スルフォンアミド誘導体の転位反応(第4報)ピリジン及びキノリン1-オキシドのスルフォンアミド誘導体の転位反応
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概要
- 論文の詳細を見る
Heating of 1-oxides of 2-(N-acetoacetyl) pyridinesulfonamide, 4-methyl-2-(N-acetoacetyl) pyridinesulfonamide, 4-(N-acetoacetyl) pyridinesulfonamide, and 4-(N-acetoacetyl)-quinolinesulfonamide each in 10% sodium hydroxide at 90〜95°causes rearrangement reaction with liberation of sulfur dioxide to form respectively, 2-pyridineacetic acid, 1-oxides of 4-methyl-2-pyridineacetic acid, 4-pyridineacetic acid, and 4-quiolineacetic acid. These substances were confirmed by their respective decarboxylation and derivation to 2-picoline 1-oxide, 2,4-lutidine 1-oxide, 4-picoline 1-oxide, and lepidine 1-oxide.
- 公益社団法人日本薬学会の論文
- 1955-02-20
著者
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堂森 廉三
Research Institute Daiichi Seiyaku Co. Ltd.
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内藤 武男
Yanagishima Research Laboratory, Daiichi Seiyaku Co., Ltd.
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堂森 廉三
Yanagishima Research Laboratory, Daiichi Seiyaku Co., Ltd.
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- スルフォンアミド誘導体の転位反応(第4報)ピリジン及びキノリン1-オキシドのスルフォンアミド誘導体の転位反応
- スルフォンアミド誘導体の転位反応(第3報)反応機構に就いての考察