1-Alkyl-2(1H)-pyridone誘導体の研究(第21報)2-Methyl-1(2H)-thioisoquinoloneのMannich反応
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The Mannich reaction of 2-methyl-1(2H)-thioisoquino1one (II) was carried out. The products obtained were 4,4'-methylene-bis[2-methyl-1(2H)-thioisoquinolone] (III), 4-dimethylaminomethyl-2-methyl-1(2H)-thioisoquinolone (IV), 4-diethylaminomethyl-2-methyl-1(2H)-thioisoquinolone (VI), and 4-piperidinomethyl-2-methyl-1(2H)-thioisoquinolone (VII), and these structures were confirmed by nuclear magnetic resonance spectral comparison.
- 社団法人日本薬学会の論文
- 1974-01-25
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