Androgen-Induced Production of Colony-Stimulating Factor (CSF) and Colony-Inhibitory Factor (CIF) in the Submandibular Gland in Female Mice
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概要
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Both testosterone (T) and 5α-dihydrotestosterone (DHT) significantly increased colony-stimulating factor (CSF) as well as colony-inhibitory factor (CIF) in the submandibular gland (SMG) in female mice. The CIF activity was completely inactivated by heating at 60℃ for 15 min, while the CSF activity was stable against the heat treatment. It was found that the CSFs obtained from the androgen-treated female mice and from normal male mice behaved identically in chromatography on hydroxylapatite and Ultro-gel AcA 34 columns. The potency of DHT to increase CSF activity was about 10 times greater than that of T.
- 公益社団法人日本薬学会の論文
著者
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Shinoda M
Department Of Biochemistry Hoshi University
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Shinoda Masato
Department Of Geography Tokyo Metropolitan University
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SATO Jun
Department of Neural Regulation, Research Institute of Environmental Medicine, Nagoya University
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Ishii Takayuki
Department Of Endoscopy The Jikei University Kashiwa Hospital
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SHIMIZU Motoyuki
Department of Molecular and Cell Genetics, School of Life Sciences, Faculty of Medicine, Tottori Uni
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Shimizu Motoyuki
Department Of Biochemistry Hoshi University
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Sato Jun
Department Of Neural Regulation Division Of Regulation Of Organ Function Research Institute Of Envir
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Ishii Takayuki
Department Of Biochemistry Hoshi University
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KANADA Tomoko
Department of Biochemistry, Hoshi University
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Shinoda Masato
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Hoshi University
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Kanada T
Department Of Biochemistry Hoshi University
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Sato Jun
Department Of Applied Physics And Chemistry The University Of Electro-communications
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Sato Jun
Department Of Biochemistry Hoshi University
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Sato Jun
Department Of Anesthesia Gunma Cancer Center
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Ishii Takayuki
Department of Applied Chemistry, Faculty of Engineering, Kanagawa University
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