Three New Compounds from Kadsura longipedunculata
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概要
- 論文の詳細を見る
Two new tetrahydrofuran lignans, kadlongirins A and B (1,2), a new cadinane-type sesquiterpenoid, 2,7-di-hydroxy-11,12-dehydrocalamenene (3), together with seven known lignans, grandisin, fragransin B_1, vladirol F, kadsuralignan C, otobaphenol, isoanwulignan, and 4-[4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-2-methoxy-phenol, were isolated from the leaves and stems of Kadsura longipedunculata. The structures of these new compounds were elucidated by spectroscopic methods. Compound 2 exhibited weak anti-human immunodeficiency virus-1 activity with an EC_<50> value of 16.0μg/ml, and therapeutic index (TI) value of 6.7.
- 公益社団法人日本薬学会の論文
- 2008-08-01
著者
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Pu Jian-Xin
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Zhao Yong
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Xiao Wei-Lie
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Sun Han-Dong
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Zheng Yong-tang
中華人民共和国
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Zheng Yong-tang
Kunming Inst. Of Zoology Chinese Acad. Of Sciences
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Zheng Yong-tang
Laboratory Of Molecular Immunopharmacology Key Laboratory Of Animal Models And Human Diseases Mechan
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Yang Liu-meng
Kunming Inst. Of Zoology Chinese Acad. Of Sciences
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Sun H‐d
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Sun Han-dong
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Sun Han-dong
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Zheng Yong-tang
Laboratory Of Molecular Immunopharmacology Key Laboratory Of Animal Models And Human Disease Mechani
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Pu Jian-xin
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Xiao Wei-lie
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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GAO Xue-Mei
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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LEI Chun
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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WANG Rui-Rui
Laboratory of Molecular Immunopharmacology, Key Laboratory of Animal Models and Human Disease Mechan
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YANG Li-Bin
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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LI Li-Mei
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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HUANG Sheng-Xiong
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Xiao Wei-lie
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Gao Xue-mei
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Dong H
Chinese Univ. Hong Kong Hkg
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Li Li-mei
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Xiao Wei-lie
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Zheng Yong-tang
Laboratory Of Molecular Immunopharmacology Key Laboratory Of Animal Models And Human Disease Mechani
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Zhao Yong
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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WANG Rui-Rui
Laboratory of Molecular Immunopharmacology, Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences
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Lei Chun
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
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