1433 DNA自己集合化パターンの反応拡散波モデル(S38-1 ナノフルイズ,S38 マイクロ・ナノフルイズ)

概要

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Reaction-diffusion system by Alan Turing (1952) is analyzed for simulation of self-assembled network of 50bp poly(dA)・poly(dT) DNA on mica surface. The theoretical model is well used in the research area of morphogenesis, for example, markings or stripe patterns on animal skin, and the experimental data for validation are accumulated very recently. The comparison of the network pattern between the experimental results using an atomic force microscopy and the simulated results of reaction-diffusion system is made in detail for various conditions. They are in good agreement although the theoretical model is very simple. The result suggests not only the possibility of the prediction tool in the bionanotechnology using DNA but the good example that such a heuristics approach is very significant to understand the behaviors of macromolecules or the complex system.
一般社団法人日本機械学会の論文
2007-09-07