RELATIONSHIP BETWEEN BLOOD PRESSURE AND HEART RATE WHILE AWAKE AND ASLEEP IN PATIENTS WITH MILD ESSENTIAL HYPERTENSION
スポンサーリンク
概要
- 論文の詳細を見る
Blood pressure (BP) and heart rate (HR) (BP waveforms) are affected by external stress during waking and BP is reduced to its lowest level (base BP) during sleep. This study investigated the relationship between BP waveforms while awake and base BP waveforms during sleep. The intra-arterial BPs of 64 inpatients (34 males and 30 females, age: 42±11, mean±SD) with mild essential hypertension were measured for 24 h by the telemetry method. The average 1n (SBP/DBP) (m) while awake and the m at base BP (1n: natural logarithm, SBP' systolic BP, DBP: diastolic BP) had approximately the same values in each patient (mean difference: -0.02±0.07). The product of the RR interval (60/HR) and DBP (RR×DBP) while awake and at base BP had almost the same value (mean difference: -3.2±10 mmHg・sec). According to the Windkessel model, the RR interval during which blood-flow volume in relation to the m value is at its highest can be inferred as S (e^m-1)/(e^m-m-1) (S: systolic time). Using this formula, we developed a formula to estimate base RR from waking m. BP, and RR. Calculations with this estimate formula produced a very slight difference (0.0±0.1 sec) between estimated and actual values for base RR. For the most part, it was possible to infer the base DBP value from the estimated base RR using RR×DBP while awake (mean difference: -3.7±7.0 mmHg). These results suggest that the base BP waveform may be the most efficient pattern, and that waking BP waveforms change based on the base BP waveform during sleep.
- 社団法人日本循環器学会の論文
- 1993-11-20
著者
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Ishii Masao
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
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Kosuge Masami
Yokohama City University School Of Medicine Cardiovascular Center
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Matsushita Kohei
Second Department Of Internal Medicine Urafune Hospital Of Yokohama City University
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Tochikubo Osamu
Division Of Cardiology Yokohama City University Medical Center
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Imanishi Masahito
Department Of Internal Medicine
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Tochikubo Osamu
The Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Ishii M
Japan Medical Association
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Miyajima Eiji
Cardiovascular Division Yokohama City University School Of Medicine Medical Center
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TOCHIKUBO OSAMU
Second Department of Internal Medicine, Yokohama City University, School of Medicine
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MIYAJIMA EIJI
Second Department of Internal Medicine, Yokohama City University, School of Medicine
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ISHII Masao
Second Department of Internal Medicine, School of Medicine, Yokohama City University
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Kawano Yoshiyuki
Second Department of Internal Medicine, Urafune Hospital
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MINAMISAWA KHOSUKE
Second Department of Internal Medicine, Urafune Hospital of Yokohama City University
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Miyajima Eiji
Second Department Of Internal Medicine Yokohama City University School Of Medicine
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ISHII Masao
Research Group on Evaluation of the Effects of Drug Treatment on Hypertension and Other Disease Cond
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Tochikubo Osamu
Second Department Of Internal Medicine School Of Medicine Yokohama City University
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Ishii Masao
Second Department Of Internal Medicine School Of Medicine Yokohama City University
-
Miyajima Eiji
Division Of Cardiology Yokohama City University Medical Center
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Mitani Isao
Department Of Pediatric Cardiology Yokohama City University Hospital
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Ishii Masao
Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Miyajima Eiji
The Second Department Of Internal Medicine Yokohama City University Yokohama
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Minamisawa Khosuke
Second Department Of Internal Medicine Urafune Hospital Of Yokohama City University
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Ishii Masao
Second Department Of Internaal Medicine Yokohama City University
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Miyajima Eiji
Second Department Of Internal Medicine School Of Medicine Yokohama City University
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Kawano Yoshiyuki
Department Of Cardiology Cerebrovascular Center Nanasawa Rehabilitation Hospital
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Tochikubo Osamu
Second Department Of Internaal Medicine Yokohama City University
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Kawano Yoshiyuki
Second Department Of Internal Medicine Oita University
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