尿浸潤に關スル實驗的研究 : 第5編 尿ノ蟇心臟ニ及ボス影響ニ就テ
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1) 30 bull-frogs of nearly the same weight recieved injections subcutaneously in their thighs of 0.1 to 5.0 cubic centimetres of healthy human or rabbit urine, which varied in its reaction, concentration and specific weight, and partly unfiltered and partly filtered with Berkefeld's filter. 2) 45 bull-frogs were given injections of 0.1 to 5.0 cubic centimetres intravenously as much as possible under the same conditions. The physiological beating of the hearts of the bull-frogs was previously recorded on sooted paper after Engelman's method and the curve was compared before and after the injection. 3) 30 excised hearts of bull-frogs perfused with Ringer's solution after Lang- endorff's method recieved injections of 0.1 to 5.0 cubic centimetres through a rubber tube led into an auricle with a glass cannula. 4) 20 bull-frogs recieved injections of 0.1 to 5.0 cubic centimetres of physiological salt solution, human and rabbit serum respectively. The results were as follows: a) The physiological beating of the heart of bull-frogs went on unaltered under the administration of small quantities (under 0.3 cubic centimetres) of human or rabbit urine, but it was lessend at 1.0 to 3.0 cubic centimetres in various degrees and was sometimes accelerated temporarily after the restraint of the beating. When the quantity was larger than approximately 4.0 cubic centimetres the beating was stopped entirely. b) Nothing was proved to depend upon the reaction, concentration, specific wreight etc. of the urin so far as the activity of the heart is concerned. c) The ventricle was always more strongly influenced and for a longer time than the auricle.
- 京都府立医科大学の論文
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