Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy
スポンサーリンク
概要
- 論文の詳細を見る
This is an electronic version of an article published in Amyloid 2010, Vol. 17, No. 1 : Pages 32-35. Amyloid is available online at: http://informahealthcare.com/doi/pdf/10.3109/13506121003619369We report here two patients with amyloidogenic transthyretin (ATTR) Val30Met familial amyloid polyneuropathy (FAP) who developed numbness in both hands and were diagnosed as having bilateral carpal tunnel syndrome (CTS). In both patients systemic TTR amyloidosis consisting of polyneuropathy affecting both upper and lower limbs and/or autonomic dysfunction gradually appeared after surgery for CTS. Although CTS associated with TTR amyloidosis has been known as an initial symptom in some patients with ATTR non-Val30Met FAP and those with senile systemic amyloidosis, this is the first report of ATTR Val30Met FAP patients starting with upper limb neuropathy including CTS-like symptoms. It is also notable that both patients had no genealogical relationship with two Japanese endemic foci of this disease.
著者
-
Ikeda Shuichi
The Third Department Of Medicine Shinshu University School Of Medicine
-
Ikeda Shu-ichi
Department Of Neurology Shinshu University School Of Medicine
-
Sekijima Yoshiki
The Third Department Of Medicine Shinshu University School Of Medicine
-
Shimojima Yoshio
Third Department Of Medicine Shinshu University School Of Medicine
-
Shimojima Yasuhiro
Third Department Of Medicine (neurology And Rheumatology) Shinshu University School Of Medicine
-
Ikeda Shu-ichi
Third Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine
関連論文
- Serum Levels of Free Light Chain before and after Chemotherapy in Primary Systemic AL Amyloidosis
- Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy
- The safety of transcranial magnetic stimulation with deep brain stimulation instruments
- Myasthenia Gravis with Anti-MuSK Antibody, Showing Progressive Muscular Atrophy without Blepharoptosis
- Reactive Arthritis Due to Asymptomatic Infection of Chlamydia trachomatis
- Cytomegalovirus-induced Infectious Mononucleosis-like Syndrome in a Rheumatoid Arthritis Patient Treated with Methotrexate and Infliximab
- Successful Treatment with Rituximab in a Patient with Stiff-Person Syndrome Complicated by Dysthyroid Ophthalmopathy
- Takayasu's Arteritis in a Patient with Crohn's Disease: An Unexpected Association during Infliximab Therapy
- Therapeutic outcome of cyclic VAD (vincristine, doxorubicin and dexamethasone) therapy in primary systemic AL amyloidosis patients
- Successful treatment with infliximab and low-dose methotrexate in a Japanese patient with familial Mediterranean fever
- Increase in Incidence of Elderly-onset Patients with Myasthenia Gravis in Nagano Prefecture, Japan
- High-dose Melphalan Followed by Autologous Stem Cell Support in Primary Systemic AL Amyloidosis with Multiple Organ Involvement
- Serum Amyloid A as a Potent Therapeutic Marker in a Refractory Patient with Polymyalgia Rheumatica
- Retrospective Analyses of Clinical Features and Therapeutic Outcomes in Thymectomized Patients with Myasthenia Gravis at Shinshu University
- Intractable Skin Necrosis and Interstitial Pneumonia in Amyopathic Dermatomyositis, Successfully Treated with Cyclosporin A
- Hemolysis, Elevated Liver Enzymes and Low Platelet (HELLP) Syndrome Associated with Systemic Lupus Erythematosus
- Abdominal Fat Aspiration Biopsy and Genotyping of Serum Amyloid A Contribute to Early Diagnosis of Reactive AA Amyloidosis Secondary to Rheumatoid Arthritis
- Long-term Follow-up of Systemic Reactive AA Amyloidosis Secondary to Rheumatoid Arthritis: Successful Treatment with Intermediate-dose Corticosteroid
- Cytoplasmic Body Myopathy with Hypertrophic Cardiomyopathy
- Marked shrinkage of amyloid lymphadenopathy after an intensive chemotherapy in a patient with IgM-associated AL amyloidosis
- Rituximab therapy in nephrotic syndrome due to AH amyloidosis
- Hemophagocytic syndrome associated with rheumatoid arthritis: A case report and review of the literature
- Malignant Lymphoma Associated with Rheumatoid Arthritis, Developing Shortly after Initiation of Oral Methotrexate
- Senile Systemic Amyloidosis Starting as Bilateral Carpal and Left Ulnar Tunnel Syndrome
- An Unusual Case of Klippel-Trenaunay-Weber Syndrome Presenting with Portosystemic Encephalopathy
- A Novel RNA Splice Site Mutation in the C1 Inhibitor Gene of a Patient with Type I Hereditary Angioedema
- Unilateral Oculomotor Nerve Palsy Induced by Combination Therapy of Interferon-α2b and Ribavirin
- Diflunisal stabilizes familial amyloid polyneuropathy-associated transthyretin variant tetramers in serum against dissociation required for amyloidogenesis
- Characteristic Spinal MRI Findings of HIV-associated Myelopathy in an AIDS Patient
- Fasciitis in Mixed Connective Tissue Disease Successfully Treated with High-dose Intravenous Immunoglobulin
- Severe Depression as an Initial Symptom in an Elderly Patient with Acute Disseminated Encephalomyelitis.
- Paraneoplastic Neurologic Syndrome Associated with Small Breast Cancer : Diagnostic Value of FDG-PET for Detection of Underlying Malignancy
- Phenol Congo Red Staining Enhances the Diagnostic Value of Abdominal Fat Aspiration Biopsy in Reactive AA Amyloidosis Secondary to Rheumatoid Arthritis
- Nephrotic Syndrome Due to Primary AL Amyloidsis, Successfully Treated with VAD and Subsequent High-dose Melphalan Followed by Autologous Peripheral Blood Stem Cell Transplantation
- Fatal Acute Pancreatitis with Cystic Formation in Reactive Systemic AA Amyloidosis Secondary to Rheumatoid Arthritis
- Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus : case report and literature review