高3倍性弘前肉腫細胞の染色体調査

概要

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According to Usubuchi and Abe ('60) a tetraploid subline of the Hirosaki sarcoma established by them was characterized by the modal numbers of chromosomes ranging from 70 to 72. A reexamination was made of the chromosomes by authors in 68 tumor cells of the subline, and found that the number of chromosomes varied from 54 to 109 with a mode at 67 (29.4%) as shown in Table 1. The rod-, V- and J-shaped elements were variable in number, the mean frequency of their occurrence being 25.66±1.05, 18.44±0.92 and 23.04±0.94, respectively (Table 2). The large V-elements showed a numerical variation from 2 to 6, with a mode at 4. There was no correlation between the total chromosome-number and the number of V-shaped elements. On the basis of the above findings, the following assumption is possible: the stem-cells of this subline may be in process (or on way) of alteration, and as a result the chromosomes manifest a remarkable fluctuation in both number and morphology.
社団法人日本動物学会の論文
1961-05-15