Relation of Aortic Distensibility and Pulse Wave Velocity to the Degree of Coronary Artery Stenosis

概要

論文の詳細を見る
We investigated the correlation of aortic compliance and aortic pulse wave velocity (PWV) with the degree of the coronary stenosis. Invasive-PWV (IPWX) measurements were carried out in 38 male and 11 female patients, ranging in age from 17 to 71 years old (mean age 54.4 years old). We measured IPWV in ascending, thoracic and abdominal aorta and also in whole aorta by using catheter-tip manometer during diagnostic catheterization and coronary angiography. Tarazi's index (pulse pressure/ stroke volume) and diastolic blood pressure decay (DBPD, Simon's method) were also measured as the indicator of the arterial compliance. Balcon's method and Gensini's method were used as the coronary stenotic indx (CSI). IPWVs in ascendig, thoracic and abdomonal aorta were 9.42±3.96m/sec, 7.34±2.17 m/sec and 8.42±2.43 m/sec, respectively and the thoracic aorta was the most compliant aorta. (p<0.05). IPWV was positively correlated with Tarazi's index (r=0.733, P<0.001) and was negatively, correlated with DBPD (r=-0.717, p<0.001). IPWV was correlated to CSI by Gensini and Balcon, respectively (r=0.568, p<0.001 and r=-0.671, p<0.001). In conclusion, IPWV was well correlated with other indices of arterial compliance and predicted the existence of the significant coronary stenosis. PWV was useful method to know the aortic characteristics in patients with arteriosclerosis.
神戸大学の論文
1996-01-31