Uncinoside A and B, Two New Antiviral Chromone Glycosides from Selaginella uncinata
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概要
- 論文の詳細を見る
Five compounds have been isolated from the dried whole plants of Selaginella uncinata, two of them were new chromone glycosides, 5-hydroxy-2,6,8-trimethylchromone 7-ο-β-D-glucopyranoside (uncinoside A) and 5-acetoxyl-2,6,8-trimethylchromone 7-ο-β-D-glucopyranoside (uncinoside B). Their structures were elucidated by spectroscopic methods including one- and two-dimensional NMR techniques. The other three compounds were identified as 8-methyl eugenitol, amentoflavone and hinokiflavone. Uncinoside A and B showed potent antiviral activities against respiratory syncytial virus (RSV) with IC_<50> value of 6.9 and 1.3μg/ml, moderate antiviral activities against parainfluenza type 3 virus (PIV 3) with IC_<50> value of 13.8 and 20.8 μg/ml, respectively.
- 公益社団法人日本薬学会の論文
- 2003-11-01
著者
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Ma Ling-yun
Division Of Chinese Materia Medica And Natural Products National Institute For The Control Of Pharma
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BUT Paul
Department of Biology and Institute of Chinese Medicine, The Chinese University of Hong Kong
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But P
Department Of Biology And Institute Of Chinese Medicine The Chinese University Of Hone Kong
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Wei Feng
Department Of Chinese Materia Medica And Natural Products National Institute For The Control Of Phar
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Lee S‐f
Department Of Microbiology And Immunology Dalhousie University
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Lee Song-fong
Department Of Microbiology And Immunology Dalhousie University
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Lee Spencer
Department Of Microbiology And Immunology Dalhousie University
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LEE Song
Department of Applied Oral Sciences, Faculty of Dentistry, Dalhousie University
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MA Shuang-Cheng
Department of Chinese Materia Medica and Natural Products, National Institute for the Control of Pha
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LIN Rui-Chao
Department of Chinese Materia Medica and Natural Products, National Institute for the Control of Pha
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MA Ling-Yun
Department of Chinese Materia Medica and Natural Products, National Institute for the Control of Pha
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But P
Institute Of Chinese Medicine The Chinese University Of Hong Kong
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But Paul
Department Of Biochemistry The Chinese University Of Hong Kong
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Ma Shuang-cheng
Department Of Chinese Materia Medica And Natural Products National Institute For The Control Of Phar
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Lin Rui-chao
Department Of Chinese Materia Medica And Natural Products National Institute For The Control Of Phar
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Ma Shuang-cheng
Department Of Chemistry Department Of Biology And Institute Of Chinese Medicine The Chinese Universi
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