EFFECTS OF ANDROGEN ON DNA SYNTHESIS IN IMMATURE RAT UTERI

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概要

• 論文の詳細を見る

• The effects of testosterone and 17β-estradiol on uterine thymidine kinase (TK) activity in immature rats were investigated. Injection of either compound alone resulted in a more than 30-fold increase in TK activity 30 hr later. Injection of the two compounds together resulted in an even greater increase in TK activity and in the activities of its isozymes separated by DEAE cellulose column chromatography. Autoradiographic examination showed that testosterone alone induced marked DNA synthesis in the endometrial stroma and myometrium, but not in the endometrial epithelium, and that its effect on DNA synthesis in all these tissues was enhanced by the additional injection of 17β-estradiol.

• 日本組織細胞化学会の論文

著者

• Mizuhira Vinci

  Department Of Anatomy And Cell Biology Medical Research Institute Tokyo Medical And Dental Universit

• Mizuhira Vinci

  Departments Of Cell Biology Medical Research Institute Tokyo Medical And Dental University

• Sakamoto Shinobu

  Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University

• Kumai Akihiko

  Departments Of Endocrinology Medical Research Institute Tokyo Medical And Dental University

• Sugiura Y

  Department Of Endocrinology Medical Research Institute Tokyo Medical And Dental Universify

• Sugiura Yoshie

  Department Of Cell Biology Medical Research Institute Tokyo Medical And Dental University

• OKAMOTO RYOHEI

  Department of Endocrinology, Medical Research Institute, Tokyo Medical and Dental Universify

• KAWASAKI TOHRUI

  Departments of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University

• SASSA SHUJI

  Departments of Endocrinology, Medical Research Institute, Tokyo Medical and Dental University

• Sakamoto Shinobu

  Department Of Endocrinology Medical Research Institute Tokyo Medical And Dental University

• Sassa Shuji

  Departments Of Endocrinology Medical Research Institute Tokyo Medical And Dental University

• Kawasaki Tohru

  Nihon Tokushu Noyaku Seizo Co. Ltd.

• Mizuhira Vinci

  Department Of Anatomy & Cell Biology Tokyo Medical & Dental University

• Okamoto R

  Department Of Endocrinology Medical Research Institute Tokyo Medical And Dental Universify

• Okamoto Ryohei

  Department Of Endocrinology Medical Research Institute Tokyo Medical And Dental University

• KUMAI AKIHIKO

  Department of Chemistry, Research Laboratories, Teikoku Hormone Mfg. Co., Ltd.

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