Synthesis of 2-Amino-2-deoxy-β-D-arabinofuranosyl Nucleosides
スポンサーリンク
概要
- 論文の詳細を見る
9-(2-Deoxy-2-amino-β-D-arabinofuranosyl) adenine (IIIa) and guanine (IIIb) were synthesized from the corresponding azide compounds (II) obtained by nucleophilic substitution of tosyloxy groups of 2'-O-p-toluensulfonyladenosine (Ia) and guanosine (Ib), respectively. Their antitumor activity against sarcoma-180 solid tumor and cytotoxic activity against HeLa-S_3 cells were determined.
- 社団法人日本薬学会の論文
- 1979-03-25
著者
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今井 良二
Fuji Medical Research Laboratory Kyowa Hakko Kogyo Co. Ltd.
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平田 正
Tokyo Research Laboratories Kyowa Hakko Kogyo Co. Ltd.
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佐藤 章
Kyowa Hakko Kogyo Co. Ltd. Tokyo Research Laboratories
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佐藤 章
Tokyo Research Laboratory
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中溝 喜博
Tokyo Research Laboratory Kyowa Hakko Kogyo Co. Ltd.
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