Isolation of Inhibitors of TPA-Induced Mouse Ear Edema from Hoelen, Poria cocos

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概要

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• Triterpene carboxylic acids were isolated from the methanol extract of Hoelen, Poria cocos, and found to inhibit 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced mouse ear edema. Their chemical structures were identified as 3β, 16α-dihydroxylanosta-7,9(11), 24-trien-21-oic acid, 16α-hydroxydehydropachymic acid, 16α-hydroxytrametenolic acid and dehydrotumulosic acid.

• 公益社団法人日本薬学会の論文
• 1996-04-15

著者

• 辻 浩一

  Microbiological Research Institute Otsuka Pharmaceutical Co. Ltd.

• Ishida H

  School Of Pharmaceutical Science University Of Shizuoka

• Tsuji Kiyoshi

  Medicinal Chemistry Research Laboratories Fujisawa Pharmaceutical Co. Ltd.

• Nukaya Haruo

  School of Pharmaceutical Sciences, University of Shizuoka

• ISHIDA HITOSHI

  School of Pharmaceutical Science, University of Shizuoka

• TSUJI KUNIRO

  School of Pharmaceutical Science, University of Shizuoka

• FUKAZAWA Hirotatsu

  School of Pharmaceutical Science, University of Shizuoka

• YAMASHIRO Hirokazu

  School of Pharmaceutical Sciences, University of Shizuoka

• Tsuji K

  School Of Pharmaceutical Science University Of Shizuoka

• 辻 京子

  Faculty Of Pharmaceutical Sciences Setsunan University

• Nukaya H

  School Of Pharmaceutical Science University Of Shizuoka

• Nukaya Haruo

  School Of Pharmaceutical Science University Of Shizuoka

• Ishida Hitoshi

  Research Institute For Bioresources Okayama University:(present Office)plant Protection Station Moji

• Fukazawa H

  Department Of Bioactive Molecules National Institute Of Infectious Diseases

• Yamashiro Hirokazu

  School Of Pharmaceutical Sciences University Of Shizuoka

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