A Formal Total Synthesis of Colchicine via the Scott's Intermediate. Palladium (0)-Mediated meta-Ethynylation of a Tropolone Derivative
スポンサーリンク
概要
- 論文の詳細を見る
Colchicine was formally synthesized from 4-hydroxytropolone in a few-step sequence. The key step of the synthesis is palladium (0)-catalyzed ethynylation of 4-(trifluoromesyloxy)-2-methoxytropone. The present method has a potential in synthesizing various structurally modified colchicine derivatives.
- 1995-11-15
著者
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Mori Ryoji
Graduate School Of Engineering Sciences 39 Kyushu University
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Takeshita H
Kyushu Univ.
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Takeshita Hitoshi
Tohwa University
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Takeshita Hitoshi
Tohwa Institute For Orient Studies Tohwa University
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Mori A
Department Of Synthetic Chemistry The University Of Tokyo
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