BIOMEDICAL APPLICATIONS OF MAGNETIC FLUIDS. I. MAGNETIC GUIDANCE OF FERRO-COLLOID-ENTRAPPED ALBUMIN MICROSPHERE FOR SITE SPECIFIC DRUG DELIVERY IN VIVO

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概要

• 論文の詳細を見る

• Magnetic guidance of magnetic albumin microsphere for site specific drug delivery was investigated in vivo. After intravenous injection in mice, magnetic microspheres localized in the site (lung) at which two permanent magnets were placed. Injection into the renal artery in rats also indicated that the microspheres were concentrated at the kidney by a magnetic field. When magnet was not applied, however, the microspheres were concentrated mainly in the liver. Such preferential localization by magnetic means suggested that magnetic albumin microspheres could become effective drug carriers with site specificity for the delivery of chemotherapeutic agents in cancer therapy.

• 公益社団法人日本薬学会の論文

著者

• Sugibayashi Kenji

  Faculty of Pharmaceutical Sciences, Josai University

• Morimoto Yasunori

  Faculty of Pharmaceutical Sciences, Josai University

• Morimoto Yasunori

  Faculty Of Pharmaceutical Sciences Josai University

• KATO YOSHIO

  Faculty of Pharmaceutical Sciences, Josai University

• OKUMURA MUTUO

  Faculty of Pharmaceutical Sciences, Josai University

• Sugibayashi Kenji

  Faculty Of Pharmaceutial Sciences Josai University

• Okumura Mutuo

  Faculty Of Pharmaceutical Sciences Josai University

• Kato Yoshio

  Faculty Of Pharmaceutical Sciences Josai University

• Kato Yoshio

  Faculty Of Engineering Shinshu University

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