IMMUNOCYTOCHEMICAL LOCALIZATION OF AROMATASE IN OVARIES OF SOME RODENTS, COW AND HUMAN
スポンサーリンク
概要
- 論文の詳細を見る
In order to clarify the in vivo localization of aromatase in the ovarian tissues of rat, mouse, guinea pig, golden hamster, cow and human, immunocytochemical investigations using the anti-human placental aromatase II cytochrome P-450 antibody were carried out by the PAP or indirect fluorescent antibody method. Immunoreactive aromatase was detected on the theca interna, as well as the interstitial gland cells of both immature and mature rodent ovaries and the corpus luteum cell of mature rodent ovaries. The immunoreactivity was also demonstrated on the theca interna cell and corpus luteum cell of cow and human ovaries. Only in large preovulatory follicles of the mature rodent ovary did the granulosa cell react with the antibody of this enzyme, while granulosa cells in all the other follicles were consistently negative in this immunoreaction. These results might imply that the theca interna cell and interstitial gland cell presumably have a fundamental ability of the aromatization from androgens to estrogens in the mature and immature ovaries.
- 日本組織細胞化学会の論文
著者
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Matsuda Hiroshi
Department of Nuclear Medicine, Saitama International Medical Center
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Ishimura Kazunori
Department of Anatomy and Cell Biology, Institute of Health Biosciences, The University of Tokushima
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Matsuda Hiroshi
Department Of Cardiovascular Surgery Hyogo Medical College
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Fujita Hisao
Department Of Anatomy Osaka University Medical School
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Fujita Hisao
Department Of Anatomy Hiroshima University School Of Medicine
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Ishimura K
Department Of Anatomy And Cell Biology Institute Of Health Biosciences The University Of Tokushima G
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Ishimura Kazunori
Department Of Anatomy And Cell Biology Institute Of Health Biosciences The University Of Tokushima G
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Ishimura Kazunori
Department Of Anatomy And Cell Biology School Of Medicine Tokushima University
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OSAWA YOSHIO
Medical Foundation of Buffalo, Inc.
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Osawa Yoshio
Hauptman-woodward Medical Research Institute Inc.
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Fujita H
Osaka Univ. Medical School Osaka
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Ishimura Kazunori
Department Of Anatomy And Cell Biology Institute Of Health Biosciences The University Of Tokushima G
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Matsuda Hiroshi
Department Of Anatomy Osaka University Medical School
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