Altered Platelet α_2-Adrenoceptors in Patients With Ischemic Heart Disease

スポンサーリンク

概要

• 論文の詳細を見る

• We evaluated the characteristics of platelet α_2-adrenoceptors in 12 patients with effort angina pectoris, 11 patients with variant angina pectoris and 11 normal control subjects. α_2-Adrenoceptors were quantified using a radioligand binding assay with radiolabelled rauwolscine, an α_2-selective antagonist. In addition, plasma norepinephrine concentration were measured by high performance liquid chromatography. The mean value of the maximal number of binding sites(B_<max>)in patients with effort angina(205.1±11.3 fmol/mg protein)was significantly lower than that in control subjects(293.0±10.2 fmol/mg protein). B_<max> did not differ between patients with variant angina(322.9±45.4 fmol/mg protein)and control subjects. There was no significant difference in the dissociation constant(K_d)among the 3 groups. The plasma norepinephrine concentration tended to be higher in patients with effort angina or variant angina than in normal controls, but this difference was not statistically significant. In addition, studies in another group of young volunteers(n=20)revealde a negative correlation(r=0.05, p<0.05)between the B_<max> of^3H-rauwolscine binding to platelets and the percent change in the plasma norepinephrine concentration when subjects moved from the supine to the standing position. This suggests a functional correlation between platelet α_2-adrenoceptors and those located at presynaptic sites. If platelet α_2-adrenoceptors correlate with presynaptic α_2-adrenoceptors, the current findings of decreased α_2-adrenoceptor density in platelets from patients with effort angina could represent attenuated negative feedback of norepinephrine by presynaptic α_2-adrenoceptors.

• 社団法人日本循環器学会の論文
• 1995-09-20

著者

• Uchino Kazuaki

  Department of Cardiorenal Medicine, Yokohama City University Graduate School of Medicien

• Ishii Masao

  Japan Medical Association

• Umemura Satoshi

  Second Department of Internal Medicine, Yokohama City University Hospital

• Ishikawa Yoshihiro

  Cardiovascular Research Institute Yokohama City University Graduate School Of Medicine

• Ishikawa Yosiyuki

  横浜市立大学 循環器内科

• Iizuka Masahiko

  Department Of Radiology Faculty Of Medicine University Of Tokyo

• Ishii Masao

  Department Of Geriatric Medicine Osaka University Graduate School Of Medicine

• Umemura S

  Department Of Internal Medicine And Cardiorenal Medicine Yokohama City University Graduate School Of

• Ishikawa Masahiro

  Department Of Molecular Cardiovascular Biology And Pharmacology Ehime University Graduate School Of

• Uchino Kazuaki

  Department Of Cardiology Sagamihara National Hospital

• Imanishi Masahito

  Department Of Internal Medicine

• Ishii M

  Japan Medical Association

• OCHIAI HISAO

  Second Department of Internal Medicine, Yokohama City University, School of Medicine

• ISHII Masao

  Second Department of Internal Medicine, School of Medicine, Yokohama City University

• Ishii Masao

  Department Of Radiology Faculty Of Medicine University Of Tokyo

• Ochiai Hisao

  Second Department Of Internal Medicine Yokohama City University

• Ikeda Yasuhiro

  Cardiovascular Research Institute Yokohama City University Graduate School Of Medicine

• ISHII Masao

  Research Group on Evaluation of the Effects of Drug Treatment on Hypertension and Other Disease Cond

• Umemura Satoshi

  Second Department Of Internal Medicine Yokohama City University School Of Medicine

• Inayama Yoshiaki

  Cardiovascular Research Institute Yokohama City University Graduate School Of Medicine

• Ishikawa Yoshihiro

  Cardiovascular Research Institute Yokohama City University

• Nihei Tohyoh

  Second Department Of Internal Medicine Yokohama City University School Of Medicine

• Ishii Masao

  Second Department Of Internal Medicine School Of Medicine Yokohama City University

• Mitani Isao

  Department Of Pediatric Cardiology Yokohama City University Hospital

• Ishii Masao

  University Of Tokyo Second Dept. Of Internal Medicine

• Ishikawa Yoshihiro

  Second Department of Internal Medicine, Yokohama City University School of Medicine

• Ishii Masao

  Second Department Of Internal Medicine Yokohama City University School Of Medicine

• Iio Masahiro

  The Department Of Radiolocrv Universitv Of Tokyo

• Ishii M

  Department Of Gene Diagnostics And Therapeutics Research Institute National Center For Global Health

• Ishii Masao

  Second Department Of Internaal Medicine Yokohama City University

• Ishikawa Yoshihiro

  Department Of Physiology Yokohama City University

関連論文

• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension
• OE-061 Cardiorenal Relationship-A role of Na channel-Nedd4L-proteasome system for essential hypertension and angiotensin II (All) induced transcriptional changes in cardiomyocyte.(Hypertension, basic(01)(H),Oral Presentation(English),The 72nd Annual Scien
• NEDD4L protein truncating variant (v13[G/A] : rs4149601) is associated with essential hypertension in a sample of the Japanese population
• Long-Term Electrocardiographic Follow-up From Childhood of an Adult Patient With Brugada Syndrome Associated With Sick Sinus Syndrome : A Case Report
• Novel Method of Predicting the Optimal Atrioventricular Delay in Patients With Complete AV Block, Normal Left Ventricular Function and an Implanted DDD Pacemaker
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• Left ventricular geometry, risk factors, and outcomes of hospitalized patients with diastolic heart failure in Japan
• A case of giant coronary artery aneurysm and literature review
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• Efficacy of Consistent Atrial Pacing Algorithm for Suppression of Atrial Arrhythmias in Patients With Sick Sinus Syndrome and Atrial Fibrillation
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• PJ-376 Bone Marrow AT1 and AT2 Differentially Modulate Vascular Repair by Regulating Mobilization of Bone Marrow-derived c-Kit^-Sca-1^+Lin^- Progenitors via SDF-1 α/CXCR4 Axis(Restenosis basic/clinical(04)(IHD),Poster Session(Japanese),The 72nd Annual Sci
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• Matrix Metalloprpteinas-2 Levels Changes May Predict Restenosisafter PTCA
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• IS040 Positive association between essential hypertension and Glu298Asp polymorphism in the endothelial nitric oxide synthase gene
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• PJ-283 Severely Impaired Left Ventricular Ejection Fraction is a Risk Factor of Pulmonary Toxicity in Patients with Long-term Administration of Amiodarone(PJ048,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (Japanese),The 73rd Ann
• 2 Long-term Clinical Outcome after Intramuscular Implantation of Bone Marrow Mononuclear Cells (TACT Trial) in Patients with Chronic Limb Ischemia(Regenerative Therapy for Peripheral Artery Disease,Symposium 12 (SY-12) (I),The 73rd Annual Scientific Meeti
• PJ-635 Effect of Olmesartan on Tissue Expression Balance between Angiotensin II Receptor and Its Inhibitory Binding Molecule(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
• Nifedipine Retard Was as Effective as Angiotensin Converting Enzyme Inhibitors in Preventing Cardiac Events in High-Risk Hypertensive Patients with Diabetes and Coronary Artery Disease : The Japan Multicenter Investigation for Cardiovascular Diseases-B (J
• PJ-643 Tissue-Specific Regulation of ATRAP, A Novel Interacting Molecule with AT1 Receptor, in Spontaneously Hypertensive Rats(Hypertension, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• ACE2 Mutant Mice Increase Cardiac Angiotensin II and Increase Incidence of Heart Failure in Response to Pressure Overload (Heart Failure, Basic 7 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Aspirin Renography in Diagnosis of Unilateral Renovascular Hypertension
• PJ-219 Novel Method of Predicting Optimal Atrioventricular Delay using Phonocardiogram in Patients with Cardiac Resynchronization Therapy(Arrhythmia, therapy(24)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation So
• PJ-380 Prevalence of Sleep Disorderd Breathing and Effect of Biventricular Pacing in Patients with Heart Failure(Heart failure, clinical-11, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• 3 Assessment of Regional Wall Motion during Pacing Therapy using Strain Doppler Image(Identification Strategy and Treatment Approach of the Non-responder Group in Patients Withcardiac Resynchronization Therapy using biventricular Pacing, The 71st Annual S
• Reverse Perfusion-Metabolism Mismatch Predicts Good Prognosis in Patients Undergoing Cardiac Resynchronization Therapy : A Pilot Study
• Daily Shock Impedance Measured by Implantable Cardioverter Defibrillator is Useful in the Management of Congestive Heart Failure
• Suppression of Atrial Fibrillation by Atrial Pacing
• PJ-461 Daily Shock Impedance Measured by Implantable Cardioverter Defibrillator is Useful in the Management of Congestive Heart Failure(Arrhythmia, therapy-16 (A) PJ78,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanes
• Changes of Sympathetic Activity in Patient with Chronic Atrial Fibrillation and Severe Congestive Heart Failure Treated with Biventricular Pacing
• Inverse Relation between Condition of Heart Failure and Intrathoracic Impedance Measured by Implantable Cardioverter Defibrillator : A case report
• The Assessment of Inter-atrial Contraction Delay by Using Strain Doppler Imaging(Arrhythmia, Diagnosis/Pathophysiology/EPS 11 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Prevalence of Right Bundle-Branch Block and Right Precordial ST-Segment Elevation (Brugada-Type Electrocardiogram) in Japanese Children
• PJ-204 Assessment of regional wall motion of atrium during biatrial pacing using Strain Doppler Imaging(Arrhythmia, Non-Pharmacological Therapy 7 (A) : PJ34)(Poster Session (Japanese))
• FRS-119 The Benefit of Biventricular Pacing on Glucose Metabolism, Perfusion and Wall Thickening Assessed By Gated FOG-PET and Gated MIBI SPECT(Nuclear Cardiology (I) : FRS14)(Featured Research Session (English))
• Benefical Effects of Biatrial Pacing for Cardiac Function
• PJ-131 Bone Marrow AT1 and AT2 Modulate Vascular Repair by Regulating Mobilization and Differentiation of Vascular Progenitor Cells and Macrophage Activation(Restenosis basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulation Socie
• OJ-026 Angiotensin II Type2 Receptor in Bone Marrow-Derived Cells Inhibits Neointimal Hyperplasia by Counteracting Type1 Receptor Function in Mouse Wire-Injured Artery(Restenosis, basic/clinical-1 (IHD) OJ5,Oral Presentation (Japanese),The 70th Anniversar
• A randomized open-label comparative study of conventional therapy versus mizoribine onlay therapy in patients with steroid-resistant nephrotic syndrome (postmarketing survey)
• Circadian Variation of Hemodynamics and Baroreflex Functions in Patients with Essential Hypertension
• Doxazosin Suppresses the Morning Increase in Blood Pressure and Sympathetic Nervous Activity in Patients with Essential Hypertension
• 0993 HEMODYNAMICS IN PATIENTS WITH ESSENTIAL HYPERTENSION CLASSIFIED ON THE BASIS OF DAYTIME BLOOD PRESSURE INCREASE RATE
• -1035- CIRCADIAN VARIATION IN AUTONOMIC NERVOUS FANCTION EVALUATED BY THE CHANGES OF HEMODYNAMICS IN PATIENTS WITH ESSENTIAL HYPERTENSION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• Factors Related to Impairment of Activities of Daily Living
• 0322 SMOKING IMPAIRS ADL (ACTIVITIES OF DAILY LIVING)
• Current Status of Antihypertensive Therapy for Elderly Patients in Japan
• Association between senescence-related uncoupling protein 2 gene polymorphisms and abdominal obesity in Japanese subjects : The Tanno and Sobetsu study
• Increase in Pulse Pressure Relates to Diabetes Mellitus and Low HDL Cholesterol, but Not to Hyperlipidemia in Hypertensive Patients Aged 50 Years or Older
• Control of Blood Pressure and Lifestyle-Related Risk Factors in Elderly Japanese Hypertensive Subjects
• OE-276 Transcriptional Regulation of Human Nedd4L Gene Isoform I and Development of Essential Hypertension(Hypertension, basic-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• ARBs or ACEIs, That Is the Question
• OE-274 A Novel Interacting Molecule with C-terminal of AT1 Receptor as a Potential Modulator of Cardiomyocyte Hypertrophy(Hypertension, basic-1 (H) OE46,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
• Long-term Effects of Nifedipine Retard vs ACE Inhibitors in Hypertension with Coronary Artery Disease : Final Reports of J-MIC(B)
• IS049 Implication of cardiotrophin-1 in myocyte-nonmyocyte interaction during cardiac hypertrophy in vitro
• Effects of Renin-Angiotensin System Blockade and Dietary Salt Intake on Left Ventricular Hypertrophy in Dahl Salt-Sensitive Rats
• -0958- Age Dependent Increase in Plasma Angiotensinogen and Enhanced Expression of Angiotensinogen mRNA in Heart and Aorta of Wistar Fatty Hypertensive Rats(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• -0704- Salt Depletion with Renin-Angiotensin System Blockade Markedly Regressed Left Ventricular Hypertrophy in Dahl Salt-Sensitive Rats(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• EFFECTS OF ANGIOTENSIN II RECEPTOR ANTAGONISTS,LISARTAN AND TCV 116, ON CARDIOVASCULAR HYPERTROPHY IN SALTLOADED DAHL SALT-SENSETIVE RATS
• ECHOCARDIOGRAPHIC ASSESSMENT OF THE EFFECTS OF SHORT-TERM TREATMENT WITH CERONAPRIL(SQ-29,852)ON CARDIAC FUNCTION IN PATIENTS EITH ESSENTIAL HYPERTENSION
• PJ-120 Nifedipine Retard and ACE Inhibitors Did Not Show the Similar Relationship between Cardiac Events and Achieved Systolic Blood Pressure(Hypertension, Clinical 2 (H) : PJ20)(Poster Session (Japanese))
• OJ-249 Long-term Efficacy of Nifedipine Retard and ACE Inhibitors in Diabetic Patients with Hypertension and Coronary Artery Disease : JMIC-B Subgroup analysis(Hypertension, Clinical 5 (H) : OJ29)(Oral Presentation (Japanese))
• Comparison of Nifedipine Retard with Angiotensin Converting Enzyme Inhibitors in Japanese Hypertensive Patients with Coronary Artery Disease : The Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) Randomized Trial
• Developmental Changes in Expression of Angiotensinogen mRNA in Rat Nephron Segments
• Effect of Right Atrial Pacing Preference for the Prevention of Paroxysmal Atrial Fibrillation : Atrial Pacing Preference Study (APP Study)(Arrhythmia, Non-pharmacological Therapy 2 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Societ
• Long-Term Course and Clinical Characteristics of Ventricular Tachycardia Detected in Children by School-Based Heart Disease Screening
• OJ-172 Assesment of Ventricular Tortional Deformation in Single Right Ventricle by Two-Dimensional Ultrasound Speckle Tracking Imaging(Echo/Doppler-4 (I) OJ29,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circ
• Klotho gene delivery suppresses oxidative stress in vivo
• The Impact of Body Mass Index on Clinical and Angiographical Characteristics in Female Patients with Acute Myocardial Infarction
• -P489- THE CORRELATION BETWEEN THE CHANGES IN CORONARY ARTERY FLOW AND THE CHANGES IN THE R-R DURATION-DIASTOLIC PRESSURE PRODUCT(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• -1117- Clinical Featuers Of Acute Myocaldial Infarction Who Were Administered Ca-Antagonists(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• Hemodynamic Factors Regulating Blood Pressure During Sleep in Patients With Mild Essential Hypertension
• -0540-RELATIONSHIP BETWEEN HEMODYNAMICS AND 24-HR BLOOD PRESSURE PROFILES IN MILD ESSENTIAL HYPERTENSIVE PATIENTS : DEVELOPMENT OF A NEW NONINVASIVE DEVICE FOR MEASURING CARDIAC OUTPUT
• Candesartan and Amlodipine Reduced the High Linearity and Increased the Low Linearity of Cardiovascular Regulation in Spontaneously Hypertensive Rats
• PQ INTERVAL AND DIASTOLIC MITRAL REGURGITATION DURING ATRIAL PACING IN PATIENTS WITH SICK SINUS SYNDROME
• ATRAP May Inhibit Cardiomyocyte Hypertrophy through the p38-MAPK Pathway (Molecular Biology, Myocardium 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-521 The Angiotensin II Type 1 (AT1) Receptor-Associated Protein, ATRAP, strictly regulates AT1 Receptor-Mediated Signaling in Cardiac Myocytes(Molecular Biology, Myocardium 2 (M) : OJ64)(Oral Presentation (Japanese))
• Tolerability and Safety of a Calcium Channel Blocker in Comparison with a Diuretic in the Treatment of Elderly Ptients with Hypertension : Secondary Analysis of the NICS-EH
• IS108 Molecular mechanism of cyclic stretch-mediated activation of fibronectin gene in vascular smooth muscle cells
• Tubular RAS(Renin-Angiotensin System)-Its Implications for Pathogenesis and Development of Essential Hypertension(EH)(Hypertension, Basic 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Acute Eosinophilic Myocarditis in a Young Woman
• Clinical value of I-123 BMIPP myocardium SPECT for predicting the cardiac death among the patients of chronic heart failure
• Utility and feasibility of a new programmable home blood pressure monitoring device for the assessment of nighttime blood pressure
• Altered Platelet α_2-Adrenoceptors in Patients With Ischemic Heart Disease

もっと見る 閉じる

スポンサーリンク