Pathogenetic Role of Vascular Angiotensin Converting Enzyme (ACE) in SHR
スポンサーリンク
概要
著者
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Okunishi Hideki
Department Of Pharmacology Shiga University Of Medical Sciences
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Miyazaki Mizuo
Department Of Pharmacoldgy Osaka Medical College
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Kawamoto Tatsuhiko
Department of Pharmacology, Osaka Medical College
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Nakamura Masuhisa
Shionogi Research Laboratories
関連論文
- New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Chymase as an Important Target to Prevent Organ Damage
- Long-Term Angiotensin II Blockade May Improve Not Only Hyperglycemia but Also Age-Associated Cardiac Fibrosis
- OE-235 Evidence of Plaque Neovascularization and Effects of Angiotensin Receptor Blocker in Cholesterol-Fed Monkey(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-307 Imidapril Attenuates MMP-9 Level More Effectively than Losartan in Patients with Acute Myocardial Infarction Treated by Primary-Percutaneous Coronary Intervention(Acute myocardial infarction, clinical(diagnosis/treatment)(02)(IHD),Oral Presentation
- PE-317 Angiotensin Receptor 1 Blocker Inhibits Atherosclerotic Changes of Aortic Valve by Preserving Endothelial Cells and Inhibiting Transformation into Osteoblast Phenotype(Vascular heart disease/Pericarditis/Cardiac tumor-2 (M) PE53,Poster Session (Eng
- Evidence for Abundant Presence of Chymase-Positive Mast Cells in the Kidneys of Patients with Immunoglobulin A Nephropathy : Effect of Combination Therapy with Prednisolone and Angiotensin II Receptor Blocker Valsartan
- Inhibition of Human Chymase by Suramin
- Angiotensin II Type 1 Receptor Antagonist, TCV-1 16, Prevents Neointima Formation in Injured Arteries in the Dog
- IS005 Vascular Smooth Muscle Cell(VSMC)-Specific Overexpression of Angiotensin type2(AT2)Receptor Causes Endothelium-dependent Vasodilation via bradykinin/NO/cGMP pathway
- Inhibition of the Angiotensin II Type 1 Receptor by TCV-116: Quantitation by In Vitro Autoradiography
- P218 INTERACTION OF VASCULAR SMOOTH MUSCLE CELLS(VSMC) WITH EXTRACELLULAR MATRIX(ECM) : EFFECTS OF THE PURIFIED HUMAN CHYMASE ON VSMC ATTACHMENT TO ECM
- Chymase inhibition attenuates tetrachloride-induced liver fibrosis in hamsters
- Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet
- Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats
- Anti-Atherosclerotic Effects of Dihomo-γ-Linolenic Acid in ApoE-Deficient Mice
- Chymase Inhibition Provides Pancreatic Islet Protection in Hamsters With Streptozotocin-Induced Diabetes
- Involvement of Vascular Angiotensin II-Forming Enzymes in the Progression of Aortic Abdominal Aneurysms in Angiotensin II-Infused ApoE-Deficient Mice
- Significance of chymase-dependent angiotensin II formation in the progression of human liver fibrosis
- Characterization of Recombinant Human Chymase Expressed in Escherichia coli
- -96-HYPOTENSIVE EFFECT OF A SPECIFIC INHIVITOR OF HUMAN RENIN
- OJ-062 Effect of Chymase Inhibition by NK-3201 on Hypoxia-Induced Left Ventricular Remodeling in Mice(Cardiovascular pharmacology, basic/clinical(02)(H),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- The Significance of Chymase in the Progression of Abdominal Aortic Aneurysms in Dogs
- OJ-199 Role of Chymase and MMPs in Angiotensin II-induced Abdominal Aortic Aneurysms(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- The Effects of Chymase on Matrix Metalloproteinase-2 Activation in Neointimal Hyperplasia after Balloon Injury in Dogs
- Tissue Angiotensin II Generating System by Angiotensin-Converting Enzyme and Chymase
- PJ-418 Effects of Chymase Inhibition on the Stenosis after Polytetrafluoroethylene Grafts Implantation(Restenosis, basic/clinical-5 (IHD) PJ71,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PE-278 Chymase Inhibition Prevents the Progression of Abdominal Aortic Aneurysm in Dogs(Peripheral circulation-5 (H) PE47,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Chymase Inhibition Prevents Cardiac Fibrosis and Dysfunction after Myocardial Infarction in Rats
- Role of Chymase-Dependent Angiotensin II Formation in Regulating Blood Pressure in Spontaneously Hypertensive Rats
- The Effect of Chymase Inhibition on Arteriovenous Fistula Stenosis in Dogs (Peripheral Circulation/Vascular Disease 6 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- A Potent Chymase Inhibitor, Suc-Val-Pro-Phe(p)(OPh)(2), Suppresses the Development of Abdominal Aortic Aneurysm in Dogs(Valvular Heart Disease/Pericarditis/Cardiac Tumor 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Effect of Chymase-Dependent Transforming Growth Factor β on Peritoneal Adhesion Formation in a Rat Model
- A Single Treatment With a Specific Chymase Inhibitor, TY-51184, Prevents Vascular Proliferation in Canine Grafted Veins
- PJ-043 An Antiarrhythmic Effect of A Chymase Inhibitor After Myocardial Infarction(Acute Myocardial Infarction, Basic 2 (IHD) : PJ8)(Poster Session (Japanese))
- Impact of Chymase Inhibitor on Cardiac Function and Survival after Myocardial Infarction
- Oral Administration of a Specific Chymase Inhibitor, NK3201, Suppresses the Development of Aneurysmal Dilatation on Hamster Experimental Aneurysm Model
- Possible Roles of Angiotensin II-Forming Enzymes, Angiotensin Converting Enzyme and Chymase-like Enzyme, in the Human Aneurysmal Aorta
- Effect of Chymase Inhibitor on Vascular Proliferation
- Development of the Chymase Inhibitor as an Anti-Tissue-Remodeling Drug : Myocardial Infarction and Some Other Possibilities
- Therapeutic Potential of a Specific Chymase Inhibitor in Atopic Dermatitis
- Recombinant Human Chymase Produced by Silkworm-Baculovirus Expression System : Its Application for a Chymase Detection Kit
- Oral Administration of a Novel Chymase Inhibitor, NK3201, Prevents Peritoneal Adhesion Formation in Hamsters
- Mast Cells as a Target of Rheumatoid Arthritis Treatment
- Inhibition of chymase improves cardiac function via suppression of fibrosis in hamster cardiomyopathic model
- Role of chymase in the development of aneurysmal formation; An experimental aneurysm model
- Beneficial Effects of Angiotensin-Converting Enzyme Inhibition in Adriamycin-Induced Cardiomyopathy in Hamsters
- Possible Roles of Cardiac Chymase After Myocardial Infarction in Hamster Hearts
- Local Angiotensin II-Generating System in Vascular Tissues: the Roles of Chymase
- An Orally Active Chymase Inhibitor, BCEAB, Suppresses Heart Chymase Activity in the Hamster
- The Functional Ratio of Chymase and Angiotensin Converting Enzyme in Angiotensin I-Induced Vascular Contraction in Monkeys, Dogs and Rats
- OE-273 Involvement of Superoxide in Angiotensin II-induced Hypertension is Unmasked by Development of Nox1-deficient Mice(Hypertension, basic-1 (H) OE46,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
- Trans-Differentiation of Bone Marrow Monocyte-Lineage Cells to Endothelial-Like Cells and Reendothelialization on Injured Endothelium by MCP-1-Dependent Adhesion
- Characteristics of Monkey Tryptase Purified From Cheek Pouch Vascular Tissues
- PE-398 Nuclear Factor-κ B Activation Accelerates Cardiac Hypertrophy, Interstitial Fibrosis, and Oxidative Stress in Diabetic Rats Exposed to Intermittent Hypoxia(Chronic coronary heart disease/Remodeling-2, The 71st Annual Scientific Meeting of the Japan
- Pulmonary Edema Induced by Angiotensin II in Rats
- EFFECT OF INTRA-AORTIC BALLOON PUMPING AND CALCIUM ANTAGONIST FOR REDUCING CORONARY REPERFUSION INJURY
- Failure of peripheral blood lymphocytes to be a surrogate marker of arterial tissue for tissue ace inhibition
- A technical note for the squeezed-flow perfusion method: sensitive monitoring of vasomotion of medium-sized, isolated blood vessels
- Effective inhibition of tissue angiotensin-converting enzyme attenuates pressure-overload aortic hypertrophy in early stage in rats
- 21B-11-5 Cyclohexanediols, the metabolites of ester side-chain of candesartan cilexetil (TCV-116), provoke digoxin arrhythmia in heart failure dogs.
- Differential Suppression of Pressure-Overload Cardiac and Aortic Hypertrophy in Rats by Angiotensin-Converting Enzyme Inhibitors
- G-CSF Treatment Inhibits Neointimal Hyperplasia Associated with Endothelial Progenitor Cell Mobilization and Acceleration of Reendothelialization in Catorid Artery Injuty Model(Restenosis after Angioplasty, Basic/Clinical 5 (IHD), The 69th Annual Scientif
- Critical Role of Tyrosine Kinase PYK2 in eNOS Activation Revealed by Analysis of PYK2 Knockout Mice(Endothelium/NO 5 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-417 Tyrosine Kinase PYK2 activates eNOS and subsequently regulates Vascular Tonus and Angiogenesis, revealed by its Knock-out Mice(Endothelium/NO 5 (H) : OJ51)(Oral Presentation (Japanese))
- eNOS Activation and Its Vascular Functions Critically Requires the Presence of Tyrosine Kinase PYK2
- OJ-028 G-CSF Treatment Inhibits Neointimal Formation after Arterial Injury through the Mobilization of Endothelial Progenitor Cell and Acceleration of Reendothelialization(Restenosis, basic/clinical-1 (IHD) OJ5,Oral Presentation (Japanese),The 70th Annive
- Inhibition of Vascular Angiotensin-Converting Enzyme by Telmisartan via the Peroxisome Proliferator-Activated Receptor γ Agonistic Property in Rats
- Inhibition of Matrix Metalloproteinase-9 Activity by Trandolapril after Middle Cerebral Artery Occlusion in Rats
- PROTECTION OF CORONARY REPERFUSION INJURY BY A CALCIUM ANTAGONIST
- ADRENOCEPTOR SUBTYPES IN FROG AORTA
- LENGTH-PASSIVE TENSION RELATIONSHIPS IN CEREBRAL AND PERIPHERAL ARTERIES ISOLATED FROM SPONTANEOUSLY HYPERTENSIVE AND NORMOTENSIVE RATS
- Effects of Elcatonin on Plasma and Urine Electrolytes in Infant Beagles
- Inhibition of Dog Renin Activity by Pepstatin A : VIII CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- A disynaptic pathway from the central amygdaloid nucleus to the paraventricular hypothalamic nucleus via the parastrial nucleus in the rat
- Trandolapril Reduces Infarction Area after Middle Cerebral Artery Occlusion in Rats
- Effects of a Lipoxygenase Inhibitor, Panaxynol, on Vascular Contraction Induced by Angiotensin II
- Significance of Angiotensin II Receptor Blocker Lipophilicities and Their Protective Effect against Vascular Remodeling
- Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats
- EFFECTS OF ELCATONIN ON PLASMA AND URINE ELECTROLYTES IN INFANT BEAGLES
- Comparative Effects of Candesartan and Amlodipine in a Monkey Atherosclerotic Model
- Significant Target Organs for Hypertension and Cardiac Hypertrophy by Angiotensin-Converting Enzyme Inhibitors
- Significance of Vascular Angiotensin-Converting Enzyme in the Depressor Mechanism by Angiotensin-Converting Enzyme Inhibitors
- Comparative Study on Salivary Distribution of Fluoroquinolones in Rats
- Pharmacological Profiles of a Novel Non-peptide Angiotensin II Type I Receptor Antagonist HR720 In Vitro and In Vivo
- EFFECTS OF GLUCAGON ON THE RENAL HEMODYNAMICS IN THE DOG
- RENIN INHIBITORY EFFECT OF N-ACETYL-PEPSTATIN
- REGIONAL AND SPECIES DIFFERENCES IN THE RESPONSE OF ISOLATED ARTERIES TO ANGIOTENSIN II
- Purification of L-Glutamate Decarboxylase from Monkey Brain
- EFFECTS OF RENAL VENOUS PRESSURE ELEVATION ON RENAL HEMODYNAMICS, URINE FORMATION AND RENIN RELEASE
- CONTROL OF RENIN SECRETION IN THE ANESTHETIZED DOG (3) EFFECTS OF HYPERTONIC MANNITOL INFUSION
- Control of Renin Secretion in the Anesthetized Dog 2) Relationship between Renin Secretion, Plasma Sodium Concentration and GFR in the Perfused Kidney
- Preface
- CONTRACTILE RESPONSES OF ISOLATED DOG MESENTERIC ARTERIES TO ANGIOTENSIN I, II AND III
- Purification of L-Glutamate Decarboxylase from Monkey Brain
- Changes in the ratio of urinary α1-microglobulin to ulinastatin levels in patients with Alzheimer-type dementia and vascular dementia
- A technical note for the squeezed-flow perfusion method : sensitive monitoring of vasomotion of medium-sized, isolated blood vessels
- In Vitro Pharmacology of a Novel Non-Peptide Angiotensin II-Receptor Antagonist, E4177
- Marked Species-Difference in the Vascular Angiotensin II-Forming Pathways: Humans versus Rodents.
- Hypotensive effect of SA446, an angiotensin converting enzyme inhibitor, in 2-kidney, 1-clip renal hypertensive and normotensive dogs.
- Pathogenetic Role of Vascular Angiotensin Converting Enzyme (ACE) in SHR