOOD FLOW IN THE HYPERTROPHIED HEART : PROCEEDINGS OF THE 35TH ANNUAL MEETlNG OF THE JAPANESE CIRCULATION SOCIETY (Part III)
- Studies on the Hemodynamics by Means of Radioisotope Dilution Technique with Special Reference to the Analysis of Rapid Circulation Wave
- The Mechanism of Renin Secretion following Electrical Stimulation of the Midbrain : Part II
- Effects of Midbrain Stimulation and Intravenous Infusion of Catecholamine on Renin Secretion
- HETEROGENOUS MYOCARDIAL DISTRIBUTION OF BLOOD FLOW INDUCED BY ISOPROTERENOL : Proceedings of the 34th Annual Meeting of the Japanese Circulation Society (part III)
- 205) Regronal Myocardial Blood Flow Measured by I^131 Labelled Macroaggregated Albumin
- Follow-up Study of Renal Blood Flow in Patients with Essential Hypertension : Changes in Those under Natural Course and under Antihypertensive Treatment
- Studies on Ventilation-Perfusion Relationship using Inhalation and Perfusion Scintiscanning Method
- Two Types of Renal Mechanoreceptors
- Responses of the Cardiac Sympathetic Receptors to Various Substances
- Sympathetic Nerve Activity During Hypertension Produced by Vertebral Embolism
- Unusual Coarctation of the Aorta with a Large Saccular Aneurysm
- Prognostic Implications of Certain Kidney Function Tests in Diffuse Glomerulonephritis
- Two Cases of Complex A-V Interference-Dissociation
- Observations upon Some Aspects of A-V Conduction in Advanced A-V Block
- Precordial-Intracardiac Phonocardiographic Correlative Study of Ventricular Septal Defect
- Interatrial Septal Murmurs in Secundum Type Atrial Septal Defect : Intracardiac Phonocardiographic and Hemodynamic Study
- Reversed Splitting of the Second Heart Sound in Arterial Stenotic Lesions
- Acquired Pulmonary Artery Stenosis Report of a Case Caused by Mediastinal Tumor
- Quadrivalvular Heart Disease An Autopsied Case with Massive Pulmonary Regurgitation
- The Point of Maximum Intensity of Aortic Diastolic Regurgitant Murmur : With Special Reference to the "Right-Sided" Aortic Diastolic Murmur
- QRS Dependence of the Split Interval of the Second Heart Sound in Complete Right and Left Bundle Branch Block
- Better Resolution in Clinical Phonocardiography : II. The Use of Compressor Phonocardiograph
- Better Resolution in Clinical Phonocardiography The Use of Simultaneously Recorded Multi-Filter System Phonocardiograms Synchronously Taken from Various Auscultatory Areas
- Annular Constrictive Pericarditis A Case with Functional Pulmonary and Mitral Stenosis
- Clinical and Pathological Studies of Five Autopsied Cases of Aortitis Syndrome : Part II. Pathological Findings of the Heart, Coronary Artery and Aortic Valve with Reference to Prognosis of Aortitis Syndrome
- Clinical and Pathological Studies of Five Autopsied Cases of Aortitis Syndrome : Part I. Findings of the Aorta and Its Branches, Peripheral Arteries and Pulmonary Arteries
- 268) Effect of Unilateral Pulmonary Artery or Vein Distension by Balloon on Pulmonary Arterial and Femoral Arterial Pressure in Anesthetized Dogs
- 79. The Mechanism of Increased Renin Secretion Caused by Isoproterenol and Norepinephrine
- Circulatory and Respiratory Effects of Hypertonic Saline with Special Reference to the Coronary Effect
- Pulmonary Regional Ventilation-Perfusion Relationships in Chronic Cardiopulmonary Disorders : II. Scintiscanning Method
- Measurement of Hepatic Arterial and Portal Blood Flow and Circulation Time via Hepatic Artery and Portal Vein with Radioisotope
- Analysis of Radioactive Colloidal Gold Uptake Rate in the Liver by Electronic Digital Computer : New Analytical Method for the Determination of Liver Blood Flow
- Experimental Vascular Lesions Elicited by Collagenase in Rats
- Experimental Vascular Lesions in Desoxycorticosterone Hypertension in Rats
- Experimental Production of Ventricular Complex Simulating A, B, and C Types of WPW Syndrome
- Further Immunological Studies of Aortitis Syndrome
- The Current Status of Ischemic Heart Disease and Myocardial Infarction in Japan
- Centrally Mediated Vasopressor Effect of Angiotensin II in Man
- Sympathetic Activity in Cerebral Embolism
- Clinical Observation of 52 Cases of Aortitis Syndrome
- Cineangiocardiographic Observations on the Asynchronism of Cardiac Contraction during Ventricular Pacing
- Two Cases of Aortitis Syndrome with Aneurysm Formation
- Studies with Tritiated Digoxin in Renal Failure and Diabetes Mellitus
- Spatial T Wave Changes Produced by Exercise in Health and Disease
- Reflex Control of Blood Pressure by the Right Subclavian Baroreceptor in Experimental Renal Hypertension of Rabbit
- Effects of Mesencephalic Stimulation on Resistance and Capacitance Vessels in Extremity of the Dog
- Comparison of Vasoconstrictor Responses in Functionally Different Organs Induced by Stimulation of Mesencephalic Pressor Area
- A Vectorcardiographic Study of WPW Syndrome
- Experimental Studies on the Nervous Control of the Renal Circulation : Effect of the Electrical Stimulation of Splanchnic, Vagal and Other Somatic Nerves and of the Carotid Sinus Reflex on the Renal Circulation (II)
- Treatment of Hypertension with KK-25-S, a New Potent Ganglionic Blocking Agent
- Experimental Studies on the Nervous Control of the Renal Circulation-Effect of the Electrical Stimulation of the Diencephalon on the Renal Circulation
- External Measurement of Regional Cerebral Blood Flow in Man by Common Carotid Arterial Injection of Radioactive Krypton-85 Saline Solution
- Idiopathic Cardiomegaly and Endomyocardial Fibrosis
- Afferent Impulses in the Renal Nerves
- Cerebrovascular Lesions in Experimental Renal Hypertensive Rats
- Effects of Diet on Blood Pressure in Experimental Renal Hypertensive Rat
- Some Hemodynamic and Clinico-pathological Consideration of Congestive Heart Failure with Special Reference to Therapeutic Effect
- Precordial Low-frequency Vibrocardiography : II. The Normal Configuration
- A Graphical Method for Evaluation of Narrowing of the Coronary Arteries (Coronary Profile Method)-With Special Reference to Intramural Arteriolosclerosis
- Primary Cardiomyopathy : Clinical Spectrum of Adult Japanese Patients
- A Cineangiocardiographic Study of the Regional Contraction Sequence of the Normal and Diseased Left Ventricle in Man
- Experimental Arteritis Produced Immunologically in Rabbits
- Left Ventricular Performance during the Infusion of Isoproterenol in Patients with Valvular Heart Diseases and Idiopathic Cardiomegaly
- Phonoarteriographic and Arteriographic Evaluation of Abdominal Murmurs in Renovascular Hypertension
- Myocardial Involvement in Benign Duchenne Type of Progressive Muscular Dystrophy
- Increased Renin Release Evoked by Mesencephalic Stimulation in the Dog
- The Acute Effect of Aminophylline on Left Ventricular Function in Patients with Heart Failure : Clinical Studies on the Cardiac Performance by Means of Left Heart Catheterization
- Effects of the Electrical Stimulation of the Central Gray Stratum of the Midbrain on the Blood and Myocardial Catecholamine
- Myocardial Distribution of Blood Flow in the Dog, Studied by the Labeled Microsphere:Part II. Heterogeneity of Myocardial Blood Flow in Left Ventricle Induced by Isoproterenol Injection
- Successive Measurements of Cardiac Output by External Monitoring Using Digital Counter and Automatic Digital Printer
- Myocardial Distribution of Blood Flow in the Dog, Studied by the Labeled Microsphere:Part I. Method
- Clinical Studies on the Cardiac Performance by Means of Transseptal Left Heart Catheterization:The Acute Effects of Digitalis on Left Ventricular Function in Patients with Valvular Stenosis
- Studies on Myocardial Metabolism by Coronary Sinus Catheterization in Man:Relationship of Myocardial Metabolism to ECG and Cardiac Size
- Clinical Studies on the Cardiac Performance by Means of Transseptal Left Heart Catheterization:II. Left Ventricular Function in High Output Heart Diseases, Especially in Hyperthyroidism
- Changes in Coronary Blood Flow by Stimulation of Central Nervous System