Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XII. Reaction of 2-Methyl-1 (2H)-isoquinolone with Formaldehyde and Hydrochloric Acid

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概要

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• Reaction of 2-methyl-1 (2H)-isoquinolone (I) with formaldehyde and conc. hydrochloric acid was carried out and it was found that the product differed according to reaction conditions. The products obtained and their structure identified were 4-hydroxymethyl-2-methyl-1 (2H)-isoquinolone (II), 4,4'-methylene-bis [2-methyl-1 (2H)-isoquinolone] (III), and 4-chloromethyl-2-methyl-1 (2H)-isoquinolone (IV).

• 社団法人日本薬学会の論文
• 1970-05-25

著者

• 富澤 宏

  東北薬科大学

• 本郷 弘司

  東北薬科大学

• 富澤 宏

  Tohoku College of Pharmacy

• 藤田 礼子

  Tohoku College of Pharmacy

• 本郷 弘司

  Tohoku College of Pharmacy

• 斎藤 圀朗

  Tohoku College of Pharmacy

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