Evaluation of epidural buprenorphine and droperidol for postoperative analgesia in anal surgery.

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The analgesic effect of epidural buprenorphine and droperidol was studied on 350 postoperative patients following anal surgery (hemorrhoid, fistula, fissure). 350 cases were divided into 3 groups. Group 1 (150 cases); Only intraoperative spinal anesthesia using Neopercamin S®. Group 2a (100 cases); Intraoperative spinal anesthesia using NPS® and postoperative injection of buprenophine 0.10-0.15mg through epidural catheter, five times (every 12 hours). Group 2b (100 cases); Same as group 2a, but added droperidol 2.5mg through epidural catheter first two times. <BR>The results suggested that the epidural administration of Buprenorphine was effective means for postoperative analgesia, but slight urinary disturbance, transient fever and nausea were occured.The epidural administration of droperidol in combination with buprenorphine was useful to prevent nausea and vomiting and also to reinforce and to prolong the analgesic effect of buprenorphine.
日本大腸肛門病学会の論文