Increased Urinary β2-microglobulin and Mortality Rate by Cause of Death in a Cadmium-polluted Area
スポンサーリンク
概要
- 論文の詳細を見る
To clarify the effect of environmental cadmium (Cd) exposure on the life prognosis of inhabitants living in a Cd-polluted area, the standardized mortality ratio (SMR) according to cause of death in urinary β2-microglobulin (β2-MG)-positive subjects (≥1000μg/gCr) was compared to that of the Japanese general population and β2-MG-negative subjects (<1000μg/gCr). The SMR for all causes of death of both sexes was higher than that of the Japanese general population and β2-MG-negative subjects. Among women, the SMR for malignant neoplasms was higher than that of β2-MG-negative subjects. For cardiovascular disease and cerebrovascular disease, especially heart failure and cerebral infarction, SMRs were significantly higher in both sexes. The SMR for renal diseases was significantly high in the men and tended to be high in the women. These results suggest that the prognosis of urinary β2-MG-positive subjects with Cd-induced renal tubular dysfunction is unfavorable, with higher mortality rates due to renal diseases, cerebral infarction and heart failure contributing to this. Although the increase of the mortality rate was slight, Cd might affect cancer mortality in women.
- 日本衛生学会の論文
著者
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Miura Katsuyuki
Department of Health Science, Shiga University of Medical Science
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城戸 照彦
School Of Health Sciences Kanazawa University
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Kido Teruhiko
金沢医科大学 健康増進予防医学
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河野 俊一
石川産業保健推進センター
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Nakagawa Hideaki
Department of Epidemiology and Public Health, Kanazawa Medical University
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MORIKAWA Yuko
Department of Public Health, Kanazawa Medical University
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KIDO Teruhiko
Department of Community Health Nursing, Kanazawa University
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NOGAWA Koji
Department of Hygiene, Chiba University School of Medicine
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NISHIJO Muneko
Department of Public Health, Kanazawa Medical University
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TABATA Masaji
Department of Public Health, Kanazawa Medical University
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TAKAHARA Hideyuki
Department of Public Health, Kanazawa Medical University
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OKUMURA Yoshiharu
Department of Public Health, Kanazawa Medical University
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YOSHITA Katsushi
Department of Public Health, Kanazawa Medical University
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KAWANO Shunichi
Department of Public Health, Kanazawa Medical University
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NISHI Masami
Ishikawa Prefecture Health Authority
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Nishijo M
Department Of Public Health Saitama Medical School
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三浦 克之
Dep. Of Health Sci. Shiga Univ. Of Medical Sci.
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Miura Katsuyuki
Department Of Applied Pharmacology And Therapeutics Osaka City University Medical School
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Miura Katsuyuki
Dep. Of Social Medicine Shiga Medical Univ.
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Nogawa K
Department Of Occupational And Environmental Medicine Graduate School Of Medicine Chiba University
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Tabata Masaji
Department Of Public Health Kanazawa Medical University
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西 正美
Department Of Epidemiology And Public Health Kanazawa Medical University
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Nakagawa H
Department Of Public Health Kanazawa Medical University
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Kawano Shunichi
Department Of Cardiovascular Medicine Kyushu University Graduate School Of Medical Sciences
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Okumura Yoshiharu
Department Of Public Health Kanazawa Medical University
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Takahara Hideyuki
Department Of Public Health Kanazawa Medical University
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Nishijo Muneko
Department Of Public Health Kanazawa Medical University
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Nishijo Muneko
Department Of Epidemiology And Public Health Kanazawa Medical University
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Yoshita Katsushi
Department Of Public Health Kanazawa Medical University
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Nakagawa Hideaki
Department Of Epidemiology And Public Health Kanazawa Medical University
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Kawano Shunichi
Department Of Public Health Kanazawa Medical University
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Nagai Masaki
Department Of Epidemiology And Public Health Kanazawa Medical University
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Morikawa Yuko
Department Of Public Health Kanazawa Medical University
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Morikawa Yuko
Department Of Epidemiology And Public Health Kanazawa Medical University
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Kawado Miyuki
Laboratory For Genotyping Development Center For Genomic Medicine Riken
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Nakagawa Hideaki
Department of Clinical Chemistry, Faculty of Pharmaceutical Sciences, Toho University
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