Real Time Analog Computation of Left Ventricular Systolic Pressure Volume Area as Predictor of Oxygen Consumption
スポンサーリンク
概要
- 論文の詳細を見る
An analog circuit was devised for real time determination of the left ventricular systolic pressure volume area (PVA), which we had recently identified as a reliable predictor of cardiac oxygen consumption rate per beat. PVA is the specific area in the pressure-volume diagram that is bounded by the end-systolic and end-diastolic pressure-volume relationship lines and the systolic segment of the pressure-volume loop trajectory of the left ventricle. The computed PVA was compared with PVA obtained as usual by planimetry. Correlation coefficient between the two PVAs was 0.997 (N=31, p<0.001) and the standard error of mean of the difference between the two PVAs was as small as practically negligi-ble 8mmHg ml in the PVA range from 0 to 2, 000mmHg ml. We concluded that this PVA analog computer can be used for real time determination of PVA, expediting the future studies of the relationship between PVA and cardiac oxygen consumption
- International Heart Journal刊行会の論文
著者
-
Suga Hiroyuki
Department Of Cardiovascular Dynamics National Cardiovascular Center Research Institute
-
MATSUSHITA Gota
Department of Cardiac Physiology, National Cardiovascular Center Research Institute
-
SUGA Hiroyuki
Department of Cardiac Physiology, National Cardiovascular Center Research Institute
関連論文
- A New Approach to Imidazo[1,2-a]pyridine Derivatives and Their Application to the Syntheses of Novel 2H-Pyrano[2’,3’:4,5]imidazo[1,2-a]pyridin-2-one Derivatives
- Synthesis of Spiro[2-cyclopentene-1,3’-imidazo[1,2-a]pyridine] Derivatives and Their Interesting Behavior in 1H-NMR Spectra in Deuteriochloroform
- Preparation of New Nitrogen-Bridged Heterocycles 67. Syntheses of α,α′-Bis[(thieno[3,4-b]indolizin-3-yl)thio]-o-, m-, and p-xylene Derivatives and Their Conformational Structures
- Preparation of New Nitrogen-Bridged Heterocycles. 60. Syntheses and Conformational Analyses of Bis(indolizin-1-yl) Disulfides
- Preparation of New Nitrogen-Bridged Heterocycles. 59. Syntheses and Intramolecular Interactions of 3-(Acylmethylthio)- and 3-[(3-Ethoxycarbonyl-2-propenyl)thio] thieno [3,4-b] indolizine Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 55. Reinvestigation of the Bromination/Dehydrobromination of Ethyl 3-[2-(Methylthio)indolizin-3-yl] acrylate Derivatives
- Mode of frequency distribution of external work efficiency of arrhythmic beats during atrial fibrillation remains normal in canine heart
- High Mechanical Efficiency of Left Ventricular Arrhythmic Contractions during Atrial Fibrillation
- Variable Unstressed Volume Keeps Normal Distributions of Canine Left Ventricular Contractility and Total Mechanical Energy under Atrial Fibrillation
- Predictability of O_2 Consumption from Contractility and Mechanical Energy of Absolute Arrhythmic Beats in Canine Heart
- Exponential Fitting of Postextrasystolic Potentiation May Underestimate the Cardiac Ca^ Recirculation Fraction : A Theoretical Analysis
- Myocardial protective effects of University of Wisconsin Solution (UWS), Celsior, and St.Thomas' Hospital Solution (STH) on postischemic donor heart performance
- Cardiovascular Beneficial Effects of Electroacupuncture at Neiguan (PC-6) Acupoint in Anesthetized Open-Chest Dog
- New Index for Oxygen Cost of Contractility from Curved End-Systolic Pressure-Volume Relations in Cross-Circulated Rat Hearts
- Hybrid Logistic Characterization of Isometric Twitch Force Curve of Isolated Ferret Right Ventricular Papillary Muscle
- Effects of Myosin Isozyme Shift on Curvilinearity of the Left Ventricular End-Systolic Pressure-Volume Relation of In Situ Rat Hearts
- Pressure-Interval Relationship Characterizes Left Ventricular Irregular Beat Contractilities and Their Mean Level during Atrial Fibrillation
- Sinusoidal and Exponential Decays of Postextrasystolic Transient Alternans in Excised Blood-Perfused Canine Hearts
- Postextrasystolic Contractility Normally Decays in Alternans in Canine In Situ Heart
- Validity of transeient Ees compared with stable Ees
- Frequency Distribution, Variance, and Moving Average of Left Ventricular Rhythm and Contractility during Atrial Fibrillation in Dog
- Frank-Starling Mechanism Retains Recirculation Fraction of Myocardial Ca^ in the Beating Heart
- Effective Arterial Elastance of Irregular Beats during Atrial Fibrillation in Canine Left Ventricle
- Preparation of New Nitrogen-Bridged Heterocycles 72. A New Approach to 1-Acyl-3-(substituted methylthio)thieno[3′,4′:4,5]imidazo[1,5-a]pyridine Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 56. Syntheses and Reactions of 1-[2,2-Bis(alkylthio)-1-(ethoxycarbonylacetyl)vinyl]pyridinium Salts
- Enantio-and Diastereoselectivity in 1,3-Dipolar Cycloaddition Reactions of Nitrones with 3-Crotonoyl-2-oxazolidinone Catalyzed by Ni(II)-Binaphthyldiimine Complexes
- Asymmetric Cyclopropanation and Aziridination Reactions of Olefins Catalyzed by Cu(I)-Binaphthyldiimine Complexes
- Preparation of New Nitrogen-Bridged Heterocycles.51.^ Syntheses and Structures of Compounds Having Two Indolizine Nuclei in a Molecule
- Stereocontrol in a Ytterbium Triflate-Catalyzed 1,3-Dipolar Cycloaddition Reaction of Carbonyl Ylide with N-substituted Maleimides and Dimethyl Fumarate
- Preparation of New Nitrogen-Bridged Heterocycles. 46. Selective Formation of 4(1H)-8,8a-Dihydro-1,4-thiazino[3,4,5-cd]indolizinone and (E)-3-(1,3-Oxathiol-2-ylidene)-2(3H)-indolizinone Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 45. Smooth Hydrolysis of 6-Membered Heterocyclic 2-Imines with Partial Aromaticity
- Ryanodine Decreases Internal Ca^ Recirculation Fraction of the Canine Heart as Studied by Postextrasystolic Transient Alternans
- 2, 3-Butanedione Monoxime Suppresses Excitation-Contraction Coupling in the Canine Blood-Perfused Left Ventricle
- Preparation of New Nitrogen-Bridged Heterocycles. 68. One-Pot Synthesis of 4-Substituted 5-Acylthieno[3,2-d]thiazole Derivatives
- Synthesis of 2, 5-Dihydro-1, 2, 4-oxadiazoles through Formal [3+2] Cycloaddition of Oxazoles with Nitrosobenzene Derivatives
- Regio-Control of Formal [3 + 2] Cycloadditions of 5-Alkoxyoxazoles with Diethyl Oxomalonate
- Chiral 2, 2′-Binaphthyldiimine-Nickel(II) Complexes as Lewis Acid Catalysts for Enantioselective Diels-Alder Reactions
- Asymmetric Diels-Alder Reactions Catalyzed by Chiral Ni(II)-Binaphthyldiimine Complexes
- CANINE RIGHT VENTRICULAR MECHANICAL WORK AND OXYGEN CONSUMPTION : APPLICATION OF PVA TO THE RIGHT VENTRICLE : Cardiac Function (III) : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- Preparation of New Nitrogen-Bridged Heterocycles. 58. : Syntheses and Intramolecular Arene-π Interactions of 3-(Allylthio)- and 3-(Propargylthio)thieno[3,4-b]indolizine Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 54. Increased Arene-Arene Interactions of 3-(Bicyclic and Tricyclic Arylmethylthio)thieno[3,4-b]indolizine Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 53. Syntheses of 3-(Benzylthio)thieno[3,4-b]indolizine Derivatives and Their Intramolecular Arene-Arene Interactions
- Linear O_2 Use-Pressure-Volume Area Relation from Curved End-Systolic Pressure-Volume Relation of the Blood-Perfused Rat Left Ventricle
- DENOPAMINE (BETA_1-SELECTIVE ADRENERGIC RECEPTOR AGONIST) AND ISOPROTERENOL (NON-SELECTIVE BETA-ADRENERGIC RECEPTOR AGONIST) EQUALLY INCREASE HEART RATE AND MYOCARDIAL OXYGEN CONSUMPTION IN DOG HEART
- -0217-O_2 CONSUMPTION DURING VENTRICULAR FIBRILLATION IN COOLING CAN BE ACCOUNTED FOR BY EQUIVALENT PRESSURE-VOLUME AREA
- -0209-DECREASED CONTRACTILITY AND INCREASED ENERGETIC COST OF CONTRACTILITY IN STUNNED MYOCARDIUM
- -0204-THE EFFECTS OF DYNAMIC CARDIAC COMPRESSION ON VENTRICULAR ENERGETICS
- -372-EFFECTS OF BLOOD-BORN CATECHOLAMINES ON LEFT VENTRICULAR Emax AND OXYGEN CONSUMPTION IN THE EXCISED CROSSCIRCULATED DOG HEART : Ventricular Function : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULA
- -126-DOSE A CALCIUM SENSITIZER, DPI 201-106, IMPROVE MYOCARDIAL EFFICIENCY IN DOG LEFT VENTRICLE? : COMPARISON TO EPINEPHRINE : Cardiovascular Drugs : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION S
- Relationship between parameters of the urea kinetic model and serum amino acid levels in patients on hemodialysis
- Hybrid Logistic Characterization of Isometric Twitch Force-Time Curve of Intact Blood-Perfused Canine Right Ventricular Papillary Muscle
- Effects of Ca^ and Epinephrine on Ca^ Recirculation Fraction and Total Ca^ Handling in Canine Left Ventricles
- Effects of Intracoronary Caffeine on Left Ventricular Mechanoenergetics in Ca^ Overload Failing Rat Hearts
- Left Ventricular Mechanoenergetics under Altered Coronary Perfusion in Guinea Pig Hearts
- NORMALIZATION OF END-SYSTOLIC PRESSURE-VOLUME RELATION AND Emax OF DIFFERENT SIZED HEARTS
- Digital On-Line Computation of a Predictor of Cardiac Oxygen Consumption : Left Ventricular Systolic Pressure Volume Area
- Hemodynamics of Experimentally Hypertensive Rats in Conscious and Anesthetized States
- Real Time Analog Computation of Left Ventricular Systolic Pressure Volume Area as Predictor of Oxygen Consumption
- Factors Delaying End Ejection from End Systole of Ventricle
- Correlative Changes in Total Vascular Capacity and Resistance in Carotid Sinus Reflex
- Effect of Increasing Age on Hemodynamics of Spontaneously Hypertensive Rats
- Hemodynarnics of Spontaneously Hypertensive Rats in Conscious State
- -150-MECHANISMS OF HYPERKINESIS IN NONISCHEMIC REGION OF ACUTE ISCHEMIC CANINE HEART
- -139-ASSESSMENT OF SLOPE OF END-SYSTOLIC PRESSURE-VOLUME LINE (Emax) OF IN SITU DOG HEART
- DIFFERENT EFFECTS OF GLOBAL AND REGIONAL ISCHEMIA ON LEFT VENTRICULAR REGIONAL FUNCTION : AN ANALYSIS BY WALL TENSION-AREA RELATION : Cardiac Function (II) : FREE COMMUNICATIONS (IV) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRC
- IS REGIONAL VENTRICULAR WALL WORK DETERMINED FROM REGIONAL FORCE AND SHORTENING ALWAYS CONSISTENT WITH THE LAW OF CONSERVATION OF ENERGY?
- OXYGEN CONSUMPTION AND PRESSURE-VOLUME AREA OF ABNORMAL CONTRACTIONS IN CANINE HEART : Cardiac Function (III) : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- CONTRACTILITY AND OXYGEN CONSUMFTION OF CANINE LEFT VENTRICLE : SYSTOLIC PRESSURE VOLUME AREA (PVA) : Cardiac Function (III) : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- QUANTITATIVE ANALYSIS OF LEFT VENTRICULAR REGIONAL WORK BY WALL TENSION-AREA RELATION : Cardiac Function(II) : II : 48 Annual Scientific Meeting, Japanese Circulation Society
- Dissociation of End Ejection from End Systole of Ventricle
- No Suppression of Respiratory Function of Mitochondria Isolated from the Hearts of Anesthetized Rats with High-Dose Pentobarbital Sodium
- Positive Feedback Hypothesis on Development of Essential Hypertension
- Principle of Normal Heart Adaptation in Size and Weight to Pressure and Volume Loads
- Principle of Adaptation of Heart Size to Volume Load : A Theoretical Approach
- Calcium kinetics and energetics in myocardium. Simulation study.
- Energetics of the time-varying elastance model, a visco-elastic model, Matches Mommaerts' unifying concept of the fenn effect of muscle.
- Intact chordae tendineae increase ventricular volume measurement error by the balloon method.
- Cardiac Output in Conscious SHR
- Erratum: Preparation of New Nitrogen-Bridged Heterocycles 72. A New Approach to 1-Acyl-3-(substituted methylthio)thieno[3′,4′:4,5]imidazo[1,5-a]pyridine Derivatives [Chem. Pharm. Bull. 58(11): 1502-1510 (2010)]
- Analytical Expression of Effective Afterload in Aortic and Mitral Regurgitation.
- Paul Dudley White International Lecture: Cardiac Performance as Viewed Through the Pressure-Volume Window.:Cardiac Performance as Viewed Through the Pressure-Volume Window
- Crossbridge model compatible with the linear relation between left ventricular oxygen consumption and pressure-volume area.