High-dose Melphalan Followed by Autologous Stem Cell Support in Primary Systemic AL Amyloidosis with Multiple Organ Involvement
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概要
- 論文の詳細を見る
A patient with primary systemic AL amyloidosis achieved partial hematological response after 2 courses of VAD (vincristine, doxorubicin and dexamethasone) and subsequent high-dose melphalan followed by autologous peripheral blood stem cell transplantation despite involvement of multiple organs, including the heart. In this patient natriuretic peptides and free light chains in serum were useful as markers of cardiac involvement and therapeutic effects, respectively. When amyloidosis-related dysfunction is seen in multiple organs, this intensive chemotherapy might be a possible therapeutic option, although several modifications in the regimen and careful management are necessary.
- 社団法人 日本内科学会の論文
- 2005-05-01
著者
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MATSUDA Masayuki
Third Department of Medicine, Shinshu University School of Medicine
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SHIMOJIMA Yasuhiro
Third Department of Medicine, Shinshu University School of Medicine
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ISHII Wataru
Third Department of Medicine, Shinshu University School of Medicine
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SAKASHITA Kazuo
Department of Pediatrics, Shinshu University School of Medicine
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KOIKE Kenichi
Department of Pediatrics, Shinshu University School of Medicine
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IKEDA Shu-ichi
Third Department of Medicine, Shinshu University School of Medicine
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SHIMODAIRA Shigetaka
Department of Internal Medicine, Japanese Red Cross Nagano Hospital
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Koike Kenichi
Department Of Pediatrics Shinshu University School Of Medicine
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Koike Kenichi
The Department Of Pediatrics Shinshu University School Of Medicine
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KOYAMA Jun
Third Department of Medicine, Shinshu University School of Medicine
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YAMAMOTO Kanji
Third Department of Medicine, Shinshu University School of Medicine
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Sakashita Kazuo
Department Of Pediatrics Shinshu University School Of Medicine
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Sakashita Kazuo
The Department Of Pediatrics Shinshu University School Of Medicine
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Ikeda Shuichi
The Third Department Of Medicine Shinshu University School Of Medicine
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Matsuda Masayuki
Third Department Of Medicine Shinshu University School Of Medicine
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Koyama Jun
Third Department Of Medicine Shinshu University School Of Medicine
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Yamamoto Kanji
Third Department Of Medicine Shinshu University School Of Medicine
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Ikeda Shu-ichi
Third Department Of Medicine Shinshu University School Of Medicine
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Matsuda Masayuki
The Department Of Neurology Saku Central Hospital
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Shimodaira Shigetaka
Department Of Blood Transfusion Shinshu University School Of Medicine
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Ikeda Shu-ichi
Department Of Neurology Shinshu University School Of Medicine
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Ishii Wataru
The Third Department Of Medicine Shinshu University School Of Medicine
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Yamamoto Kanji
The Department Of Neurology Toyoshina Red-cross Hospital
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Sekijima Yoshiki
The Third Department Of Medicine Shinshu University School Of Medicine
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Shimojima Yoshio
Third Department Of Medicine Shinshu University School Of Medicine
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Matsuda Masayuki
The Third Department Of Medicine Shinshu University School Of Medicine
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Ikeda Shu-ihci
Dep. Of Medicine (neurology And Rheumatology) Shinshu Univ. School Of Medicine
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Shimojima Yasuhiro
Third Department Of Medicine (neurology And Rheumatology) Shinshu University School Of Medicine
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Ikeda Shu-ichi
Third Department Of Medicine (neurology And Rheumatology) Shinshu University School Of Medicine
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Matsuda Masayuki
Third Department Of Medicine (neurology And Rheumatology) Shinshu University School Of Medicine
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Ishii Wataru
Third Department Of Medicine (neurology And Rheumatology) Shinshu University School Of Medicine
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Ikeda Shu-ichi
Third Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine
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