Nephrotic Syndrome Due to Primary AL Amyloidsis, Successfully Treated with VAD and Subsequent High-dose Melphalan Followed by Autologous Peripheral Blood Stem Cell Transplantation
スポンサーリンク
概要
- 論文の詳細を見る
Primary AL amyloidosis involves vital organs from the early phase of illness, resulting in a poor prognosis. We report a patient with nephrotic syndrome due to this type of amyloidosis, who was successfully treated with two courses of VAD (vincristine, doxorubicin and dexamethasone) and subsequent high-dose melphalan (140 mg/m2) with autologous stem cell support. Following the serial chemotherapy his proteinuria improved, and M protein became undetectable in both serum and urine. To avoid the progression of primary AL amyloidosis, intensive chemotherapy should be actively used when the general status and vital organ functions are well preserved.(Internal Medicine 42: 72-77, 2003)
- 社団法人 日本内科学会の論文
- 2003-01-01
著者
-
GONO Takahisa
Third Department of Medicine, Shinshu University School of Medicine
-
SAKASHITA Kazuo
Department of Pediatrics, Shinshu University School of Medicine
-
KOIKE Kenichi
Department of Pediatrics, Shinshu University School of Medicine
-
Koike Kenichi
The Department Of Pediatrics Shinshu University School Of Medicine
-
Tada Tsuyoshi
The Department Of Neurosurgery Shinshu University School Of Medicine
-
MATSUDA Masayuki
the Third Department of Medicine, Shinshu University School of Medicine
-
HOSHI Kenichi
Third Department of Medicine, Shinshu University School of Medicine
-
GONO Takahisa
the Third Department of Medicine, Shinshu University School of Medicine
-
HOSHI Kenichi
the Third Department of Medicine, Shinshu University School of Medicine
-
AIZAWA Masatsugu
the Department of Medicine, Fuji Hospital
-
Sakashita Kazuo
The Department Of Pediatrics Shinshu University School Of Medicine
-
Matsuda Masayuki
Third Department Of Medicine Shinshu University School Of Medicine
-
Dohi Naoko
The Third Department Of Medicine Shinshu University School Of Medicine
-
Ikeda Shu-ichi
The Third Department Of Internal Medicine Shinshu University School Of Medicine
-
Matsuda Masayuki
The Department Of Neurology Saku Central Hospital
-
Ikeda Shu-ichi
Department Of Neurology Shinshu University School Of Medicine
-
Aizawa Masatsugu
The Department Of Medicine Fuji Hospital
-
Matsuda Masayuki
The Third Department Of Medicine Shinshu University School Of Medicine
-
Ikeda Shu-ihci
Dep. Of Medicine (neurology And Rheumatology) Shinshu Univ. School Of Medicine
-
Matsuda Masayuki
Third Department Of Medicine (neurology And Rheumatology) Shinshu University School Of Medicine
-
Ikeda Shu-ichi
Third Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine
関連論文
- Serum Levels of Free Light Chain before and after Chemotherapy in Primary Systemic AL Amyloidosis
- Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy
- The safety of transcranial magnetic stimulation with deep brain stimulation instruments
- Association Between Serum Uric Acid Levels and Cardiometabolic Risk Factors Among Japanese Junior High School Students
- 小児悪性腫瘍患者由来α溶連菌における高頻度の meropenem 耐性
- Long-term Follow-up of Plasma Cells in Bone Marrow and Serum Free Light Chains in Primary Systemic AL Amyloidosis
- Successful Unrelated Cord Blood Transplantation Using a Reduced-Intensity Conditioning Regimen in a 6-Month-Old Infant with Congenital Neutropenia Complicated by Severe Pneumonia
- Specific Autoantibodies to Platelet Glycoproteins in Epstein-Barr Virus-Associated Immune Thrombocytopenia
- Conventional Diet Therapy for Hyperammonemia is Risky in the Treatment of Hepatic Encephalopathy Associated with Citrin Deficiency
- Metabolic derangements in deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier
- Risk of Worsened Encephalopathy after Intravenous Glycerol Therapy in Patients with Adult-onset Type II Citrullinemia (CTLN2)
- Hepatocellular Carcinoma in a Case of Adult-onset Type II Citrullinemia
- Myasthenia Gravis with Anti-MuSK Antibody, Showing Progressive Muscular Atrophy without Blepharoptosis
- Reactive Arthritis Due to Asymptomatic Infection of Chlamydia trachomatis
- Association Between Serum Uric Acid Levels and Cardiometabolic Risk Factors Among Japanese Junior High School Students
- Ten Years of Experience with Liver Transplantation for Familial Amyloid Polyneuropathy in Japan : Outcomes of Living Donor Liver Transplantations
- Recurrent Cerebral Embolism in a Familial Amyloid Polyneuropathy Patient Who Received Partial Liver Transplantation from a Living Donor
- Cytomegalovirus-induced Infectious Mononucleosis-like Syndrome in a Rheumatoid Arthritis Patient Treated with Methotrexate and Infliximab
- Successful Treatment with Rituximab in a Patient with Stiff-Person Syndrome Complicated by Dysthyroid Ophthalmopathy
- Takayasu's Arteritis in a Patient with Crohn's Disease: An Unexpected Association during Infliximab Therapy
- Therapeutic outcome of cyclic VAD (vincristine, doxorubicin and dexamethasone) therapy in primary systemic AL amyloidosis patients
- Successful treatment with infliximab and low-dose methotrexate in a Japanese patient with familial Mediterranean fever
- Increase in Incidence of Elderly-onset Patients with Myasthenia Gravis in Nagano Prefecture, Japan
- High-dose Melphalan Followed by Autologous Stem Cell Support in Primary Systemic AL Amyloidosis with Multiple Organ Involvement
- Serum Amyloid A as a Potent Therapeutic Marker in a Refractory Patient with Polymyalgia Rheumatica
- Retrospective Analyses of Clinical Features and Therapeutic Outcomes in Thymectomized Patients with Myasthenia Gravis at Shinshu University
- Intractable Skin Necrosis and Interstitial Pneumonia in Amyopathic Dermatomyositis, Successfully Treated with Cyclosporin A
- Hemolysis, Elevated Liver Enzymes and Low Platelet (HELLP) Syndrome Associated with Systemic Lupus Erythematosus
- Abdominal Fat Aspiration Biopsy and Genotyping of Serum Amyloid A Contribute to Early Diagnosis of Reactive AA Amyloidosis Secondary to Rheumatoid Arthritis
- Long-term Follow-up of Systemic Reactive AA Amyloidosis Secondary to Rheumatoid Arthritis: Successful Treatment with Intermediate-dose Corticosteroid
- Cytoplasmic Body Myopathy with Hypertrophic Cardiomyopathy
- Marked shrinkage of amyloid lymphadenopathy after an intensive chemotherapy in a patient with IgM-associated AL amyloidosis
- Rituximab therapy in nephrotic syndrome due to AH amyloidosis
- Hemophagocytic syndrome associated with rheumatoid arthritis: A case report and review of the literature
- Malignant Lymphoma Associated with Rheumatoid Arthritis, Developing Shortly after Initiation of Oral Methotrexate
- Senile Systemic Amyloidosis Starting as Bilateral Carpal and Left Ulnar Tunnel Syndrome
- Nephrotic Syndrome Due to Primary AL Amyloidsis, Successfully Treated with VAD and Subsequent High-dose Melphalan Followed by Autologous Peripheral Blood Stem Cell Transplantation
- Primary Cardiac Malignant Fibrous Histiocytoma in the Right Ventricular Infundibulum Treated With a Cavo-Pulmonary Shunt and Coronary Embolization
- An Unusual Case of Klippel-Trenaunay-Weber Syndrome Presenting with Portosystemic Encephalopathy
- A Novel RNA Splice Site Mutation in the C1 Inhibitor Gene of a Patient with Type I Hereditary Angioedema
- Recurrent Gastric Hemorrhaging with Large Submucosal Hematomas in a Patient with Primary AL Systemic Amyloidosis : Endoscopic and Histopathological Findings
- Unilateral Oculomotor Nerve Palsy Induced by Combination Therapy of Interferon-α2b and Ribavirin
- Diflunisal stabilizes familial amyloid polyneuropathy-associated transthyretin variant tetramers in serum against dissociation required for amyloidogenesis
- CLINICAL SIGNIFICANCE OF Tc-99m-PYP SCINTIGRAPHY IN THE DIAGNOSIS OF AMYLOID HEART DISEASE IN FAMILIAL AMYLOID POLYNEUROPATHY : Cardiomyopathy (II) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- M-MODE AND TWO-DIMENSIONAL ECHOCARDIOGRAPHIC FEATURES OF FAMILIAL AMYLOID POLYNEUROPATHY : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Cardiomyopathy
- Tacrolimus Related Brady and Tachyarrhythmias in a Familial Amyloid Polyneuropathy Patient who Underwent Partial Liver Transplantation
- Tacrolimus Related Brady and Tachyarrhythmias in a Familial Amyloid Polyneuropathy Patient who Underwent Partial Liver Transplantation
- Synergistic action of interleukin-10 (IL-10) with IL-3, IL-4 and stem cell factor on colony formation from murine mast cells in culture
- Frequent natural killer cell abnormality in children in an area highly contaminated by the Chernobyl accident
- Hypersomnia and Low CSF Hypocretin-1 (Orexin-A) Concentration in a Patient with Multiple Sclerosis Showing Bilateral Hypothalamic Lesions
- An 80-year-old Mitochondrial Disease Patient with A3243G tRNA^ Gene Presenting Cardiac Dysfunction as the Main Symptom
- Emotional Stress-Induced 'Ampulla Cardiomyopathy' : Discrepancy Between the Metabolic and Sympathetic Innervation Imaging Performed During the Recovery Course
- Characteristic Spinal MRI Findings of HIV-associated Myelopathy in an AIDS Patient
- Fasciitis in Mixed Connective Tissue Disease Successfully Treated with High-dose Intravenous Immunoglobulin
- Severe Depression as an Initial Symptom in an Elderly Patient with Acute Disseminated Encephalomyelitis.
- Myasthenia Gravis with Membranous Nephropathy, Successfully Treated with Extended Total Thymectomy
- A Primary Sjogren's Syndrome Patient with Marked Swelling of Multiple Exocrine Glands and Sclerosing Pancreatitis
- Paraneoplastic Neurologic Syndrome Associated with Small Breast Cancer : Diagnostic Value of FDG-PET for Detection of Underlying Malignancy
- Phenol Congo Red Staining Enhances the Diagnostic Value of Abdominal Fat Aspiration Biopsy in Reactive AA Amyloidosis Secondary to Rheumatoid Arthritis
- Skin Infiltration of Juvenile Myelomonocytic Leukemia
- Usefulness of [^I]metaiodobenzylguanidine ([^I]MIBG) Myocardial Scintigraphy in Differentiating between Alzheimer's Disease and Dementia with Lewy Bodies
- Nephrotic Syndrome Due to Primary AL Amyloidsis, Successfully Treated with VAD and Subsequent High-dose Melphalan Followed by Autologous Peripheral Blood Stem Cell Transplantation
- Enlargement of Multiple Cavernous Hemangioma of the Liver in Association with Pregnancy
- Fatal Acute Pancreatitis with Cystic Formation in Reactive Systemic AA Amyloidosis Secondary to Rheumatoid Arthritis
- Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus : case report and literature review
- Intractable Skin Necrosis and Interstitial Pneumonia in Amyopathic Dermatomyositis, Successfully Treated with Cyclosporin A
- Senile Systemic Amyloidosis Starting as Bilateral Carpal and Left Ulnar Tunnel Syndrome
- Migrating Osteoarthralgia: A Rare Initial Manifestation of Adult Leukemia