Studies of the Active Substances in Herbs Used for Hair Treatment. II.Isolation of Hair Regrowth Substances, Acetosyringone and Polyporusterone A and B, from Polyporus umbellatus Fries
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概要
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Fractionation of the 50% ethanol extract of Polyporus umbellatus Fries by column chromatography on Amberlite XAD-2,silica gel, Sephadex LH-20 and octadecyl silica gel (ODS) (C18) monitored by a hair-regrowth activity assay, afforded three active principles, 1,2 and 3. The structures of 1,2 and 3 were determined as acetosyringone, polyporusterone A, and polyporusterone B by comparison of their spectral data with that of authentic samples, respectively. The effects of several compounds related to acetosyringone, 3,4-dihydroxybenzaldehyde or polyporusterone A on hair regrowth were also investigated.
- 公益社団法人日本薬学会の論文
- 1999-11-15
著者
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辻 浩一
Microbiological Research Institute Otsuka Pharmaceutical Co. Ltd.
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Tsuji Kiyoshi
Medicinal Chemistry Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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ISHIDA HITOSHI
School of Pharmaceutical Science, University of Shizuoka
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TSUJI KUNIRO
School of Pharmaceutical Science, University of Shizuoka
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INAOKA Yasunori
Pola R & D Laboratories, Pola Corporation
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FUKUSHIMA Makoto
Pola R & D Laboratories, Pola Corporation
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FUKUSHIMA Mitsuo
Department of Health Informatics Center Foundation for Biomedical Research and Innovation
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Tsuji K
School Of Pharmaceutical Science University Of Shizuoka
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辻 京子
Faculty Of Pharmaceutical Sciences Setsunan University
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INAOKA Yasunori
Laboratories, Pola Corporation
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SHIBATANI Jun-ichi
Pola R & D Laboratories, Pola Corporation
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Ishida Hitoshi
Research Institute For Bioresources Okayama University:(present Office)plant Protection Station Moji
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Inaoka Y
Laboratories Pola Corporation
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Shibatani Jun-ichi
Laboratories Pola Corporation
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