Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XXV. The Diels-Alder Reaction of 1-Methyl-2 (1H)-pyridone with Fumaric Acid and Its Ester

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概要

• 論文の詳細を見る

• Studies on the Diels-Alder reaction of 1-methyl-2 (1H)-pyridone (I) with fumaric acid and its ester were carried out. Reaction of I with dimethyl fumarate in toluene gave dimethyl 2-methyl-3-oxo-2-azabicyclo [2. 2. 2] oct-7-ene-5-endo-6-exo-dicarboxylate (IV) in about 4% yield. Boiling of I and fumaric acid in water afforded 6-methyl-7-oxo-6-azabicyclo [3. 2. 1] oct-2-ene-2,8-endo-dicarboxylic acid (VII) in about 20% yield.

• 社団法人日本薬学会の論文
• 1978-08-25

著者

• 加藤 秀樹

  Tohoku College Of Pharmacy

• 本郷 弘司

  東北薬科大学

• 藤田 礼子

  Tohoku College of Pharmacy

• 本郷 弘司

  Tohoku College of Pharmacy

• 富沢 宏

  東北薬科大学

• 富沢 宏

  Tohoku College of Pharmacy

• 佐藤 昭

  Tohoku College of Pharmacy

関連論文

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• Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XIII. Syntheses of 5-endo-6-exo-Dicyano- and -Dimethoxycarbonyl-2-methyl-3-oxo-2-azabicyclo [2.2.2] oct-7-ene
• Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XII. Reaction of 2-Methyl-1 (2H)-isoquinolone with Formaldehyde and Hydrochloric Acid
• Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XI. Reaction of 1-Methyl-2 (1H)-pyridone Derivatives with Formaldehyde and Hydrochloric Acid
• Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. X. The Diels-Alder Reaction of 1-Methyl-2 (1H)-pyridone with Maleic Anhydride
• Studies on 1-Alkyl-2(1H)-pyridone Derivatives. IX. The Friedel-Crafts Reaction of 1-Methyl-2 (1H)-quinolone
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• Studies on 1-Alkyl-2(1H)-pyridone Derivatives. XXXI. : Syntheses of Isoquinoline Derivatives Using Diels-Alder Reactions of 4-Acetyl-, 4-Cyano-, and 4-Methoxycarbonyl-1-methyl-2(1H)-pyridones with 1,3-Butadiene Derivatives
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