Synthetic Chemotherapeutic Agents. I. Synthesis of 2-Substituted Thiazolo [5,4-f] quinoline Derivatives. (1)
スポンサーリンク
概要
- 論文の詳細を見る
By using 6-aminobenzothiazoles as starting meterial, a series of 2-substituted 6-ethyl-6,9-dihydro-9-oxothiazolo [5,4-f] quinoline-8-carboxylic acids has been prepared through successive steps of, e.g. condensation with diethyl ethoxymethylenemalonate, Gould-Jacobs reaction, N-alkylation and hydrolysis. These compounds were evaluated for antibacterial activities in vitro. The 2-chloro derivative (10d) showed nearly the same activity with nalidixic acid.
- 公益社団法人日本薬学会の論文
- 1976-01-25
著者
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鈴木 範夫
Research Institute, Daiichi Seiyaku Co., Ltd.
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鈴木 範夫
Research Institute Daiichi Seiyaku Co. Ltd.
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門矢 静夫
Research Institute Daiichi Seiyaku Co. Ltd.
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堂森 廉三
Research Institute Daiichi Seiyaku Co. Ltd.
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高村 功
Research Institute, Daiichi Seiyaku Co., Ltd.
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高村 功
Research Institute Daiichi Seiyaku Co. Ltd.
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