Paxillarines A and B, New Steroidal Alkaloids from Pachysandra axillaris, and Conformation of Their Ring A Moieties
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概要
- 論文の詳細を見る
Two new steroidal alkaloids, paxillarines A (1) and B (2), were isolated from Pachysandra axillaris. Their structures were determined by means of spectrometric methods as 3α-N-methylbenzoylamino-4β-acetoxy-16β-hydroxy-20α-dimethylamino-5α-pregnane and 3α-N-methylbenzoylamino-4β-acetoxy-12β-hydroxy-20α-dimethyl-amino-5α-pregnane, respectively. Some of the expected characteristic ^1H-NMR signals were not observed due to hindered rotation when the spectra were measured on a 400 MHz spectrometer, although all of the signals appeared clearly on a 90 MHz machine. The conformation of the ring A moiety of these alkaloids is discussed.
- 社団法人日本薬学会の論文
- 1996-11-15
著者
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NAKAMURA Norio
Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University
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Nie R‐l
Laboratory Of Phytochemistry Kunming Institute Of Botany
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QUI Ming-hua
Laboratory of Phytochemistry, Kunming Institute of Botany
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NIE Rui-lin
Laboratory of Phytochemistry, Kunming Institute of Botany
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KIKUCHi Tohru
Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University
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Nie Rui-lin
Laboratory Of Phytochemistry Kunming Institute Of Botany
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Qui Ming-hua
Laboratory Of Phytochemistry Kunming Institute Of Botany
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Kikuchi Tohru
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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Nakamura Norio
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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KIKUCHI Tohru
Research Institute for Wakan-Yaku (Oriental Medicine), Toyama Medical and Pharmaceutical University
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