STUDIES ON THE PHYSIOLOGICAL CHEMISTRY OF THE SALIVARY GLANDS XLIX. STABILITY OF PAROTIN IN AQUEOUS SOLUTION
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概要
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Both the calcium activity and the leukocyte activity of parotin in aqueous solution (pH 8.0) were relatively stable against the incubation at 37°C. The calcium activity of parotin is labile in strong acid solution (pH 1.4), but is remarkably stable in strong alkaline solution (pH 12.6). In contrast to the calcium activity, the leukocyte activity of parotin is very stable in acid solution and extremely unstable in alkaline solution. The ultraviolet absorption maximum remained at 277mμ after incubation, and the extinction coefficient at that wave length showed slight increase in both solutions of pH 1.0 and pH 11.0 after incubation. No degradation or splitting of the molecule of parotin was demonstrated by paper partition chromatography, paper electrophoresis, or ultracentrifugation.
- 社団法人 日本内分泌学会の論文
著者
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Ito Y.
Department of Physics, Yamagata University
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Shinoda Masato
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Hoshi University
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ITO YOSOJI
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, University of Tokyo
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