Prevalence of Right Bundle-Branch Block and Right Precordial ST-Segment Elevation (Brugada-Type Electrocardiogram) in Japanese Children

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Background The prevalence of Brugada-type electrocardiogram (ECG) in schoolchildren remains unclear. This study aimed to further investigate this condition. Methods and Results We studied the prevalence of Brugada-type ECG in 20,387 children (10,434 males and 9,953 females, 9.7±3.2 [SD] years old) during a school health examination in Kanagawa Prefecture, Japan, in 2002. We considered right bundle-branch block and ST-segment elevation of the J point of ≥ 0.1 mV in leads V_1 through V_3 as Brugada-like ECG, and an ECG was considered to be Brugada-type when the 12-lead ECG fully meet the criteria for the Brugada syndrome as recently published in a consensus report. Only 2 children (0.0098%, 95% confidence interval (CI) : 0 to 0.023%) completely conformed to the criteria for Brugada-type ECG. Brugada-like ECG was found in 11 (10 male) of 20,387 children (0.054%, 95% CI : 0.022 to 0.086%). The prevalence in males was significantly higher than that in females, even in children (0.096% vs 0.010%, p=0.012). Stratified according to age, there was tendency for the prevalence of Brugada-like ECG to increase up to puberty (first graders, 0.01% ; fourth graders, 0.05% ; seventh graders, 0.08% ; tenth graders, 0.23% ; p=0.068). Conclusion The prevalence of Brugada-type ECG in Japanese children was much lower than that reported in the adult population.
社団法人日本循環器学会の論文
2004-03-20