Synthesis of Antimicrobial Agents. VII. Synthesis and Antibacterial Activities of Furo [2,3-g] quinoline Derivatives

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概要

• 論文の詳細を見る

• As part of a series of studies on the synthesis of new antibacterial agents, tetracyclic compounds having a furo [2,3-g] quinoline moiety as a common structural unit were synthesized, and their antibacterial activities were examined. Among them, 3-methyl-7-oxo-2,3-dihydro-7H-furo [2,3-h] pyrido [1,2,3-de] [1,4] benzoxazine-6-carboxylic acid (4c) exhibited the most potent antibacterial activity against Gram-positive and-negative organisms, including Pseudomonas aeruginosa, and it showed low acute toxicity to mice.

• 社団法人日本薬学会の論文
• 1984-12-25

著者

• 田中 良明

  松島病院大腸肛門病センター

• 鈴木 和徳

  松島病院大腸肛門病センター

• 田中 良明

  松島病院外科

• 田中 良明

  Research Institute, Daiichi Seiyaku Co., Ltd.

• 鈴木 範夫

  Research Institute, Daiichi Seiyaku Co., Ltd.

• 早川 勇夫

  Research Institute, Daiichi Seiyaku Co., Ltd.

• 鈴木 和徳

  Research Institute, Daiichi Seiyaku Co., Ltd.

• 鈴木 範夫

  Exploratory Research Laboratories III, Daiichi Pharmaceutical Co., Ltd.,

• 鈴木 範夫

  Exploratory Research Laboratories Iii Daiichi Pharmaceutical Co. Ltd.

• 田中 良明

  Research Institute Daiichi Seiyaku Co. Ltd.

• 鈴木 範夫

  Research Institute Daiichi Seiyaku Co. Ltd.

• 早川 勇夫

  第一製薬

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