Association Between Serum Uric Acid Levels and Cardiometabolic Risk Factors Among Japanese Junior High School Students
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概要
- 論文の詳細を見る
Background: The present study was designed to examine whether serum uric acid (SUA) levels were associated with cardiometabolic risk factors and to determine optimal cut-offs for SUA to identify multiple risk factors among Japanese junior high school students. Methods and Results: A total of 958 students (518 boys and 440 girls, aged 12.1-15.0 years) who were enrolled between April 2005 and June 2008 were divided into 4 groups according to SUA quartiles. Compared with the lowest quartile of SUA, prevalence of abdominal obesity, hypertension, and dyslipidemia was significantly increased in the highest quartile in boys and that of abdominal obesity was increased in the highest quartile in girls. The adjusted odds ratios (95% confidence interval) of the highest quartile of SUA for 2 or more cardiometabolic risk factors were 2.59 (1.16-5.79) for boys and 1.54 (0.43-5.56) for girls. Receiver operating characteristic curve analysis demonstrated that the most appropriate cut-offs for SUA to identify multiple cardiometabolic risk factors were 6.4 mg/dl for boys and 4.9 mg/dl for girls. Conclusions: SUA was strongly associated with the prevalence of cardiometabolic risk factors among male Japanese junior high school students. The present study may provide insights into the role of SUA in the school screening system for the development of educational programs on prevention of lifestyle-related diseases among school children. (Circ J 2010; 74: 1570 - 1577)
- 2010-07-25
著者
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IKEDA Uichi
Department of Cardiovascular Medicine, Shinshu University Graduate School of Medicine
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KOIKE Kenichi
Department of Pediatrics, Shinshu University School of Medicine
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Yoshida Yukihiko
Division Of Cardiology Nagoya Dai-ni Red Cross Hospital Cardiovascular Center
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Hongo Minoru
Department of Cardiovascular Medicine, Shinshu University School of Health Sciences
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Hidaka Hiroya
Department of Clinical Laboratory Medicine, Shinshu University School of Health Sciences
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Sakaguchi Shigeko
Department of Nursing, Shinshu University School of Health Sciences
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Nakanishi Keisuke
Department of Nursing, Shinshu University School of Health Sciences
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Ichikawa Motoki
Department of Pediatrics, Shinshu University School of Health Sciences
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Hirota Naoko
Man Healthy Faculty of Matsumoto University
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Tanaka Naoki
Department of Gastroenterology, Shinshu University School of Medicine
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Tsuruta Goro
Department of Pediatrics, Shinshu University School of Medicine
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Yazaki Yoshikazu
Division of Cardiology, NHO Matsumoto Medical Center Matsumoto Hospital
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Kinoshita Osamu
Department of Cardiovascular Medicine, Azumino Red Cross Hospital
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Yoshida Yukihiko
Division Of Cardiology Nho Matsumoto Medical Center Matsumoto Hospital
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Kubo Keishi
Department Of Pediatrics Shinshu University School Of Medicine
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Hirabayashi Naoaki
Man Healthy Faculty Of Matsumoto University
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Takeda Naokazu
Department Of Gastroenterology Shinshu University School Of Medicine
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Hongo Minoru
Department Of Cardiovascular Medicine Shinshu University School Of Health Sciences
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Tsuruta Goro
Department Of Pediatrics Shinshu University School Of Medicine
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Koike Kenichi
Department Of Pediatrics Shinshu University School Of Medicine
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Hidaka Hiroya
Department Of Clinical Laboratory Medicine Shinshu University School Of Health Sciences
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Nakanishi Keisuke
Department Of Nursing Shinshu University School Of Health Sciences
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Ikeda U
Department Of Cardiovascular Medicine Shinshu University School Of Medicine
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Ikeda Uichi
Department Of Cardiology Jichi Medical School
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Tanaka Naoki
信州大学 保健学科循環器内科
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Kinoshita Osamu
Department Of Cardiovascular Medicine Azumino Red Cross Hospital
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Kinoshita Osamu
Department Of Cardiovascular Medicine And Regeneration Shinshu University Graduate School Of Medicin
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Ichikawa Motoki
Department Of Pediatrics Shinshu University School Of Health Sciences
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Yazaki Yoshikazu
Division Of Cardiology Nho Matsumoto Medical Center Matsumoto Hospital
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Sakaguchi Shigeko
Department Of Nursing Shinshu University School Of Health Sciences
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Ikeda Uichi
Dept. Of Cardiol. Jichi Med. Sch. Tochigi
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Yazaki Yoshikazu
Departments Of Cardiovascular Medicine Shinshu University School Of Medicine
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Yazaki Yoshikazu
The Division Of Cardiovascular Medicine Shinshu University School Of Medicine
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Kinoshita Osamu
The Division Of Cardiovascular Medicine Shinshu University School Of Medicine
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Ikeda Uichi
The Departments Of Cardiology Echi Medical School
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Ikeda Uichi
Departmrnt Of Cardiology Shinshu University
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Ikeda Uichi
The Department Of Cardiology Jichi Medical School
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Kinoshita Osamu
Department Of Cardiothoracic Surgery The University Of Tokyo
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Ikeda Uichi
Department Of Cardiology Shinshu University School Of Medicine
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Yazaki Yoshikazu
Division Of Cardiology National Matsumoto Medical Center Matsumoto Hospital
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Kinoshita Osarnu
The First Department Of Internal Medicine Shinshu University School Of Medicine
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Hongoh Minoru
Department Of Cardiovascular Medicine Shinshu University School Of Health Sciences
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Tanaka Naoki
Department Of Gastroenterology Shinshu University School Of Medicine
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Tanaka Naoki
Department Of Bio-molecular Engineering Kyoto Institute Of Technology
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Kinoshita Osamu
Department Of Cardiology Shinshu University School Of Medicine
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Ikeda Uichi
Division Of Cardiovascular Sciences Department Of Organ Regeneration Shinshu University Graduate School Of Medicine
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Nakanishi Keisuke
Department Of Materials Science And Engineering University Of Fukui
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Kinoshita Osamu
Department of Cardiac Surgery, Graduate School of Medicine, University of Tokyo
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