Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XI. Reaction of 1-Methyl-2 (1H)-pyridone Derivatives with Formaldehyde and Hydrochloric Acid

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概要

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• Reaction of 1-methyl-2 (1H)-pyridone with formaldehyde and hydrochloric acid was carried out. The products proved in this reaction were 5-hydroxymethyl-1-methyl-2 (1H)-pyridone (III) in 46% yield from 1-methyl-2 (1H)-pyridone (I), 5-ethyl-3-hydroxymethyl-1-methyl-2 (1H)-pyridone (VIII) from 5-ethyl-1-methyl-2 (1H)-pyridone (VII), and 6-hydroxymethyl-1-methyl-2 (1H)-quinolone (IX) from 1-methyl-2 (1H)-quinolone (II).

• 社団法人日本薬学会の論文
• 1970-05-25

著者

• 富澤 宏

  東北薬科大学

• 本郷 弘司

  東北薬科大学

• 富澤 宏

  Tohoku College of Pharmacy

• 藤田 礼子

  Tohoku College of Pharmacy

• 本郷 弘司

  Tohoku College of Pharmacy

• 小林 裕

  Tohoku College of Pharmacy

• 小林 裕

  Central Research Laboratories Sankyo Co. Ltd.

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