Preparation of New Nitrogen-Bridged Heterocycles. 45. Smooth Hydrolysis of 6-Membered Heterocyclic 2-Imines with Partial Aromaticity
スポンサーリンク
概要
- 論文の詳細を見る
The treatment of 2H-pyrano[2,3-b]indolizin-2-imines and 2H-thiino[3,2-a]indolizin-2-imines with acetic acid at reflux temperature smoothy afforded the corresponding 2H-pyrano[2,3-b]indolizin-2-one and 2H-thiino[3,2a]indolizin-2-one derivatives in moderate to good yields. An X-ray analysis of a 2H-thiino[3,2-a]indolizin-2-one derivative was also performed.
- 公益社団法人日本薬学会の論文
- 1998-10-15
著者
-
Suga Hiroyuki
Department Of Cardiovascular Dynamics National Cardiovascular Center Research Institute
-
Akikazu Kakehi
Department Of Chemistry And Material Engineering Faculty Of Engineering Shinshu University
-
Kakehi Akikazu
Department Of Chemistry And Material Engineering Faculty Of Engineering Shinshu University
-
Suga Hiroyuki
Department Of Chemistry And Material Engineering Faculty Of Engineering Shinshu University
-
Kakehi A
Dep. Of Chemistry And Material Engineering Fac. Of Engineering Shinshu Univ. Wakasato Nagano 380-855
-
Takano S
Department Of Chemistry And Material Engineering Faculty Of Engineering Shinshu University
-
ITO Suketaka
Department of Chemistry and Material Engineering, Faculty of Engineering, Shinshu University
-
HIRATA Kazuyuki
Department of Chemistry and Material Engineering, Faculty of Engineering, Shinshu University
-
TAKANO Satoshi
Department of Chemistry and Material Engineering, Faculty of Engineering, Shinshu University
-
Suga H
Dep. Of Chemistry And Material Engineering Fac. Of Engineering Shinshu Univ. Wakasato Nagano 380-855
-
Takano Satoshi
Department Of Chemistry And Material Engineering Faculty Of Engineering Shinshu University
-
Ito Suketaka
Department Of Chemistry And Material Engineering Faculty Of Engineering Shinshu University
-
HIRATA Kazumi
Department of Physical Chemistry, Osaka University of Pharmaceutical Sciences
-
Hirata K
Department Of Physical Chemistry Osaka University Of Pharmaceutical Sciences
-
SUGA Hiroyuki
Department of Cardiac Physiology, National Cardiovascular Center Research Institute
-
Ito Suketaka
Department of Applied Chemistry Faculty of Engineering Nagoya University
関連論文
- A New Approach to Imidazo[1,2-a]pyridine Derivatives and Their Application to the Syntheses of Novel 2H-Pyrano[2’,3’:4,5]imidazo[1,2-a]pyridin-2-one Derivatives
- Synthesis of Spiro[2-cyclopentene-1,3’-imidazo[1,2-a]pyridine] Derivatives and Their Interesting Behavior in 1H-NMR Spectra in Deuteriochloroform
- Synthesis and Reactions of 3-Ethynyl-2-(Triphenylphosphoimino)-1-azaazulenes
- Preparation of New Nitrogen-Bridged Heterocycles 67. Syntheses of α,α′-Bis[(thieno[3,4-b]indolizin-3-yl)thio]-o-, m-, and p-xylene Derivatives and Their Conformational Structures
- Preparation of New Nitrogen-Bridged Heterocycles. 60. Syntheses and Conformational Analyses of Bis(indolizin-1-yl) Disulfides
- Preparation of New Nitrogen-Bridged Heterocycles. 59. Syntheses and Intramolecular Interactions of 3-(Acylmethylthio)- and 3-[(3-Ethoxycarbonyl-2-propenyl)thio] thieno [3,4-b] indolizine Derivatives
- Reactions of 8-(Triphenylphosphoimino)quinoline with Aryl Aldehydes and Aryl Isocyanates : Formation of 2-Aryl-4H-imidazo[4,5,1-ij]quinolines and Related Systems
- Preparation of New Nitrogen-Bridged Heterocycles. 55. Reinvestigation of the Bromination/Dehydrobromination of Ethyl 3-[2-(Methylthio)indolizin-3-yl] acrylate Derivatives
- Preparation of New Nitrogen-Briged Heterocycles. 49. A New Access to Thieno[3,4-b]indolizine Derivatives
- Mode of frequency distribution of external work efficiency of arrhythmic beats during atrial fibrillation remains normal in canine heart
- High Mechanical Efficiency of Left Ventricular Arrhythmic Contractions during Atrial Fibrillation
- Variable Unstressed Volume Keeps Normal Distributions of Canine Left Ventricular Contractility and Total Mechanical Energy under Atrial Fibrillation
- Predictability of O_2 Consumption from Contractility and Mechanical Energy of Absolute Arrhythmic Beats in Canine Heart
- Exponential Fitting of Postextrasystolic Potentiation May Underestimate the Cardiac Ca^ Recirculation Fraction : A Theoretical Analysis
- Myocardial protective effects of University of Wisconsin Solution (UWS), Celsior, and St.Thomas' Hospital Solution (STH) on postischemic donor heart performance
- Cardiovascular Beneficial Effects of Electroacupuncture at Neiguan (PC-6) Acupoint in Anesthetized Open-Chest Dog
- New Index for Oxygen Cost of Contractility from Curved End-Systolic Pressure-Volume Relations in Cross-Circulated Rat Hearts
- Hybrid Logistic Characterization of Isometric Twitch Force Curve of Isolated Ferret Right Ventricular Papillary Muscle
- Effects of Myosin Isozyme Shift on Curvilinearity of the Left Ventricular End-Systolic Pressure-Volume Relation of In Situ Rat Hearts
- Pressure-Interval Relationship Characterizes Left Ventricular Irregular Beat Contractilities and Their Mean Level during Atrial Fibrillation
- Sinusoidal and Exponential Decays of Postextrasystolic Transient Alternans in Excised Blood-Perfused Canine Hearts
- Reactions of 2-Triphenylphosphoimino-1-azaazulenes with Aryl Isocyanates and Aryl Isothiocyanates
- Postextrasystolic Contractility Normally Decays in Alternans in Canine In Situ Heart
- Validity of transeient Ees compared with stable Ees
- Frequency Distribution, Variance, and Moving Average of Left Ventricular Rhythm and Contractility during Atrial Fibrillation in Dog
- Frank-Starling Mechanism Retains Recirculation Fraction of Myocardial Ca^ in the Beating Heart
- Effective Arterial Elastance of Irregular Beats during Atrial Fibrillation in Canine Left Ventricle
- Preparation of New Nitrogen-Bridged Heterocycles 72. A New Approach to 1-Acyl-3-(substituted methylthio)thieno[3′,4′:4,5]imidazo[1,5-a]pyridine Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 56. Syntheses and Reactions of 1-[2,2-Bis(alkylthio)-1-(ethoxycarbonylacetyl)vinyl]pyridinium Salts
- Enantio-and Diastereoselectivity in 1,3-Dipolar Cycloaddition Reactions of Nitrones with 3-Crotonoyl-2-oxazolidinone Catalyzed by Ni(II)-Binaphthyldiimine Complexes
- Asymmetric Cyclopropanation and Aziridination Reactions of Olefins Catalyzed by Cu(I)-Binaphthyldiimine Complexes
- A Through-Space Interaction of 3-Benzylthiothieno[3,4-b]indolizine Derivatives Combined by a Highly Flexible Spacer
- Preparation of New Nitrogen-Bridged Heterocycles.51.^ Syntheses and Structures of Compounds Having Two Indolizine Nuclei in a Molecule
- Stereocontrol in a Ytterbium Triflate-Catalyzed 1,3-Dipolar Cycloaddition Reaction of Carbonyl Ylide with N-substituted Maleimides and Dimethyl Fumarate
- Preparation of New Nitrogen-bridged Heterocycles(50)Syntheses of Some Heterocyclic Compounds Starting from Pyridinium 1-(Ethoxycarbonylacetyl)methylides
- Preparation of New Nitrogen-bridged Heterocycles(47)Reactions of 2-Indolizinethiolates with Acetylenic Compounds
- Preparation of New Nitrogen-Bridged Heterocycles. 46. Selective Formation of 4(1H)-8,8a-Dihydro-1,4-thiazino[3,4,5-cd]indolizinone and (E)-3-(1,3-Oxathiol-2-ylidene)-2(3H)-indolizinone Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 45. Smooth Hydrolysis of 6-Membered Heterocyclic 2-Imines with Partial Aromaticity
- Ryanodine Decreases Internal Ca^ Recirculation Fraction of the Canine Heart as Studied by Postextrasystolic Transient Alternans
- 2, 3-Butanedione Monoxime Suppresses Excitation-Contraction Coupling in the Canine Blood-Perfused Left Ventricle
- Preparation of New Nitrogen-Bridged Heterocycles. 68. One-Pot Synthesis of 4-Substituted 5-Acylthieno[3,2-d]thiazole Derivatives
- Synthesis of 2, 5-Dihydro-1, 2, 4-oxadiazoles through Formal [3+2] Cycloaddition of Oxazoles with Nitrosobenzene Derivatives
- Regio-Control of Formal [3 + 2] Cycloadditions of 5-Alkoxyoxazoles with Diethyl Oxomalonate
- Chiral 2, 2′-Binaphthyldiimine-Nickel(II) Complexes as Lewis Acid Catalysts for Enantioselective Diels-Alder Reactions
- Asymmetric Diels-Alder Reactions Catalyzed by Chiral Ni(II)-Binaphthyldiimine Complexes
- CANINE RIGHT VENTRICULAR MECHANICAL WORK AND OXYGEN CONSUMPTION : APPLICATION OF PVA TO THE RIGHT VENTRICLE : Cardiac Function (III) : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- Preparation of New Nitrogen-Bridged Heterocycles. 58. : Syntheses and Intramolecular Arene-π Interactions of 3-(Allylthio)- and 3-(Propargylthio)thieno[3,4-b]indolizine Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 54. Increased Arene-Arene Interactions of 3-(Bicyclic and Tricyclic Arylmethylthio)thieno[3,4-b]indolizine Derivatives
- Preparation of New Nitrogen-Bridged Heterocycles. 53. Syntheses of 3-(Benzylthio)thieno[3,4-b]indolizine Derivatives and Their Intramolecular Arene-Arene Interactions
- Linear O_2 Use-Pressure-Volume Area Relation from Curved End-Systolic Pressure-Volume Relation of the Blood-Perfused Rat Left Ventricle
- DENOPAMINE (BETA_1-SELECTIVE ADRENERGIC RECEPTOR AGONIST) AND ISOPROTERENOL (NON-SELECTIVE BETA-ADRENERGIC RECEPTOR AGONIST) EQUALLY INCREASE HEART RATE AND MYOCARDIAL OXYGEN CONSUMPTION IN DOG HEART
- -0217-O_2 CONSUMPTION DURING VENTRICULAR FIBRILLATION IN COOLING CAN BE ACCOUNTED FOR BY EQUIVALENT PRESSURE-VOLUME AREA
- -0209-DECREASED CONTRACTILITY AND INCREASED ENERGETIC COST OF CONTRACTILITY IN STUNNED MYOCARDIUM
- -0204-THE EFFECTS OF DYNAMIC CARDIAC COMPRESSION ON VENTRICULAR ENERGETICS
- -372-EFFECTS OF BLOOD-BORN CATECHOLAMINES ON LEFT VENTRICULAR Emax AND OXYGEN CONSUMPTION IN THE EXCISED CROSSCIRCULATED DOG HEART : Ventricular Function : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULA
- -126-DOSE A CALCIUM SENSITIZER, DPI 201-106, IMPROVE MYOCARDIAL EFFICIENCY IN DOG LEFT VENTRICLE? : COMPARISON TO EPINEPHRINE : Cardiovascular Drugs : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION S
- Relationship between parameters of the urea kinetic model and serum amino acid levels in patients on hemodialysis
- Unexpected formation of thiino[3',4':4,5]oxazolo[1,3-b][1,3]oxazepine derivatives
- Facile synthesis of (2-Benzimidazolyl)-1-azaazulenes, (2-Benzothiazolyl)-1-azaazulenes, and related compounds and evaluation of their anticancer in vitro activity
- Facile synthesis of (2-benzimidazolyl)-1-azaazulenes, (2-benzothiazolyl)-1-azaazulenes, and related compouds and evaluation of their anticancer in vitro activity
- Synthesis of Aryl Conjugated (1-Azaazulenyl)acetylenes and Facile Synthesis of Thiophene Fused 1-Azaazulenes
- Effective methods for introducing some aryl and heteroaryl substituent onto 1-azzazulene nuclei
- Reactions of 3-phenyl-8-triphenylphosphoimino-1-azaazulene with aryl isocyanate, aryl isothiocyanate, and carbon disulfide
- Synthesis of 2-chloro-8-(2-pyridyl)-1-azaazulene and its metal complexes
- Generation and reactions of 3-phenyl-7,8-dehydro-1-azaazulene
- First synthesis and cycloaddition reactions of 1-azaazulene N-ylide
- Hybrid Logistic Characterization of Isometric Twitch Force-Time Curve of Intact Blood-Perfused Canine Right Ventricular Papillary Muscle
- Effects of Ca^ and Epinephrine on Ca^ Recirculation Fraction and Total Ca^ Handling in Canine Left Ventricles
- Effects of Intracoronary Caffeine on Left Ventricular Mechanoenergetics in Ca^ Overload Failing Rat Hearts
- Left Ventricular Mechanoenergetics under Altered Coronary Perfusion in Guinea Pig Hearts
- Synthesis and some reactions of ethyl (2-alkylimino-1,2-dihydro-1-azaazulen-1-yl)acetates
- Synthesis and reactions of 3- and 8-ethynyl-1-azaazulenes
- Thermolysis of Ethoxycarbonyl[2-phenyl-2-(phenylsulfonylhydrazono)ehyl]methylenetriphenylphosphoranes. Formation of Substituted Pyridazinones
- Reductive cyclization of 8-(2-nitrophenyl)-1-azaazulene derivatives; formation of 6a,7-diazanaphth[3,2,1-cd]azulene and 7H-1,7-diazaindeno[1,2-e]azulene systems, a new DNA intercalater
- NORMALIZATION OF END-SYSTOLIC PRESSURE-VOLUME RELATION AND Emax OF DIFFERENT SIZED HEARTS
- Digital On-Line Computation of a Predictor of Cardiac Oxygen Consumption : Left Ventricular Systolic Pressure Volume Area
- Hemodynamics of Experimentally Hypertensive Rats in Conscious and Anesthetized States
- Degradational Cyclization of α-[2-Phenyl-2-(phenylsulfonylhydrazono)ethyl]phenacylidenetriphenylphosphoranes to 3,6-Diphenylpyridazines and 5-Benzoyl-3-phenylpyrazoles
- Real Time Analog Computation of Left Ventricular Systolic Pressure Volume Area as Predictor of Oxygen Consumption
- Factors Delaying End Ejection from End Systole of Ventricle
- Correlative Changes in Total Vascular Capacity and Resistance in Carotid Sinus Reflex
- Effect of Increasing Age on Hemodynamics of Spontaneously Hypertensive Rats
- Hemodynarnics of Spontaneously Hypertensive Rats in Conscious State
- -150-MECHANISMS OF HYPERKINESIS IN NONISCHEMIC REGION OF ACUTE ISCHEMIC CANINE HEART
- -139-ASSESSMENT OF SLOPE OF END-SYSTOLIC PRESSURE-VOLUME LINE (Emax) OF IN SITU DOG HEART
- DIFFERENT EFFECTS OF GLOBAL AND REGIONAL ISCHEMIA ON LEFT VENTRICULAR REGIONAL FUNCTION : AN ANALYSIS BY WALL TENSION-AREA RELATION : Cardiac Function (II) : FREE COMMUNICATIONS (IV) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRC
- IS REGIONAL VENTRICULAR WALL WORK DETERMINED FROM REGIONAL FORCE AND SHORTENING ALWAYS CONSISTENT WITH THE LAW OF CONSERVATION OF ENERGY?
- OXYGEN CONSUMPTION AND PRESSURE-VOLUME AREA OF ABNORMAL CONTRACTIONS IN CANINE HEART : Cardiac Function (III) : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- CONTRACTILITY AND OXYGEN CONSUMFTION OF CANINE LEFT VENTRICLE : SYSTOLIC PRESSURE VOLUME AREA (PVA) : Cardiac Function (III) : III : 48 Annual Scientific Meeting, Japanese Circulation Society
- QUANTITATIVE ANALYSIS OF LEFT VENTRICULAR REGIONAL WORK BY WALL TENSION-AREA RELATION : Cardiac Function(II) : II : 48 Annual Scientific Meeting, Japanese Circulation Society
- Dissociation of End Ejection from End Systole of Ventricle
- Reaction of 2-chloro-1-azaazulene with diphenylcyclopropenone; Dimerization of the cycloadduct attended by cine-substitution and rearrangement
- No Suppression of Respiratory Function of Mitochondria Isolated from the Hearts of Anesthetized Rats with High-Dose Pentobarbital Sodium
- Synthesis and some reactions of 1,8-diamino-1-azaazulenium salts
- Positive Feedback Hypothesis on Development of Essential Hypertension
- Principle of Normal Heart Adaptation in Size and Weight to Pressure and Volume Loads
- Principle of Adaptation of Heart Size to Volume Load : A Theoretical Approach
- Reaction of 2-hydrazino-1-azaazulene with diphenylnitrone : unexpected formation of phenylimino-p-benzoquinone-N-oxide
- NOVEL REARRANGEMENTS OF A 8aH-PYRIDO〔1,2-d〕THIENO〔2’,3’-b〕〔1,4〕THIAZEPINE DERIVATIVE
- MOLECULAR RECOGNITION OF 2-(ARYLMETHYLTHIO)INDOLIZINE DERIVATIVES THROUGH AN INTRAMOLECULAR ARENE-π (CATION) INTERACTION (Dedicated to Dr. Albert Padwa on his 75th birthday)