In Vitro Inducible Nitric Oxide Synthesis Inhibitors from Alismatis Rhizoma
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概要
- 論文の詳細を見る
Bioassay-guided fractionation of an aqueous extract of Alismatis Rhizoma has furnished two inducible nitric oxide synthase (iNOS) inhibitory compounds, alismol (1) and alisol B monoacetate (2), together with an inactive triterpene, alisol C monoacetate (3). Compounds 1 and 2 inhibited nitric oxide (NO) synthesis in a dose-dependent manner in murine macrophage-like RAW 264.7 cells stimulated with interferon-γ (IFN-γ) plus lipopolysaccharide (LPS). The inhibitory effects of 1 and 2 on NO synthesis were partly due to suppression of iNOS mRNA expression as determined by Northern blotting.
- 社団法人日本薬学会の論文
- 1999-10-15
著者
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KIM Na-Young
College of Pharmacy, Kyung-Hee University
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Kim Youn-chul
College Of Pharmacy Wonkwang University
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Kim Youn-chul
中華人民共和国
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Kim Youn-chul
Coll. Of Pharmacy Wonkwang Univ.
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PAE Hyun-Ock
Department of Microbiology and Immunology, Wonkwang University School of Medicine
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CHUNG Hun-Taeg
Department of Microbiology and Immunology, Wonkwang University School of Medicine
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Pae Hyun-ock
韓国
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Pae Hyun-ock
Department Of Microbiology And Immunology Wonkwang University School Of Medicine
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Pae Hyun-ock
Medical Resources Research Center Of Wonkwang University
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Chung Hun-taeg
Department Of Microbiology And Immunology Wonkwang University School Of Medicine
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Chung Hun-taeg
Department Of Immunology Medical Resources Research Institute Wonkwang University
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Chung Hun-taeg
Medical Resources Research Center Of Wonkwang University
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Chung Hun-taeg
Genomic Research Center For Immune Disorders Wonkwang University School Of Medicine
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Sohn Dong-hwan
韓国
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Kim Na-young
Medicinal Resources Research Center(mrrc)of Wonkwang University
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KANG Tai-Hyun
College of Pharmacy, Wonkwang University
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CHOI Byung-Min
Department of Microbiology and Immunology, Wonkwang University School of Medicine and Medicinal Reso
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MYUNG Seung-Woon
Bioanalysis and Biotransformation Reseach Center, Korea Institute of Science and Technology
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SONG Yun-Seon
Bioanalysis and Biotransformation Reseach Center, Korea Institute of Science and Technology
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SHON Dong-Hwan
College of Pharmacy, Wonkwang University
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Myung Seung-woon
Bioanalysis And Biotransformation Reseach Center Korea Institute Of Science And Technology
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Myung Seung-woon
韓国
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Kang Tai-hyun
College Of Pharmacy Wonkwang University
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Choi Byung-min
Medicinal Resources Research Center Of Wonkwang University:department Of Microbiology And Immunology
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Choi Byung-min
韓国
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Choi Byung-min
Medical Resources Research Center Of Wonkwang University
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Song Yun-seon
Bioanalysis And Biotransformation Reseach Center Korea Institute Of Science And Technology
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Song Yun-seon
韓国
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Kim N‐y
College Of Pharmacy Kyung-hee University
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Kim Youn-chul
Coll. Of Pharmacy Wonkwang Univ. Kor
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Sohn D‐h
College Of Pharmacy Wonkwang University
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Kim Youn-chul
College Of Pharmacy Medicinal Resources Research Center Wonkwang University
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Kim Na-young
College Of Pharmacy Kyung-hee University
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Kim Na-young
Faculty Of Food Science Dong-a University
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