スルフォンアミド誘導体の転位反応(第3報)反応機構に就いての考察
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概要
- 論文の詳細を見る
Considerations were made on the reaction mechanism of a rearrangement reaction whereby compounds of p- or o-NO_2-C_6H_4-SO_2NH-COCH_2R type (where R is -COCH_3,-CN, -COOR, or -C_6H_5 group) easily undergo decomposition in the presence of alkali, with liberation of sulfur dioxide to form p- or o-nitrophenylacetamide or its derivatives. It was shown that this reaction is an intramolecular rearrangement and that the me methylene group present must be active in order that this rearrangement reaction proceeds, which was explained by the fact that N-(o-nitrophenylacetyl)-o-nitrobenzenesulfonamide is more reactive than N-phenylacetyl-o-nitrobenzenesulfonamide.
- 公益社団法人日本薬学会の論文
- 1955-02-20
著者
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堂森 廉三
Research Institute Daiichi Seiyaku Co. Ltd.
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内藤 武男
Yanagishima Research Laboratory, Daiichi Seiyaku Co., Ltd.
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堂森 廉三
Yanagishima Research Laboratory, Daiichi Seiyaku Co., Ltd.
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下田 六夫
Yanagishima Research Laboratory, Daiichi Seiyaku Co., Ltd.
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下田 六夫
Yanagishima Research Laboratory Daiichi Seiyaku Co. Ltd.
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- スルフォンアミド誘導体の転位反応(第4報)ピリジン及びキノリン1-オキシドのスルフォンアミド誘導体の転位反応
- スルフォンアミド誘導体の転位反応(第3報)反応機構に就いての考察