OJ-026 Angiotensin II Type2 Receptor in Bone Marrow-Derived Cells Inhibits Neointimal Hyperplasia by Counteracting Type1 Receptor Function in Mouse Wire-Injured Artery(Restenosis, basic/clinical-1 (IHD) OJ5,Oral Presentation (Japanese),The 70th Anniversar
スポンサーリンク
概要
- 論文の詳細を見る
- 社団法人日本循環器学会の論文
- 2006-03-01
著者
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Matsubara Hiroaki
Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine
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Horiuchi Masatsugu
Department of Medical Biochemistry 1, Ehime University School of Medicine
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ITO Masaaki
Mie University
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URA Nobuyuki
Teine Keijinkai Hospital
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Ishii Masao
Japan Medical Association
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takahashi tomosaburo
Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine
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Tsubakimoto Yoshinori
Department of Cardiolgy, Kyoto Prefectural University of Medicine
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Okigaki Mitsuhiko
Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine
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Takahashi Tomosaburo
Department Of Cardiovascular Medicine Kyoto Prefectural University School Of Medicine
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YAMADA Hiroyuki
Department of Materials Engineering, Graduate school of Engineering, The University of Tokyo
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Yokoi Hirokazu
Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine
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Maekawa Taira
Transfusion Medicine and Cell Therapy, Kyoto University Hospital
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Urao Norifumi
Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine
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Ashihara Eishi
Department of Transfusion Medicine and Cell Therapy (E.A., T.M.), Kyoto University Hospital
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Maekawa Taira
Department of Transfusion Medicine and Cell Therapy (E.A., T.M.), Kyoto University Hospital
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Iwai Masaru
Department of Molecular Cardiovascular Biology and Pharmacology, Ehime University Graduate School of
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Ashihara Eishi
京都府立医科大学 医学部医学科内科学教室血液･腫瘍内科学
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Ashihara Eishi
Department Of Transfusion Medicine And Cell Therapy (e.a. T.m.) Kyoto University Hospital
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Ashihara Eishi
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto Prefectural University Of Me
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Maekawa Taira
京都府立医科大学 医学部医学科内科学教室血液･腫瘍内科学
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Maekawa Taira
Department Of Transfusion Medicine And Cell Therapy (e.a. T.m.) Kyoto University Hospital
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Maekawa Taira
Jr大阪鉄道病院 血液内分泌内科
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Ura Nobuyuki
Second Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Iizuka Masahiko
Department Of Radiology Faculty Of Medicine University Of Tokyo
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Ishii Masao
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
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Okigaki Mitsuhiko
京都府立医科大学 循環器･腎臓内科学
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Okigaki Mitsuhiko
Department Of Cardiovascular Medicine Kyoto Prefectural University Of Medicine
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Yokoi Hirokazu
Department Of Cardiovascular Medicine Kyoto Prefectural University School Of Medicine
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Tsubakimoto Yoshinori
Department Of Cardiolgy Kyoto Prefectural University Of Medicine
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Iwai Masaru
Department Of Medical Biochemistry Ehime University School Of Medicine
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Takahashi Tomosaburou
Department Of Cardiovascular Medicine Kyoto Prefectural University School Of Medicine
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Matsubara Hiroaki
Department Of Cardiology Kyoto Prefectural University Of Medicine
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Ishikawa Masahiro
Department Of Molecular Cardiovascular Biology And Pharmacology Ehime University Graduate School Of
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Imanishi Masahito
Department Of Internal Medicine
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Okigaki Mitsuhiko
Division Of Hypertension And Nephrology Department Of Internal Medicine Kyoto Prefectural University
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Ura Nobuhuki
Second Department Of Internal Medicine Sapporo Medical University School Of Medicine
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ISHIDA Masashi
St. Therese Hospital
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Ishii Masao
Department Of Radiology Faculty Of Medicine University Of Tokyo
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Iizuka Masahiko
The Second Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
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Imai Masaki
Department Of Internal Medicine Keio University School Of Medicine
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Horiuchi Masatsugu
Department Of Biochemistry Ehime University School Of Medicine
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ISHII Masao
Research Group on Evaluation of the Effects of Drug Treatment on Hypertension and Other Disease Cond
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Urao Norifumi
Department Of Cardiology Kyoto Prefectural Yosanoumi Hospital
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TAKADA YASUHARU
Saijo Central Hospital
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Yokoi Hirokazu
Department Of Cardiology Kyoto Prefectural Yosanoumi Hospital
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Tarutani Yasuhiro
Department Of Cardiology Kohka Public Hospital
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Ishii Masao
The Department Of Radiolocrv Universitv Of Tokyo
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Okigaki Mitsuhiko
Division Of Nephrology And Hypertension Department Of Internal Medicine Kyoto Prefectural University
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Yamada Hiroyuki
Department Of Cardiovascular Medicine Kyoto Prefectural University Of Medicine
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Ishii Masao
University Of Tokyo Second Dept. Of Internal Medicine
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Ishii Masao
Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Ishii Masao
Division Of Second Internal Medicine Yokohama City University School Of Medicine
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Iio Masahiro
The Department Of Radiolocrv Universitv Of Tokyo
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Iio Masahiro
Ii Division Department Of Internal Medicine Tokyo University
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Okigaki Mitsuhiko
Department Of Medicine Ii Kansai Medical University
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Ishii M
Department Of Gene Diagnostics And Therapeutics Research Institute National Center For Global Health
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Takahashi Tomosaburo
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto Prefectural University Of Me
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Ishii M
University Of Tokyo Second Dept. Of Internal Medicine
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Yamada Hiroyuki
Department Of Anatomy School Of Dentistry Aichi-gakuin University
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Matsubara Hiroaki
Department Of Bioscience National Cardiovascular Center Research Institute
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- PJ-117 FGF Receptor Signals in Endothelial Cells Aggravates High Cholesterol Diet-Mediated Atherosclerosis through Dysfunction of Endothelial Cell and VSMC Proliferation(PJ020,Atherosclerosis, Basic 1 (IHD),Poster Session (Japanese),The 73rd Annual Scient
- PE-460 Prehospital Delay Time and the Rate of Ambulance User for Acute Myocardial Infarction were not Improved from 2000-2007 in Kyoto(PE077,ACS/AMI (Clinical/Diagnosis) 1 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese C
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- PJ-335 Cell Therapy Improves Cardiac Dyssynchrony and Reduces the Transmural Extent of the Ischemic Regions in Chronic Myocardial Infarction(PJ057,Translational Science (Cardiac) (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japa
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- PJ-273 A novel but evolutionarily conserved muscle-restricted coiled-coil protein, MURC, regulates myogenic differentiation in C2C12 cells(Development and differentiation(02)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese C
- PE-335 A Novel Muscle-restricted Coiled-coil Protein, MURC, Induces Cardiac Dysfunction Accompanied with an Altered Gene Expression Profile(Heart failure, basic(03)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation
- 3 Human cardiac stem cell biotherapy Integrated with bFGF controlled-release : Two randomized, dose-ranging, controlled preclinical trial(Symposium 12 (SY-12) (M) Clinical Experiences of Regenerative Medicine in Cardiovascular Diseases,Special Program,The
- OJ-133 Calcium-Dependent Tyrosine-Kinase PYK2 Plays Crucial Role in Angiotensin II- but Not Norepineprine-Mediated Activation of Rac/Superoxide-Pathway that Differentially Regulates Blood Pressure(OJ23,Hypertension, Basic (H),Oral Presentation (Japanese),
- OJ-058 Bone Marrow AT1 Receptor Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitor Cells in a Platelet-Derived SDF-1α-Dependent Manner(OJ10,Atherosclerosis, Basic (IHD),Oral Presentation (Japanese),The 73rd Annual Scientifi
- OE-232 Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte/Macrophage-Lineage Progenitors from Hematopoietic Stem Cells(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japane
- OE-055 Ca2+/Redox-Sensitive Tyrosine Kinase PYK2 Promotes Atherogenesis through OxLDL/ROS/p21-Dependent Premature Senescence and Cytokine Induction in Endothelium(OE10,Atherosclerosis, Basic 1 (IHD),Oral Presentation (English),The 73rd Annual Scientific M
- OJ-133 Calcium-Dependent Tyrosine-Kinase PYK2 Plays Crucial Role in Angiotensin II- but Not Norepineprine-Mediated Activation of Rac/Superoxide-Pathway that Differentially Regulates Blood Pressure(OJ23,Hypertension, Basic (H),Oral Presentation (Japanese),
- OJ-058 Bone Marrow AT1 Receptor Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitor Cells in a Platelet-Derived SDF-1α-Dependent Manner(OJ10,Atherosclerosis, Basic (IHD),Oral Presentation (Japanese),The 73rd Annual Scientifi
- OE-232 Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte/Macrophage-Lineage Progenitors from Hematopoietic Stem Cells(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japane
- OE-055 Ca2+/Redox-Sensitive Tyrosine Kinase PYK2 Promotes Atherogenesis through OxLDL/ROS/p21-Dependent Premature Senescence and Cytokine Induction in Endothelium(OE10,Atherosclerosis, Basic 1 (IHD),Oral Presentation (English),The 73rd Annual Scientific M
- PJ-616 Mild Renal Dysfunction Accelerated Atherosclerotic Development by Augmenting Mobilization of Bone Marrow Monocyte-lineage progenitors from Bone Marrow via CCR2-Mediated Signals(Atherosclerosis, basic(08)(IHD),Poster Session(Japanese),The 72nd Annua
- PJ-540 Calcium-dependent-tyrosine-kinase PYK2 Plays Crucial Roles in Angiotensin-II- But Not Norepineprine- Mediated Activation of Rac/ Superoxide Pathway That Differentially Regulates Blood-Pressure(Molecular biology, vascular(02)(IHD),Poster Session(Jap
- PJ-376 Bone Marrow AT1 and AT2 Differentially Modulate Vascular Repair by Regulating Mobilization of Bone Marrow-derived c-Kit^-Sca-1^+Lin^- Progenitors via SDF-1 α/CXCR4 Axis(Restenosis basic/clinical(04)(IHD),Poster Session(Japanese),The 72nd Annual Sci
- OE-416 Novel Action of Angiotensin AT1 Receptor on Bone Marrow Stem Cells, Promotion of Monocyte/Macrophage Lineage Differentiation from Hematopoietic Stem Cells.(Atherosclerosis, clinical(02)(IHD),Oral Presentation(English),The 72nd Annual Scientific Mee
- FRS-030 Calclum/Redox-dependent Tyrosine Kinase PYK2 Promotes Atherogenesis by Inducing Monocyte/Macrophage-Derived TNF-alpha and MCP-1 Unmasked by Analysis of PYK2/ApoE Double Deficient Mice(Novel Mechanisms in Atherosclerosis (IHD),Featured Research Ses
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- 5 Cardiac Regenerative Hybrid-therapy Integrated via Human Autologous Cardiac Stem Cell and Biodegradable bFGF-incorporating Gelatin Hydrogel(Therapeutic Strategy for Severe Heart Failure-From LVAD to Heart Transplantation-,Symposium 11 (SY-11) (H),The 73
- PJ-273 A novel but evolutionarily conserved muscle-restricted coiled-coil protein, MURC, regulates myogenic differentiation in C2C12 cells(Development and differentiation(02)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese C
- PE-335 A Novel Muscle-restricted Coiled-coil Protein, MURC, Induces Cardiac Dysfunction Accompanied with an Altered Gene Expression Profile(Heart failure, basic(03)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation
- 3 Human cardiac stem cell biotherapy Integrated with bFGF controlled-release : Two randomized, dose-ranging, controlled preclinical trial(Symposium 12 (SY-12) (M) Clinical Experiences of Regenerative Medicine in Cardiovascular Diseases,Special Program,The
- OE-232 Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte/Macrophage-Lineage Progenitors from Hematopoietic Stem Cells(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japane
- FRS-030 Calclum/Redox-dependent Tyrosine Kinase PYK2 Promotes Atherogenesis by Inducing Monocyte/Macrophage-Derived TNF-alpha and MCP-1 Unmasked by Analysis of PYK2/ApoE Double Deficient Mice(Novel Mechanisms in Atherosclerosis (IHD),Featured Research Ses
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- OE-232 Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte/Macrophage-Lineage Progenitors from Hematopoietic Stem Cells(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japane
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- PJ-472 Ca2+dependent Tyrosine-kinase Pyk2 Plays Critical Role in Atherogenesis by Inducing Macrophage-derived IL-1β and MCP-1 Unmasked by Analysis of PYK2/ApoE-deficient Mice(Atherosclerosis, basic-5 (H) PJ80,Poster Session (Japanese),The 70th Anniversary
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- OE-232 Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte/Macrophage-Lineage Progenitors from Hematopoietic Stem Cells(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japane
- FRS-030 Calclum/Redox-dependent Tyrosine Kinase PYK2 Promotes Atherogenesis by Inducing Monocyte/Macrophage-Derived TNF-alpha and MCP-1 Unmasked by Analysis of PYK2/ApoE Double Deficient Mice(Novel Mechanisms in Atherosclerosis (IHD),Featured Research Ses
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- PJ-275 Overexpression of Tie2-promoted Activated Fibroblast Growth Factor Receptor-2 in Endothelial Cells Enhances Angiogenesis via Akt Signaling in Mice Hindlimb Ischemia(Regeneration (angionenesis/myocardial regeneration)-8 (M) PJ47,Poster Session (Japa
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- Inhibition of Inward Rectifier K^+ Currents by Angiotensin II in Rat Atrial Myocytes : Lack of Effects in Cells from Spontaneously Hypertensive Rats
- Effects of Angiotensin II on the Action Potential Durations of Atrial Myocytes in Hypertensive Rats
- Predictors of In-Hospital Prognosis After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction Requiring Mechanical Support Devices
- Fatal Splenic Laceration in a Young Woman Caused by Idiopathic Isolated Splenic Vein Thrombosis
- Analysis of Circulating Apoptosis Mediators and Proinflammatory Cytokines in Patients With Idiopathic Hypertrophic Cardiomyopathy : Comparison Between Nonobstructive and Dilated-Phase Hypertrophic Cardiomyopathy
- Transradial Renal Artery Angioplasty and Stenting in a Patient With Leriche Syndrome
- Interventional Treatment for Very Young Adults With Acute Myocardial Infarction : Clinical Manifestations and Outcome
- A Case of Deep Venous Thrombosis With a Double Inferior Vena Cava Effectively Treated by Suprarenal Filter Implantation
- PJ-335 Cell Therapy Improves Cardiac Dyssynchrony and Reduces the Transmural Extent of the Ischemic Regions in Chronic Myocardial Infarction(PJ057,Translational Science (Cardiac) (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japa
- 5 Cardiac Regenerative Hybrid-therapy Integrated via Human Autologous Cardiac Stem Cell and Biodegradable bFGF-incorporating Gelatin Hydrogel(Therapeutic Strategy for Severe Heart Failure-From LVAD to Heart Transplantation-,Symposium 11 (SY-11) (H),The 73
- 3 Human cardiac stem cell biotherapy Integrated with bFGF controlled-release : Two randomized, dose-ranging, controlled preclinical trial(Symposium 12 (SY-12) (M) Clinical Experiences of Regenerative Medicine in Cardiovascular Diseases,Special Program,The
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- PJ-713 Seasonal Mortality Variation in Out-of-hospital Cardiac Arrest : Analysis from AMI-Kyoto Multi-Center Risk Study Database(PJ120,Cardiopulmonary and Critical Care/ACLS (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese
- PJ-588 Rehabilitation after Angiogenic Cell Therapy for the Critical Limb Ischemia(PJ099,Exercise Test/Cardiac Rehabilitation 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
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- PJ-383 Predictors of In-Hospital Prognosis after Primary Percutaneous Coronary Intervention for Repeat Myocardial Infarction : Insights from the AMI-Kyoto Multi-Center Risk Study(PJ065,ACS/AMI (Clinical/Treatment) 3 (IHD),Poster Session (Japanese),The 73r
- PJ-117 FGF Receptor Signals in Endothelial Cells Aggravates High Cholesterol Diet-Mediated Atherosclerosis through Dysfunction of Endothelial Cell and VSMC Proliferation(PJ020,Atherosclerosis, Basic 1 (IHD),Poster Session (Japanese),The 73rd Annual Scient
- PE-460 Prehospital Delay Time and the Rate of Ambulance User for Acute Myocardial Infarction were not Improved from 2000-2007 in Kyoto(PE077,ACS/AMI (Clinical/Diagnosis) 1 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese C
- PE-448 Hypoxia-Induced p53 Deteriorates Cardiac Energetics and Apoptotic Cell Death via TIGAR (TP53-Induced Glycolysis and Apoptosis Regulator)(PE075,Heart Failure (Pathophysiology) (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Ja
- PE-394 p53 and SCO2 (Synthesis of Cytochrome c Oxidase 2) Augment the Progression of Diabetic Cardiomyopathy(PE066,Diabetes 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-133 Calcium-Dependent Tyrosine-Kinase PYK2 Plays Crucial Role in Angiotensin II- but Not Norepineprine-Mediated Activation of Rac/Superoxide-Pathway that Differentially Regulates Blood Pressure(OJ23,Hypertension, Basic (H),Oral Presentation (Japanese),
- OJ-058 Bone Marrow AT1 Receptor Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitor Cells in a Platelet-Derived SDF-1α-Dependent Manner(OJ10,Atherosclerosis, Basic (IHD),Oral Presentation (Japanese),The 73rd Annual Scientifi
- PJ-713 Seasonal Mortality Variation in Out-of-hospital Cardiac Arrest : Analysis from AMI-Kyoto Multi-Center Risk Study Database(PJ120,Cardiopulmonary and Critical Care/ACLS (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese
- PJ-461 Aerobic Exercise in the Postoperative Cardiac Rehabilitation did not Deteriorate Renal Function in the Patients with Renal Failure(PJ078,Kidney/Renal Circulation/CKD 4 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese
- PJ-383 Predictors of In-Hospital Prognosis after Primary Percutaneous Coronary Intervention for Repeat Myocardial Infarction : Insights from the AMI-Kyoto Multi-Center Risk Study(PJ065,ACS/AMI (Clinical/Treatment) 3 (IHD),Poster Session (Japanese),The 73r
- PJ-117 FGF Receptor Signals in Endothelial Cells Aggravates High Cholesterol Diet-Mediated Atherosclerosis through Dysfunction of Endothelial Cell and VSMC Proliferation(PJ020,Atherosclerosis, Basic 1 (IHD),Poster Session (Japanese),The 73rd Annual Scient
- PE-460 Prehospital Delay Time and the Rate of Ambulance User for Acute Myocardial Infarction were not Improved from 2000-2007 in Kyoto(PE077,ACS/AMI (Clinical/Diagnosis) 1 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese C
- PE-448 Hypoxia-Induced p53 Deteriorates Cardiac Energetics and Apoptotic Cell Death via TIGAR (TP53-Induced Glycolysis and Apoptosis Regulator)(PE075,Heart Failure (Pathophysiology) (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Ja
- OJ-133 Calcium-Dependent Tyrosine-Kinase PYK2 Plays Crucial Role in Angiotensin II- but Not Norepineprine-Mediated Activation of Rac/Superoxide-Pathway that Differentially Regulates Blood Pressure(OJ23,Hypertension, Basic (H),Oral Presentation (Japanese),
- OJ-058 Bone Marrow AT1 Receptor Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitor Cells in a Platelet-Derived SDF-1α-Dependent Manner(OJ10,Atherosclerosis, Basic (IHD),Oral Presentation (Japanese),The 73rd Annual Scientifi
- PJ-713 Seasonal Mortality Variation in Out-of-hospital Cardiac Arrest : Analysis from AMI-Kyoto Multi-Center Risk Study Database(PJ120,Cardiopulmonary and Critical Care/ACLS (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese
- PJ-383 Predictors of In-Hospital Prognosis after Primary Percutaneous Coronary Intervention for Repeat Myocardial Infarction : Insights from the AMI-Kyoto Multi-Center Risk Study(PJ065,ACS/AMI (Clinical/Treatment) 3 (IHD),Poster Session (Japanese),The 73r
- PE-460 Prehospital Delay Time and the Rate of Ambulance User for Acute Myocardial Infarction were not Improved from 2000-2007 in Kyoto(PE077,ACS/AMI (Clinical/Diagnosis) 1 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese C
- FRS-036 In-hospital Prognostic Value of Crude Peak Creatine Kinase Measurement after Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction(FRS8,Novel Biomarkers and Pathophysiology of ACS (IHD),Featured Research Session (English),The
- OJ-204 Diminished Relation Between Hospital Volume of Primary PCI and In-Hospital Outcomes After AMI : Insights from the AMI-Kyoto Multi-Center Risk Study(Acute myocardial infarction, clinical (diagnosis / treatment)(04)(IHD),Oral Presentation (Japanese),
- 1 Long-Term Feasibility of TACT and Cardiac Regeneration Enhancement by Intra-Coronary Infusion of Peripheral Blood Mononuclear Cells (CARE-PB-AMI) or Erythropoietin (CARE-EPO-AMI)(Clinical Trials of Regeneration Therapy in Japan, The 71st Annual Scientif
- PE-621 Therapeutic Angiogenesis of Ischemic and Delta-Sarcoglycan Knockdown Myocardium by Adult Skeletal Muscle-derived Stem Cells(Regeneration (angionenesis/myocardial regeneration)-6 (M) PE110,Poster Session (English),The 70th Anniversary Annual Scienti