Multiscale Polyp Segmentation Algorithm in CT Colonography(International Forum on Medical Imaging in Asia 2009 (IFMIA 2009))
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概要
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An automatic polyp segmentation algorithm in CT colonography is presented. This algorithm can provide quantitative measurement of polyp size which is used as the biomarker of malignancy. Hessian matrix is the square matrix of second partial derivatives of a scalar-valued function and is well known for object recognition in computer vision and medical shape analysis. We applied this multiscale Hessian classification method to polyp segmentation in CTC. The overall segmentation scheme is performed by following procedures. First, multiscale blob-likeness filter output images were produced. Second, the voxel which has the local maximum of blob-likeness value was selected as initial seed point in the following region growing process. Third, the region growing algorithm was applied to make initial polyp region. And the output region was dilated to include outside partial volume effect region. After the polyp region was extracted, the principle component analysis (PCA) was performed to find principle axis. According to this principle axis the sizes of polyps were measured automatically. For evaluation 6 anthropomorphic pig phantoms were prepared. There were 82 artificial polyps with different sizes and shapes. The results of computerized measurement were compared to that of manual ex-vivo measurement with vernier calipers. Linear regression was performed, and the result was "y=2.82+0.79x". Two groups were statistically correlated (p<0.001).
- 2009-01-12
著者
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Lee June-Goo
Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Me
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Kim Jong
Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Me
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Kim Se
Department of Radiology, Seoul National University Hospital
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Kim Jong
Inter-university Semiconductor Research Center Seoul National University:school Of Electrical Engine
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Kim Jong
Seoul National Univ. Seoul Kor
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Lee June‐goo
Seoul National Univ. Coll. Medicine
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Lee June-goo
Interdisciplinary Program In Radiation Applied Life Science Seoul National University College Of Med
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Kim Se
Seoul National Univ. Hospital Seoul Kor
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Kim Se
Department Of Anatomy College Of Veterinary Medicine Chonnam National University
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Kim Jong
Inter-University Semiconductor Research Center and School of Electrical Engineering and Computer Science, Seoul National University, San 56-1, Sillim-dong, Gwanak-ku, Seoul 151-742, Republic of Korea
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