IMMUNOCYTOCHEMICAL STUDY ON THE LOCALIZATION OF AROMATASE IN THE OVARY OF GOLDEN HAMSTER, GUINEA PIG AND COW
スポンサーリンク
概要
- 論文の詳細を見る
The precise localization of aromatase, the estrogen synthesizing enzyme, in the ovary of golden hamster, guinea pig and cow were immunocytochemically studied using anti-human placental aromatase cytochrome P-450 antisera. The positive reaction for aromatase was detected mainly in the granulosa cells of large preovulatory follicles of all species studied. In addition, some cells of corpora lutea showed weak positive reaction. The granulosa cells of smaller follicles, theca interna cells, oocytes and peritoneal epithelial cells were entirely negative to the immunostaining. The intensity of the immunoreaction to the anti-aromatase antibody was stronger in the hamster ovary than in the ovaries of the guinea pig and cow. Electron microscopic examination revealed that the positively stained granulosa cells of hamster had well developed smooth endoplasmic reticulum. The present results and our previous data obtained in rats and mice ovaries suggest that the appearance of aromatase in the granulosa cell of the preovulatory follicle is a general phenomenon in many species of mammals.
- 日本組織細胞化学会の論文
著者
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Ishimura Kazunori
Department of Anatomy and Cell Biology, Institute of Health Biosciences, The University of Tokushima
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Fujita Hisao
Department Of Anatomy Osaka University Medical School
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Fujita Hisao
Department Of Anatomy Hiroshima University School Of Medicine
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Ishimura K
Department Of Anatomy And Cell Biology Institute Of Health Biosciences The University Of Tokushima G
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Ishimura Kazunori
Department Of Anatomy And Cell Biology Institute Of Health Biosciences The University Of Tokushima G
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Ishimura Kazunori
Department Of Anatomy And Cell Biology School Of Medicine Tokushima University
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ZHONG CISHENG
Faculty of Basic Medical Sciences, Shanghai Medical University
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YOSHINAGA-HIRABAYASHI TOMOKO
Department of Anatomy, Osaka University Medical School
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KITAWAKI JO
Endocrine Biochemistry Department, Medical Foundation of Buffalo
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OSAWA YOSHIO
Endocrine Biochemistry Department, Medical Foundation of Buffalo
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Kitawaki J
Kyoto Prefectural Univ.
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Osawa Yoshio
Hauptman-woodward Medical Research Institute Inc.
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Zhong Cisheng
Faculty Of Basic Medical Sciences Shanghai Medical University
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Yoshinaga-hirabayashi Tomoko
Department Of Anatomy Osaka University Medical School
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Fujita H
Osaka Univ. Medical School Osaka
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Ishimura Kazunori
Department Of Anatomy And Cell Biology Institute Of Health Biosciences The University Of Tokushima G
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OSAWA Yoshio
Endocrine Biochemistry Department Medical Foundation of Buffalo, Buffalo,N. Y., U.S.A.
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