A New Cytotoxic Polyhydroxysterol from Soft Coral Sarcophyton trocheliophorum
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概要
- 論文の詳細を見る
A new cytotoxic polyhydroxysterol, 23,24,-dimethylcholest-16(17)-E-en-3β, 5α, 6β, 20(S)-tetraol (2), together with nine known compounds was isolated from the soft coral Sarcophyton trocheliophorum. Their structures were determined by spectroscopic methods. Compound 2 showed potent growth inhibitory activity against human HL60 leukemia, M14 skin melanoma, and MCF7 breast carcinoma cells with EC_<50> values of 2.8,4.3,and 4.9 μg/ml, respectively, and exhibited minimal toxicity to normal human peripheral blood lymphocytes.
- 公益社団法人日本薬学会の論文
- 2000-07-01
著者
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Kini R.manjunatha
Bioscience Center Department Of Biological Science Faculty Of Science National University Of Singapo
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But P
Department Of Biology And Institute Of Chinese Medicine The Chinese University Of Hone Kong
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Sun H‐d
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Sun Han-dong
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Sun Han-dong
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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XU Hong-Xi
Chinese Medicine Laboratory, Hong Kong Jockey Club Institute of Chinese Medicine
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Chen Shao-xing
Department Of Scientific Servise Institute Of Science And Forensic Medicine
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DONG Hui
Bioscience Center, Department of Biological Science, Faculty of Science, National University of Sing
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GOU Yu-Lin
Bioscience Center, Department of Biological Science, Faculty of Science, National University of Sing
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TEO Serena
Bioscience Center, Department of Biological Science, Faculty of Science, National University of Sing
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BUT Paul
Chinese Medicinal Material Research Center, The Chinese University of Hong Kong
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But P
Institute Of Chinese Medicine The Chinese University Of Hong Kong
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Gou Yu-lin
Bioscience Center Department Of Biological Science Faculty Of Science National University Of Singapo
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Xu Hong
Chinese Medicine Laboratory Hong Kong Jockey Club Institute Of Chinese Medicine
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Xu H‐x
Chinese Medicinal Material Research Center The Chinese University Of Hong Kong
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Dong H
Chinese Univ. Hong Kong Hkg
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Teo Serena
Bioscience Center Department Of Biological Science Faculty Of Science National University Of Singapo
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Xu Hong-xi
Chinese Medicine Laboratory Hong Kong Jockey Club Institute Of Chinese Medicine
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But Paul
Chinese Medical Materials Research Centre The Chinese University
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Kini R.
Bioscience Center, Department of Biological Science, Faculty of Science, National University of Singapore
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