Effect of Repeated Intake of Disaccharides on Glucose Metabolism and Insulin Secretion in Healthy Adults - Comparison between Sucrose and Maltose
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概要
- 論文の詳細を見る
We observed glucose metabolism and insulin secretion in healthy young men after intake of large amounts of sugar. Ten subjects, with the randomized cross-over design, ingested sucrose or maltose solution hourly from 10:00 to 13:00 (75 g in 225 ml water per time). Plasma concentrations of glucose, insulin and c-peptide were measured in fasting, at 30 min after each intake and at 2 hr after last intake. Plasma glucose concentration increased after the first intake and decreased to the fasting level from the second intake. Plasma insulin and c-peptide concentrations increased from the first intake and retained throughout following intakes. Plasma concentrations of glucose, insulin and c-peptide were higher in maltose group than in sucrose group and the significant differences were observed after the last intake. In the present study, glucose concentration maintained in the normal range after intake of large amounts of disaccharide and insulin secretion responded well to this repeated intake of disaccharide, however, maltose tended to induce insulin resistance compared with sucrose.
- 社団法人日本薬学会の論文
- 2003-06-01
著者
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Wang Pei-yu
Department Of Social Medicine And Health Education School Of Public Health Peking University
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Wang Yuan
Internal Medicine Fourth Affiliated Hospital Hebei Medical University
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QIN LI-QIANG
Department of Nutrition and Food Hygiene, School of Radiation Medicine and Public Health, Soochow Un
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KANEKO TAKASHI
Department of Environmental Health, School of Medicine, Yamanashi University
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SATO AKIO
Department of Environmental Health, School of Medicine, Yamanashi University
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Li Jue
Department of Environmental Health, School of Medicine, University of Yamanashi
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Wang Yuan
Department of Environmental Health, School of Medicine, University of Yamanashi
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Li Jue
Department Of Cardiology Tongji Hospital Of Tongji University
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Li Jue
Department Of Environmental Health School Of Medicine University Of Yamanashi:heart Lung And Blood V
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Qin Li-qiang
Jiangsu Provincial Key Lab. Of Radiation Medicine And Protection
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Kaneko Takashi
Department Of Environmental Health School Of Medicine Yamanashi University
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Sato Akio
Department Of Environmental Health School Of Medicine Yamanashi University
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Wang P‐y
Department Of Social Medicine And Health Education School Of Public Health Peking University
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Wang Pei-yu
中華人民共和国
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Wang Pei-yu
Department Of Preventive Medicine And Health Education School Of Public Health Beijing University
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Qin Li-qiang
Department Of Nutrition And Food Hygiene School Of Radiation Medicine & Public Health Soochow Un
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Wang Yuan
Department Of Animal Resource & Science Dankook University
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Kaneko Takashi
Department Of Chemistry And Chemical Engineering Faculty Of Engineering Niigata University
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Sato Akio
Department Of Agricultural Chemistry Faculty Of Agriculture Tohoku University
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Kaneko Takashi
Department Of Applied Biological Science Science University Of Tokyo
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SATO Akio
Department of Environmental Health, Yamanashi Medical University
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KANEKO Takashi
Department of Environmental Health, Yamanashi Medical University
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WANG Pei-Yu
Department of Environmental Health, Yamanashi Medical University
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