Augmentation of the Pharmacological Action of Corydalis Tuber by Saussurea Root in Isolated Mouse Ileum
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概要
- 論文の詳細を見る
To understaqnd the meaning of blending crude drugs in Chinese medicinal prescriptions, the influence of Saussurea root on the pharmacological action of Corydalis tuber was examined. Saussurea root increased the depression of acetylcholine-induced contraction caused by the hot water extract solution of Corydalis tuber in mouse ileum at low dosage, which showed no direct influence on acetylcholine. Dehydrocostuslactone in Saussurea root was characterized as the component having increasing activity and the relationship between the concentration of acetylcholine and the variation in the contraction depressed by Corydalis tuber alone or a mixture of the Corydalis tuber and dehydrocostuslactone was investigated for clarification of the mode of action.
- 公益社団法人 日本薬学会の論文
- 2001-08-01
著者
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Kobayashi Kyoko
Tohoku Pharmaceutical Univ. Miyagi Jpn
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YOSHIZAKI Fumihiko
Tohoku Pharmaceutical University
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Yoshizaki Fumihiko
Tohoku College Of Pharmacy
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Takahashi R
Tohoku Pharmaceutical Univ. Sendai Jpn
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Honma Akira
Tohoku Pharmaceutical University
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MOTOHARA Tae
Tohoku Pharmaceutical University
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TAKAHASHI Ryo
Tohoku Pharmaceutical University
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AIHARA Miwa
Tohoku Pharmaceutical University
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SUDO Teppei
Tohoku Pharmaceutical University
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Kobayasi Kyouko
Tohoku Pharmaceutical University
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