Reproductive Performance in Diabetes Mice with a Special Reference to Uterine Natural Killer Cells and Placental Growth Factor
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概要
- 論文の詳細を見る
To determine the effect of diabetes on reproductive performance, two kinds of diabetes mice, i.e., KK/TaJcl mice with Type-II diabetes and Streptozotocin-induced diabetes mice with Type-I diabetes, were used in this study. Particular attention was paid to uterine natural killer (uNK) cells and placental growth factor (PlGF). The number of fetuses, the fetal and placental weights in both diabetes mice were significantly decreased when compared to controls. Surprisingly, uNK cells in both diabetes mice persisted in the metrial gland even at the term of pregnancy. Although PlGF expression in both diabetes mice was significantly decreased, PlGF protein did not change. These results show that diabetes condition affects reproductive performance, particularly uNK cell behavior, but not PlGF production.
- 社団法人 日本獣医学会の論文
著者
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SUGIYAMA Makoto
Department of Radiology, Hokuriku Hospital
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Rerkamnuaychoke Worawut
山口大学 大学院連合獣医学研究科
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Rerkamnuaychoke Worawut
Department Of Veterinary Medicine Kasetsart University
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Sugiyama Makoto
Department Of Radiology Hokuriku Hospital
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Hondo Eiichi
Laboratory Of Basic Veterinary Science United Graduate School Of Veterinary Science Yamaguchi Univer
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Hondo E
Yamaguchi Univ. Yamaguchi Jpn
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PHICHITRASILP Thanmaporn
The United Graduate School of Veterinary Science, Faculty of Agriculture, Yamaguchi University
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HONDO Eiichi
The United Graduate School of Veterinary Science, Faculty of Agriculture, Yamaguchi University
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WAKITANI Shoichi
The United Graduate School of Veterinary Science, Faculty of Agriculture, Yamaguchi University
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KISO Yasuo
The United Graduate School of Veterinary Science, Faculty of Agriculture, Yamaguchi University
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TERAKAWA Jumpei
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
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Phichitraslip Thanmaporn
The United Graduate School Of Veterinary Science Faculty Of Agriculture Yamaguchi University
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Sugiyama Makoto
Department Of Biotechnology Faculty Of Engineering Nagoya University
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Rerkamnuaychoke Worawut
Department Of Anatomy Faculty Of Veterinary Medicine Kasetsart University
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WAKITANI Shoichi
The United Graduate School of Veterinary Science, Yamaguchi University
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PHICHITRASILP Thanmaporn
The United Graduate School of Veterinary Science, Yamaguchi University
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