Ginseng Pretreatment Protects against Transient Global Cerebral Ischemia in the Rat : Measurement of Local Cerebral Glucose Utilization by [^<14>C]Deoxyglucose Autoradiography
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概要
- 論文の詳細を見る
The effect of ginseng on brain glucose metabolism has been determined in normal and transient cerebral ischemic rat using the autoradiographic [^<14>C]2-deoxyglucose method. Ginseng had no effect on local cerebral glucose utilization (LCGU) in normal rat. By contrast, in rats subjected to 30 min of four vessel occlusion, a significant reduction of LCGU was shown in parts of the cortex and striatum in comparison to the control group. One-week administration of ginseng at 200 mg/kg/d before the occlusion produced an improvement of LCGU compared with the untreated group. These findings indicate that ginseng has some protective effects against brain damage in transient global cerebral ischemia.
- 公益社団法人日本薬学会の論文
- 1996-04-15
著者
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Saji Hideo
Department Of Patho-functional Bioanalysis Graduate School Of Pharmaceutical Sciences Kyoto Universi
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Saji Hideo
茨城県立医療大学 放射線技術科学
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Magata Y
Photon Medical Research Center Hamamatsu University School Of Medicine:molecular Imaging Frontier Re
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Magata Yasuhiro
京都大学 医学研究科心臓血管外科学
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Magata Yasuhiro
浜松医科大学附属光量子医学研究センター
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IIDA Yasuhiko
Department of Bioimaging Information Analysis, Gunma University Graduate School of Medicine
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Magata Y
Laboratory Of Genome-bio Photonics Photon Medical Research Center Hamamatsu University School Of Med
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Yasuhiro Magata
Photon Medical Research Center Hamamatsu University School Of Medicine:molecular Imaging Frontier Re
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Choi Seok
Department of Physiology, Chosun University College of Medicine
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MAGATA Yasuhiro
Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto Univer
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YOSHIDA AKIRA
Mitsubishi Kyoto Hospital
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YOKOYAMA Akira
Department of Radiopharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Kyoto Univeristy
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Ida Yuko
Department Of Applied Pharmacology Graduate School Of Medicine And Pharmaceutical Sciences Universit
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Choi S
Department Of Radiopharmaceutical Chemistry Faculty Of Pharmaceutical Science Kyoto University
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Ishii Yasushi
Third Division Dept. Of Internal Medicine And Nuclear Medicine
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Iida Y
Department Of Bioimaging Medical Sciences Gunma University
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Iida Yasuhiko
Department Of Bioimaging Medical Sciences Gunma University
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Iida Yasuhiko
Department Of Radiopharmaceutical Chemistry Faculty Of Pharmaceutical Sciences Kyoto University
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Yokoyama A
Biomedical Imaging Research Center Fukui Medical School
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Magata Yasuhiro
Department Of Nuclear Medicine Graduate School Of Medicine
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Yokoyama Akira
Department Of Internal Medicine Niigata Cancer Center Hospital
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Miyake Yoshinori
Department Of Radiology And Nuclear Medicine National Cardiovascular Center
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Yamamuro Masaki
Department Of Diagnostic Imaging And Nuclear Medicine Kyoto University Graduate School Of Medicine
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Saji Hideo
Dep. Of Patho-functional Bioanalysis Graduate School Of Pharmaceutical Sciences Kyoto Univ.
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Yokoyama Akira
Biomedical Imaging Research Center Fukui Medical School
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Sakahara H
Kyoto Univ. School Of Medicine
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Ishii Yasushi
Department Of Radiology Kyoto University School Of Medicine
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Saji Hideo
Department Of Cardiology Matsushita Memorial Hosipital
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Choi Seok
Department Of Physiology College Of Medicine Chosun University
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Ishii Yasushi
Department Of Patho-functional Bioanalysis Graduate School Of Pharmaceutical Sciences Kyoto Universi
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Yokoyama Akira
Department Of Animal Breeding Faculty Of Agriculture Nagoya University
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Yokoyama Akira
Department Of Radiopharmaceutical Chemistry Faculty Of Pharmaceutical Science Kyoto University
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Choi Seok
Department Of Information And Communications Kwangju Institute Of Science And Technology
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