Two New Sesquiterpenoids and Two New Prenylated Phenylpropanoids from Illicium fargesii, and Neuroprotective Activity of Macranthol
スポンサーリンク
概要
- 論文の詳細を見る
Two new seco-prezizaane-type sesquiterpenoids 1, 2 and two new prenylated phenylpropanoids 4, 5 were isolated along with 15 known compounds from Illicium fargesii. The structures of 1, 2 were elucidated as 10-O-(E)-and 10-O-(Z)-cinnamoyl-2-oxo-6-deoxyneoanisatin by analysis of spectroscopic data and by comparison of their NMR data with those of previously reported 2-oxo-6-deoxyneoanisatin (3), respectively, whereas the structures of 4, 5 were identified as 4-allyl-2-(3-methylbut-2-en-1-yl)phenol and 4-allyl-2-(2-methylbut-3-en-2-yl)phenol, respectively, on the basis of spectroscopic data. Among the isolated compounds, macranthol (7) was found to have neuroprotective activity at 5-10μM in rat cortical neurons cultured in DMEM/N_2 medium.
- 公益社団法人日本薬学会の論文
- 2008-08-01
著者
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福山 愛保
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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福山 愛保
徳島文理大薬
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FUKUYAMA Yoshiyasu
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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Huang Jian-mei
Faculty Of Pharmaceutical Sciences Beijing University Of Chinese Medicine
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児玉 三明
徳島文理大薬
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KUBO Miwa
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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MORIYAMA Miyako
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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YANG Chun-Shu
Faculty of Pharmaceutical Sciences, Beijing University of Chinese Medicine
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HARADA Kenichi
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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HIOKI Hideaki
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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Yang Chun-shu
Faculty Of Pharmaceutical Sciences Beijing University Of Chinese Medicine
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Fukuyama Yoshiyasu
Faculty Of Pharmaceutical Science Tokushima Bunri University
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Kubo Miwa
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Hioki Hideaki
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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Harada Kenichi
Faculty Of Pharmaceutical Science Tokushima Bunri University
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Moriyama Miyako
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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